Franco, CMC, Carneiro, MAS, de Sousa, JFR, Gomes, GK, and Orsatti, FL. Influence 
of high- and low-frequency resistance training on lean body mass and muscle 
strength gains in untrained men. J Strength Cond Res 35(8): 2089-2094, 2021-The 
aim of this study was to investigate whether high-frequency resistance training 
(HFRT) performs better in lean body mass (LBM) and muscle strength gains when 
compared with low-frequency resistance training (LFRT). Eighteen untrained males 
(height: 1.76 ± 0.05 m, body mass: 78.3 ± 13.5 kg, and age: 22.1 ± 2.2 years) 
were randomly allocated into HFRT (n = 9) and LFRT (n = 9). Muscle strength {1 
repetition maximum (RM) (bench press [BP] and unilateral leg extension [LE])} 
and LBM (DXA) were assessed at before and after 8 weeks of training. Both groups 
performed 7 whole-body resistance exercises, standardized to 10 sets per week, 
8-12 maximal repetitions, and 90-120 seconds of rest in a 5-day resistance 
training routine. The LFRT performed a split-body routine, training each 
specific muscle group once a week. The HFRT performed a total-body routine, 
training all muscle groups every session and progressed from a training 
frequency of once per week to a training frequency of 5 times per week. Lean 
body mass increased without differences between groups (HFRT = 1.0 kg vs. LFRT = 
1.5 kg; p = 0.377). Similarly, 1RM increased without differences between groups 
(right LE, HFRT = 21.2 kg vs. LFRT = 19.7 kg, p = 0.782; BP, HFRT = 7.1 kg vs. 
LFRT = 4.5 kg, p = 0.293). These findings suggest that in young untrained men, 
progressing from a training frequency of once per week to a training frequency 
of 5 times per week with equated volume produces similar gains in LBM and muscle 
strength as a constant training frequency of once per week, over an 8-week 
training period.