In eukaryotic cells, non-translating mRNAs can accumulate into cytoplasmic mRNP 
(messenger ribonucleoprotein) granules such as P-bodies (processing bodies) and 
SGs (stress granules). P-bodies contain the mRNA decay and translational 
repression machineries and are ubiquitously expressed in mammalian cells and 
lower eukaryote species including Saccharomyces cerevisiae, Drosophila 
melanogaster and Caenorhabditis elegans. In contrast, SGs are only detected 
during cellular stress when translation is inhibited and form from aggregates of 
stalled pre-initiation complexes. SGs and P-bodies are related to NGs (neuronal 
granules), which are essential in the localization and control of mRNAs in 
neurons. Importantly, RNA granules are linked to the cytoskeleton, which plays 
an important role in mediating many of their dynamic properties. In the present 
review, we discuss how P-bodies, SGs and NGs are linked to cytoskeletal networks 
and the importance of these linkages in maintaining localization of their RNA 
cargoes.