The amniotic band syndrome is a collection of fetal malformations associated 
with fibrous bands that appear to entangle or entrap various fetal parts in 
utero, leading to deformation, malformation, or disruption. This syndrome is 
given many names yet follows a clearly defined clinical pattern. Misdiagnosis 
and inappropriate family counseling are chronic features. This article reviews 
the clinical features of the amniotic band syndrome, its epidemiology, and the 
status of prenatal and neonatal diagnosis. The spectrum of malformations 
associated with amniotic bands is summarized and illustrated. Major etiologic 
theories are examined. It is recommended that the clinician involved in the 
delivery of any infant manifesting elements of this unusual combination of 
defects seek specialized consultation in the pursuit of an accurate and precise 
diagnosis and appropriate genetic counseling.