In addition to the typical manifestations of thrombotic-thrombocytopenic purpura 
like thrombocytopenia, haemolysis, fever, coma and renal failure, signs of a 
beginning DIC could be seen in a patient after abdominal surgery. Haemostatic, 
cardiovascular and respiratory data are presented. Pulmonary angiography by 
using a Swan-Ganz-catheter revealed multiple filling defects reversible with 
therapy. Treatment with fresh whole blood aggravated thrombocytopenia. Daily 
infusions of fresh frozen plasma combined with heparinisation and antithrombin 
III because of DIC, induced haematologic remission. Renal failure and cerebral 
symptoms could not be influenced. Diagnosis, monitoring and therapy are 
discussed.