Kikuchi's disease (KD) is a benign and self-limiting lymphadenitis, particularly 
affecting young women. KD is often associated with fever, arthralgia, and 
leukopenia, features also found in systemic lupus erythematosus (SLE). 
Lymphadenitis associated with SLE is indistinguishable from that in KD, and the 
association of KD and SLE has been previously reported. We describe a case of KD 
who developed a typical butterfly rash, reminiscent of SLE. However, 
histological and laboratory findings excluded the diagnosis of SLE. This case 
emphasizes that careful differential diagnosis between KD and SLE is required.