Author information:
(1)Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK. 
hcm@sanger.ac.uk jeff.barrett@genomicsplc.com.
(2)Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
(3)Great Ormond Street Hospital for Children, National Health Service (NHS) 
Foundation Trust, Great Ormond Street Hospital, Great Ormond Street, London WC1N 
3JH, UK.
(4)European Molecular Biology Laboratory-European Bioinformatics Institute, 
Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
(5)Department of Paediatrics, Cambridge University Hospitals NHS Foundation 
Trust, Cambridge, UK.
(6)Division of Cardiovascular Medicine, Radcliffe Department of Medicine, 
University of Oxford, Oxford, UK.
(7)Sheffield Clinical Genetics Service, Sheffield Children's NHS Foundation 
Trust, OPD2, Northern General Hospital, Herries Rd., Sheffield, S5 7AU, UK.
(8)Department of Genetics, Aberdeen Royal Infirmary, Aberdeen, UK.
(9)Wessex Clinical Genetics Service, G Level, Princess Anne Hospital, Coxford 
Road, Southampton SO16 5YA, UK.
(10)Cheshire and Merseyside Clinical Genetic Service, Liverpool Women's NHS 
Foundation Trust, Crown Street, Liverpool L8 7SS, UK.
(11)Department of Clinical Genetics, City Hospital Campus, Hucknall Road, 
Nottingham NG5 1PB, UK.
(12)Institute of Cancer and Genetics, University Hospital of Wales, Cardiff, UK.
(13)Temple Street Children's Hospital, Dublin, Ireland.
(14)Department of Clinical Genetics, Cambridge University Hospitals NHS 
Foundation Trust, Cambridge, UK.
(15)Clinical Genetics Unit, Birmingham Women's Hospital, Edgbaston, Birmingham 
B15 2TG, UK.
(16)Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Western 
Bank, Sheffield S10 2TH, UK.
(17)Northern Genetics Service, Newcastle upon Tyne Hospitals, NHS Foundation 
Trust, Newcastle upon Tyne, UK.
(18)Clinical Genetics, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.
(19)Department of Clinical Genetics, University Hospitals of Leicester NHS 
Trust, Leicester Royal Infirmary, Leicester LE1 5WW, UK.
(20)University of Exeter Medical School, Institute of Biomedical and Clinical 
Science, Research, Innovation, Learning and Development (RILD), Royal Devon and 
Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
(21)Medical Research Council (MRC) Human Genetics Unit, MRC Institute of 
Genetics and Molecular Medicine (IGMM), University of Edinburgh, Western General 
Hospital, Edinburgh EH4 2XU, UK.