The Currarino triad is a unique complex of congenital caudal anomalies, 
including anorectal malformation, sacral bony defect and presacral mass. This 
triad may be associated with Müllerian duct anomalies, such as duplication of 
the vagina and uterus. Each of these diseases has a familial tendency and 
sometimes coexist within families. But, when coexisting in familial cases, 
nearly all reported cases revealed mutations of the motor neuron and pancreas 
homeobox 1 (MNX1) gene. Familial cases of Currarino triad combined with 
Müllerian duct anomaly without MNX1 gene mutation are very rare. Here we report 
cases of mother and daughter, who had Currarino triad and Müllerian duct anomaly 
without MNX1 gene mutation, along with a brief literature review.