Molluscum contagiosum is a viral infection of the skin and mucous membranes that 
is caused by infection with the molluscum contagiosum virus. Molluscum 
contagiosum can be acquired from skin to skin contact which may be during play, 
in a swimming pool, or through sexual contact. Sexually acquired molluscum is 
rare in younger children, but becomes quite common during adolescence and young 
adulthood, after the sexual debut. It has been long known that the human 
papillomavirus, which causes genital warts, i.e., condyloma accuminatum, can be 
vertically transmitted through an infected genital tract. Children may not 
manifest condyloma lesions for a few years. The entity of congenital molluscum 
has been debated in the literature and only three cases of suspected congenital 
molluscum have been reported. We report on four more infants with congenital 
molluscum, two children with congenital lesions, and two children with onset of 
lesions at 6 weeks of age. Two children had single cutaneous lesions on the 
extremities and two had lesions of the scalp consistent with the site of 
cervical pressure. Congenital molluscum appears to be a more common entity than 
previously reported. Vertical transmission of molluscum should be considered for 
all infantile cases of molluscum.