Morgellons disease is a rare disease with unknown etiology. Herein, we report 
the first case of Morgellons disease in Korea. A 30-year-old woman presented 
with a 2-month history of pruritic erythematous patches and erosions on the 
arms, hands, and chin. She insisted that she had fiber-like materials under her 
skin, which she had observed through a magnifying device. We performed skin 
biopsy, and observed a fiber extruding from the dermal side of the specimen. 
Histopathological examination showed only mild lymphocytic infiltration, and 
failed to reveal evidence of any microorganism. The polymerase chain reaction 
for Borrelia burgdorferi was negative in her serum.