Author information:
(1)1] Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain 
Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario M5G 
1L7, Canada [2] Laboratory Medicine and Pathobiology, University of Toronto, 
Toronto, Ontario M5S 1A8, Canada [3] Division of Neurosurgery, University of 
Toronto, Toronto, Ontario M5S 1A8, Canada [4].
(2)1] Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 
69120 Heidelberg, Germany [2] Department of Pediatric Oncology, Hematology and 
Immunology, University of Heidelberg, Heidelberg 69120, Germany [3] German 
Cancer Consortium (DKTK), Heidelberg 69120, Germany [4].
(3)1] German Cancer Consortium (DKTK), Heidelberg 69120, Germany [2] Division of 
Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg 69120, 
Germany.
(4)1] German Cancer Consortium (DKTK), Heidelberg 69120, Germany [2] Division of 
Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg 
69120, Germany.
(5)Department of Molecular Genetics, Banting and Best Department of Medical 
Research, The Donnelly Centre, University of Toronto, Toronto, Ontario M4N 1X8, 
Canada.
(6)1] German Cancer Consortium (DKTK), Heidelberg 69120, Germany [2] Genome 
Biology, European Molecular Biology, Laboratory Meyerhofstr. 1, Heidelberg 
69117, Germany.
(7)1] Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain 
Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario M5G 
1L7, Canada [2] Laboratory Medicine and Pathobiology, University of Toronto, 
Toronto, Ontario M5S 1A8, Canada.
(8)Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain 
Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario M5G 
1L7, Canada.
(9)Department of Genetics, Norris Cotton Cancer Center, Dartmouth Medical 
School, Lebanon, New Hampshire 03756, USA.
(10)1] Division of Pediatric Neurooncology, German Cancer Research Center 
(DKFZ), 69120 Heidelberg, Germany [2] German Cancer Consortium (DKTK), 
Heidelberg 69120, Germany.
(11)1] German Cancer Consortium (DKTK), Heidelberg 69120, Germany [2] Division 
of Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg 69120, 
Germany.
(12)Department of Neurology, Harvard Medical School, Children's Hospital Boston, 
MIT, Boston, Massachusetts 02115, USA.
(13)Department of Pathology, The University of Texas MD Anderson Cancer Center, 
Houston, Texas 77030, USA.
(14)1] Ontario Cancer Institute, Princess Margaret Cancer Centre-University 
Health Network, Toronto, Ontario M5G 1L7, Canada [2] Ontario Institute for 
Cancer Research, Toronto, Ontario M5G 1L7, Canada.
(15)Cancer Epigenetics Discovery Performance Unit, GlaxoSmithKline 
Pharmaceuticals, Collegeville, Pennsylvania 19426, USA.
(16)Department of Oncogenomics, Academic Medical Center, Amsterdam 1105, The 
Netherlands.
(17)1] Department of Pediatric Oncology, Hematology and Immunology, University 
of Heidelberg, Heidelberg 69120, Germany [2] German Cancer Consortium (DKTK), 
Heidelberg 69120, Germany [3] CCU Pediatric Oncology, German Cancer Research 
Center (DKFZ), Heidelberg 69120, Germany.
(18)1] Centre for High-Throughput Biology, Department of Microbiology & 
Immunology, University of British Columbia, Vancouver, V6T 1Z4 British Columbia, 
Canada [2] Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, 
Vancouver, British Columbia V5Z 1L3, Canada.
(19)1] Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, 
Vancouver, British Columbia V5Z 1L3, Canada [2] Department of Medical Genetics, 
University of British Columbia, Vancouver, British Columbia V6H 3N1, Canada.
(20)Department of Pediatrics and National Capital Consortium, Uniformed Services 
University, Bethesda, Maryland 20814, USA.
(21)Department of Neurosurgery, University of Utah School of Medicine, Salt Lake 
City, Utah 84132, USA.
(22)Pediatric Neurosurgery, Catholic University Medical School, Gemelli 
Hospital, Rome 00168, Italy.
(23)Department of Neurology and Neurological Sciences, Stanford University 
School of Medicine, Stanford, California 94305, USA.
