For development and evaluation of methods for predicting the effects of 
variations, benchmark datasets are needed. Some previously developed datasets 
are available for this purpose, but newer and larger benchmark sets for benign 
variants have largely been missing. VariSNP datasets are selected from dbSNP. 
These subsets were filtered against disease-related variants in the ClinVar, 
UniProtKB/Swiss-Prot, and PhenCode databases, to identify neutral or 
nonpathogenic cases. All variant descriptions include mapping to reference 
sequences on chromosomal, genomic, coding DNA, and protein levels. The datasets 
will be updated with automated scripts on a regular basis and are freely 
available at http://structure.bmc.lu.se/VariSNP.