This paper presents an overview of the studies directed at helping post-coma 
persons with minimally conscious state improve their adaptive behavior. 
Twenty-one studies were identified for the 2000-2010 period (i.e., a period in 
which an intense debate has occurred about diagnostic, rehabilitative, 
prognostic, and ethical issues concerning people with severe acquired brain 
injury). Three of the 21 studies involved transcortical magnetic or deep brain 
stimulation. Six studies focused on the provision of multisensory stimulation or 
music therapy. The remaining 12 studies involved the use of response-related 
(contingent) stimulation and assistive technology. The outcomes of the studies, 
which were generally reported as positive, were discussed in terms of (a) the 
size (quantitative relevance) of the changes obtained, (b) the 
credibility/reliability of the changes, in light of the methodological 
conditions of the studies, and (c) the level of engagement and interaction 
involvement of the participants. Relevant issues for future research were also 
examined.