BACKGROUND: Intracranial infantile hemangiomas are extremely rare, with only 36 
patients reported in literature. Treatment for intracranial infantile 
hemangiomas has been mostly limited to surgery, steroids, and interferon 
therapy. Propranolol, which is often used to treat cutaneous infantile 
hemangiomas, is not currently standard treatment for intracranial infantile 
hemangiomas.
PATIENT DESCRIPTION: We present a one-month old boy with an intracranial 
infantile hemangioma treated with propranolol.
RESULTS: This boy was being treated with oral propranolol for a supraclavicular 
infantile hemangioma. Subsequent brain magnetic resonance imaging (MRI) scan 
showed evidence of an associated intracranial infantile hemangioma in the right 
cerebellopontine angle. Repeat brain MRI scan after two months of propranolol 
treatment demonstrated a significant reduction in the size of the intracranial 
infantile hemangioma.
CONCLUSIONS: This is the first report of successful therapy of an intracranial 
infantile hemangioma with propranolol.