Adeno-associated viral vectors can be used as a platform for delivering 
biological countermeasures against pandemic and biological threats. We show that 
vector delivery of two antibody components of the ZMapp product is effective in 
mice against systemic and airway challenge with a mouse-adapted strain of Ebola 
virus. This platform provides a generic manufacturing solution and overcomes 
some of the delivery challenges associated with repeated administration of the 
protective protein.