BACKGROUND/OBJECTIVE: The identification of the different subtypes of 
amiodarone-induced thyrotoxicosis (AIT) may provide a rational basis for the 
choice of the appropriate medical treatment. The aim of this study was to 
evaluate differential diagnosis and treatment regimens of AIT in children and 
adolescent.
PATIENTS: We reported 3 patients: A 6.7 years old boy with type I AIT; a 17.9 
years old girl with type II AIT and a 14.6 years old girl with mixed type AIT.
CONCLUSIONS: AIT is not an uncommon complication in countries with low iodine 
intake. AIT can be asymptomatic and can occur at any time in patients receiving 
amiodarone therapy. It is also very important to distinguish the type of AIT 
when planning therapy. Steroid therapy should be started when findings indicate 
type II or mixed-type AIT. Beta blockers may prevent heart thyrotoxicosis and 
recurrence of primary arrhythmia if amiodarone is discontinued.