Cryptococcus neoformans is an encapsulated yeast that can cause primary 
pulmonary infections or disseminate and cause infections of the central nervous 
system, meninges, skin, and bone in the immunocompromised host. We present here 
an unusual case of an immunocompetent patient who had laryngitis due to C. 
neoformans that mimicked a laryngeal carcinoma on clinical examination and 
imaging studies.