Among the amiodarone-induced thyroid dysfunctions, thyrotoxicosis is the most 
troublesome and with the highest rate of morbidity and mortality. Treatment 
consists in the use of a high dose of anti-thyroid drugs and steroids in an 
isolated form or in combination. Association of several other drugs have been 
proposed for the treatment of refractory cases. In this study we report the case 
of a 40 y.o. patient, with a history of idiopatic dilated miocardiopathy, who 
developed severe amioradone-induced thyrotoxicosis after heart transplantation. 
Since the patient did not respond to an initial treatment consisting of a high 
dose of anti-thyroid drugs combined with steroids, a low dose of lithium 
carbonate was added for a short period of time, which resulted in normalization 
of the thyroid function. In this case, the addition of lithium carbonate to the 
two other drugs resulted in a successful and safety therapy in controlling 
amiodarone-induced thyrotoxicosis.