INTRODUCTION: Mild therapeutic hypothermia is an increasingly recognised 
treatment option to reduce perihemorrhagic edema in severe intracerebral 
hemorrhage.
CASE DESCRIPTION: We report the case of a 77-year old woman with atypical 
intracerebral hemorrhage that was treated with mild hypothermia in addition to 
osmotic therapy. The patient's urine subsequently showed a green discoloration. 
Urine discoloration was completely reversible upon discontinuation of propofol.
DISCUSSION AND EVALUATION: Propofol-related urine discoloration may have been 
provoked by hypothermia. Due to the benign nature of this side effect, propofol 
should be stopped and gastrointestinal function should be supported.
CONCLUSION: More studies are needed to show a causal role of hypothermia and 
related decreased enzymatic function.