The purpose of this study is to report a new and promising method for changing 
iris color in a sectorial heterochromia iridis patient. A 22-year-old man with a 
complaint of innate color disparity between his eyes presented to our clinic to 
seek medical advice. He underwent a comprehensive ophthalmic examination, 
including visual acuity, biomicroscopy, fundoscopy, intraocular pressure 
measurements, endothelial cell count, and evaluation of iridocorneal angle. The 
causes of acquired heterochromia were excluded. After a detailed explanation of 
the procedure and probable side effects, the patient underwent an application 
with a laser device that produces a frequency-doubled 532 nm wavelength Nd:YAG 
laser beam with a spot size of 400 μm (selective laser trabeculoplasty laser 
device). The heterochromic areas (brown) were divided into zones and a gradual 
treatment pattern was performed to avoid inflammation and flare. The patient 
showed no side effects such as increased intraocular pressure, pain, corneal 
edema, hypopyon formation, decrease in visual acuity, synechia, or iris defect. 
After two complete sessions, the color difference disappeared and a solid eye 
color was achieved.