We aimed this systematic review to analyze and review the currently available 
published literature related to long COVID, understanding its pattern, and 
predicting the long-term effects on survivors. We thoroughly searched the 
databases for relevant articles till May 2021. The research articles that met 
our inclusion and exclusion criteria were assessed and reviewed by two 
independent researchers. After preliminary screening of the identified articles 
through title and abstract, 249 were selected. Consequently, 167 full-text 
articles were assessed and reviewed based on our inclusion criteria and thus 20 
articles were regarded as eligible and analyzed in the present analysis. All the 
studies included adult population aged between 18 and above 60 years. The median 
length of hospital stay of the COVID-19 patients during the acute infection 
phase ranged from 8 days to 17 days. The most common prevalent long-term 
symptoms in COVID-19 patients included persistent fatigue and dyspnea in almost 
all of the studies. Other reported common symptoms included: shortness of 
breath, cough, joint pain, chest pain or tightness, headache, loss of 
smell/taste, sore throat, diarrhea, loss of memory, depression, anxiety. 
Associated cardiovascular events included arrhythmias, palpitations and 
hypotension, increased HR, venous thromboembolic diseases, myocarditis, and 
acute/decompensated heart failure as well. Among neurological manifestations 
headache, peripheral neuropathy symptoms, memory issues, concentration, and 
sleep disorders were most commonly observed with varying frequencies. Mental 
health issues affecting mental abilities, mood fluctuations namely anxiety and 
depression, and sleep disorders were commonly seen. Further, diarrhea, vomiting, 
digestive disorders, and Loss of appetite or weight loss are common 
gastrointestinal manifestations. Therefore, appropriate clinical evaluation is 
required in long COVID cases which in turn may help us to identify the risk 
factors, etiology, and to my help, we treat them early with appropriate 
management strategies.