Overgrowth syndromes such as Beckwith-Wiedemann syndrome, Sotos syndrome, and 
Weaver syndrome have an increased risk of neoplasia. Two previous cases of 
neuroblastoma have been reported in children with Weaver syndrome. We present a 
third description of a patient with Weaver syndrome and neuroblastoma. In a 
child with phenotypic characteristics consistent with Weaver syndrome, 
evaluation for neuroblastoma should be considered.