BACKGROUND: Currarino syndrome is a rare condition characterized by presacral 
mass, anorectal malformation and sacral dysgenesis.
CASE PRESENTATION: We report the case of a child that presented chronic 
constipation, encopresis and mycrocephaly. The characteristics were initially 
compatible with a case of functional constipation and a therapy with 
polyethylene glycol was prescribed. After a year, because of poor response, a 
plain abdominal X-ray was performed, detecting sacrum abnormalities. Finally, a 
CGH-array analysis was performed and a form of Currarino Syndrome caused by a 
rare 7q36 microdeletion, was diagnosed.
CONCLUSION: Occult spinal dysraphism should be suspected in case of poor 
polyethylene glycol responder constipation, even when evident sacral 
abnormalities on the physical examination are not detected.