The GeneWeaver data and analytics website (www.geneweaver.org) is a publically 
available resource for storing, curating and analyzing sets of genes from 
heterogeneous data sources. The system enables discovery of relationships among 
genes, variants, traits, drugs, environments, anatomical structures and diseases 
implicitly found through gene set intersections. Since the previous review in 
the 2012 Nucleic Acids Research Database issue, GeneWeaver's underlying 
analytics platform has been enhanced, its number and variety of publically 
available gene set data sources has been increased, and its advanced search 
mechanisms have been expanded. In addition, its interface has been redesigned to 
take advantage of flexible web services, programmatic data access, and a refined 
data model for handling gene network data in addition to its original emphasis 
on gene set data. By enumerating the common and distinct biological molecules 
associated with all subsets of curated or user submitted groups of gene sets and 
gene networks, GeneWeaver empowers users with the ability to construct data 
driven descriptions of shared and unique biological processes, diseases and 
traits within and across species.