Growth retardation is a consistent finding in Williams-Beuren syndrome. The 
cause of short stature in this syndrome is unknown. Endocrine studies have 
failed to reveal abnormalities in the growth hormone-insulin-like growth factor 
I axis. We report a boy with confirmed Williams-Beuren syndrome, who was found 
to have classical growth hormone deficiency and responded well to growth hormone 
therapy.
CONCLUSION: Although growth hormone deficiency is not likely to be a common 
cause of short stature in Williams-Beuren syndrome, we nevertheless recommend 
evaluation of the growth hormone-insulin-like growth factor I axis in all cases.