The Madeline 2.0 Pedigree Drawing Engine (PDE) is a pedigree drawing program for 
use in linkage and family-based association studies. The program is designed to 
handle large and complex pedigrees with an emphasis on readability and 
aesthetics. For complex pedigrees, we use a hybrid algorithm in which 
consanguinous loops are drawn as cyclic graphs whenever possible, but we resort 
to acyclic graphs when matings can no longer be connected without line 
crossings. A similar hybrid approach is used to avoid line crossings for matings 
between distant descendants of different founding groups. Written in 
object-oriented C++ and released under the GNU General Public License (GPL), 
Madeline 2.0 PDE reads input files specified on the command line and generates 
pedigree drawings without user interaction. Pedigree output in scalable vector 
graphics (SVG) format can be viewed in browsers with native SVG rendering 
support or in vector graphics editors. We provide an easy-to-use public web 
service, which is experimental and still under development.
AVAILABILITY: http://kellogg.umich.edu/madeline.