Large intergenic noncoding (linc) RNAs constitute a new dimension of 
posttranscriptional gene regulation. In this issue of Developmental Cell, Wang 
et al. (2013) find that linc-RoR maintains human embryonic stem cell 
self-renewal by functioning as a sponge to trap miR-145, thus regulating core 
pluripotency factors Oct4, Nanog, and Sox2.