We report the anaesthetic management of a 48-year-old male patient with 
Deafness, Onycho-Osteodystrophy and mental Retardation syndrome, epilepsy and 
cerebral palsy who had two dental procedures under anaesthetic care. For the 
first short examination sedoanalgesia was employed and the second, longer, 
procedure was performed under general anaesthesia. His airway management was 
moderately difficult and the postoperative period was complicated by partial 
seizures involving the upper extremity and a short period of decreased oxygen 
saturation. The potential anaesthetic implications of Deafness, 
Onycho-Osteodystrophy and mental Retardation syndrome are highlighted.