We report two observations of antenatal diagnosis of Apert syndrome. This 
uncommon genetic disorder suggest an autosomal dominant inheritance, but almost 
all cases described are sporadic; the responsible gene is yet not located. 
Ultrasonographic detection is difficult, based on the following signs: 
brachycephalic skull (unusually detected), flat facial profile with a nasal 
bridge depression, tall appearance of the forehead (inconstant), total bilateral 
and symmetrical syndactylies of the hands and feet. At last we present our 
arguments for medical abortion, when this disorder is detected.