Malignant gastointestinal stromal tumors (M-GIST) are rare mesenchymal tumors 
that arise in the wall of the gastrointestinal (GI) tract. Small intestinal GIST 
account for approximately 35% of all GIST the diagnosis of these tumors is 
difficult to establish, because the symptoms are vague and non-specific and 
traditional endoscopy is commonly unsatisfactory. Because of the infrequent 
nature of malignant small bowel tumors, the natural history and factors 
affecting outcome remain poorly defined; stage at presentation and complete 
surgical resection seem to be the main prognostic factors. For these rare 
tumors, surgery remains the treatment of choice, with little efficacy reported 
for irradiation, chemiotherapy, or both. Two cases of GIST of the jejunum, 
complicated by intestinal bleeding and intestinal obstruction respectively, are 
presented and a review of the literature is made.