(24)Department of Pediatrics, Virginia Commonwealth, Richmond, Virginia 
23298-0646, USA.
(25)Department of Pathology, University of Warsaw, Children's Memorial Health 
Institute University of Warsaw, Warsaw 04-730, Poland.
(26)Division of Anatomical Pathology, Department of Pathology and Molecular 
Medicine, McMaster University, Hamilton General Hospital, Hamilton, Ontario L8S 
4K1, Canada.
(27)1] Department of Pediatric Oncology, Hematology and Immunology, University 
of Heidelberg, Heidelberg 69120, Germany [2] German Cancer Consortium (DKTK), 
Heidelberg 69120, Germany.
(28)1] German Cancer Consortium (DKTK), Heidelberg 69120, Germany [2] Department 
of Neuropathology Ruprecht-Karls-University Heidelberg, Institute of Pathology, 
Heidelberg 69120, Germany.
(29)1] University of Michigan Cell and Developmental Biology, Ann Arbor, 
Michigan 48109-2200, USA [2] Department of Neurosurgery, University of Michigan 
Medical School, Ann Arbor, Michigan 48109, USA.
(30)Department of Neurosurgery, University of Michigan Medical School, Ann 
Arbor, Michigan 48109, USA.
(31)Department of Neurosurgery, University of California San Francisco, San 
Francisco, California 94143-0112, USA.
(32)Departments of Neurology, Pediatrics, and Neurosurgery, University of 
California, San Francisco, The Helen Diller Family Cancer Research Building, San 
Francisco, California 94158, USA.
(33)1] Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain 
Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario M5G 
1L7, Canada [2] Department of Neuro-oncology, The Hospital for Sick Children, 
Toronto, Ontario M5G 1X8, Canada.
(34)Department of Haematology and Oncology, The Hospital for Sick Children, 
Toronto, Ontario M5G 1X8, Canada.
(35)1] Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain 
Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario M5G 
1L7, Canada [2] Laboratory Medicine and Pathobiology, University of Toronto, 
Toronto, Ontario M5S 1A8, Canada [3] Division of Neurosurgery, University of 
Toronto, Toronto, Ontario M5S 1A8, Canada.
(36)Departments of Pediatrics and Human Genetics, McGill University and the 
McGill University Health Center Research Institute, Montreal, Quebec H3Z 2Z3, 
Canada.
(37)Department of Neuro-oncology, The Hospital for Sick Children, Toronto, 
Ontario M5G 1X8, Canada.
(38)Genome Biology, European Molecular Biology, Laboratory Meyerhofstr. 1, 
Heidelberg 69117, Germany.
(39)1] Ontario Cancer Institute, Princess Margaret Cancer Centre-University 
Health Network, Toronto, Ontario M5G 1L7, Canada [2] Ontario Institute for 
Cancer Research, Toronto, Ontario M5G 1L7, Canada [3] Department of Medical 
Biophysics, University of Toronto, Toronto, Ontario M5G 1X8, Canada.
(40)1] Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain 
Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario M5G 
1L7, Canada [2] Laboratory Medicine and Pathobiology, University of Toronto, 
Toronto, Ontario M5S 1A8, Canada [3] Division of Neurosurgery, University of 
Toronto, Toronto, Ontario M5S 1A8, Canada [4] Department of Molecular Genetics, 
University of Toronto, Toronto, Ontario M5S 1A8, Canada.
(41)1] Division of Pediatric Neurooncology, German Cancer Research Center 
(DKFZ), 69120 Heidelberg, Germany [2] Department of Pediatric Oncology, 
Hematology and Immunology, University of Heidelberg, Heidelberg 69120, Germany 
[3] German Cancer Consortium (DKTK), Heidelberg 69120, Germany.
(42)1] German Cancer Consortium (DKTK), Heidelberg 69120, Germany [2] University 
of Michigan Cell and Developmental Biology, Ann Arbor, Michigan 48109-2200, USA 
[3] CCU Neuropathology, German Cancer Research Center (DKFZ), Heidelberg 69120, 
Germany.