Two unrelated Mexican girls, aged 14 months and 6 years respectively, with 
Kaufman oculocerebrofacial syndrome, are reported. Both showed psychomotor 
retardation, microcephaly, blepharophimosis and delayed growth as the main 
features; the infant also presented preauricular tags and large clitoris. 
Comparative analysis with previous cases reveals a heterogeneous syndrome in 
which the micro-brachycephaly, the mongoloid slanted eyes with different 
anomalies, the micrognathia and the neonatal respiratory distress are the most 
typical characteristics of this mental retardation syndrome.