The HMMTOP transmembrane topology prediction server predicts both the 
localization of helical transmembrane segments and the topology of transmembrane 
proteins. Recently, several improvements have been introduced to the original 
method. Now, the user is allowed to submit additional information about segment 
localization to enhance the prediction power. This option improves the 
prediction accuracy as well as helps the interpretation of experimental results, 
i.e. in epitope insertion experiments.
AVAILABILITY: HMMTOP 2.0 is freely available to non-commercial users at 
http://www.enzim.hu/hmmtop. Source code is also available upon request to 
academic users.