Edaravone (MCI-186) is a novel synthetic free radical scavenger intended to have 
neuroprotective effect against ischemic insult. It is currently used on patients 
with cerebral infarction. Here, we note beneficial pharmaceutical effects of 
edaravone in rat experimental traumatic brain injury. Under specific 
experimental conditions, edaravone minimized traumatic brain injury by 
functioning as a synthetic antioxidant. Clinical trials testing the efficacy of 
edaravone are warranted.