A suckling baby with microcephaly, craniostenosis, downward slanting palpebral 
fissues, malformed ears, cerebral, cardiac and intestinal malformation, and 
partial 6q25 leads to 6qter trisomy is presented. The baby is the second child 
of a mother with balanced translocation : 46,XX,t(2;6)(q37,q25). The first child 
with a similar phenotype and cardiac malformation did not undergo cytogenetic 
investigation and died at 4 months.