The authors present a case of an arteriovenous malformation of the central 
sulcus treated with Gamma Knife surgery. The patient developed perilesional 
edema 9 months after treatment and experienced severe headache and hemiparesis. 
Her symptoms were refractory to corticosteroid therapy and pain management. She 
was subsequently treated with bevacizumab with striking improvement in her 
symptoms and results of neuroimaging studies. This is the first time that 
bevacizumab has been used to control severe refractory perilesional edema 
related to an intracranial arteriovenous malformation.