Frequency of INherited Disorders database (FIND base; http://www.findbase.org) 
records frequencies of causative genetic variations worldwide. Database records 
include the population and ethnic group or geographical region, the disorder 
name and the related gene, accompanied by links to any related external 
resources and the genetic variation together with its frequency in that 
population. In addition to the regular data content updates, we report the 
following significant advances: (i) the systematic collection and thorough 
documentation of population/ethnic group-specific pharmacogenomic markers allele 
frequencies for 144 markers in 14 genes of pharmacogenomic interest from 
different classes of drug-metabolizing enzymes and transporters, representing 
150 populations and ethnic groups worldwide; (ii) the development of new data 
querying and visualization tools in the expanded FINDbase data collection, built 
around Microsoft's PivotViewer software (http://www.getpivot.com), based on 
Microsoft Silverlight technology (http://www.silverlight.net) that facilitates 
querying of large data sets and visualizing the results; and (iii) the 
establishment of the first database journal, by affiliating FINDbase with Human 
Genomics and Proteomics, a new open-access scientific journal, which would serve 
as a prime example of a non-profit model for sustainable database funding.