The association between aortic valve stenosis and gastrointestinal bleeding, 
traditionally known as Heyde's syndrome, is the result of a quantitative loss of 
the highest molecular weight von Willebrand multimers (type 2A von Willebrand 
syndrome). This results in bleeding from areas of high shear stress such as 
gastrointestinal angiodysplasias. Correction of this bleeding diathesis after 
surgical aortic valve replacement has been well described. The effect of 
transcutaneous aortic valve implantation on Heyde's syndrome has yet to be 
studied. Herein, we report a patient with severe aortic stenosis, type 2A von 
Willebrand syndrome, and hemorrhagic shock from gastrointestinal bleeding who 
underwent successful transcutaneous aortic valve implantation.