Lemierre's syndrome is a rare but life-threatening condition characterized by an 
oropharyngeal infection typically secondary to Fusobacterium necrophorum 
resulting in septic thrombophlebitis of the internal jugular vein. Streptococcus 
intermedius is a particularly rare cause of Lemierre's syndrome with only a few 
cases reported in the literature. Here we describe a rare case of Lemierre's 
syndrome, caused by Streptococcus intermedius, likely secondary to an 
odontogenic infection, found to have a cervical epidural abscess with 
concomitant large retropharyngeal and prevertebral abscesses on presentation, in 
whom the clinical course was further complicated by an extensive cerebral venous 
sinus thrombosis. However, despite grave complications, early diagnosis and 
appropriate emergency management including intravenous antibiotics and surgical 
intervention led to a successful recovery, thus demonstrating that aggressive 
measures can potentially lead to a favorable outcome.