Werner's syndrome (adult progeria) is a rare autosomal recessive condition 
characterized mainly by a characteristic habitus (short stature, light body 
weight) scleroderma like changes of the limbs and premature aging. Chronic leg 
ulcers appears in about fifty per cent of the patients. These ulcers can be 
related to the combination of mechanical factors on atrophic subcutaneous tissue 
and skin of the feet and leg associated with early arteriosclerosis (20%) and 
diabetes mellitus (60%).