SUMMARY: Molecular recognition features (MoRFs) are small, intrinsically 
disordered regions in proteins that undergo a disorder-to-order transition on 
binding to their partners. MoRFs are involved in protein-protein interactions 
and may function as the initial step in molecular recognition. The aim of this 
work was to collect, organize and store all membrane proteins that contain 
MoRFs. Membrane proteins constitute ∼30% of fully sequenced proteomes and are 
responsible for a wide variety of cellular functions. MoRFs were classified 
according to their secondary structure, after interacting with their partners. 
We identified MoRFs in transmembrane and peripheral membrane proteins. The 
position of transmembrane protein MoRFs was determined in relation to a 
protein's topology. All information was stored in a publicly available mySQL 
database with a user-friendly web interface. A Jmol applet is integrated for 
visualization of the structures. mpMoRFsDB provides valuable information related 
to disorder-based protein-protein interactions in membrane proteins.
AVAILABILITY: http://bioinformatics.biol.uoa.gr/mpMoRFsDB