We tested the effect of two different concentrations (150μg/l and 0.15μg/l) of 
mycotoxin zearalenone (ZEA) on the reproductive parameters and expression of 
testicular genes in male mice. In adult males, no reduction of body or 
reproductive organ weight was observed, and the seminiferous tubules were 
morphologically normal with ongoing spermatogenesis. However, we found decreased 
sperm concentration, increase of morphologically abnormal spermatozoa and 
increased binding of apoptotic marker annexin V. This study was also focused on 
the evaluation of gene expression profiles of 28 genes playing important roles 
during the processes occurring in the testicular tissue. We detected changes in 
the expression of genes important for proper spermatogenesis. Surprisingly, we 
observed a stronger effect after exposure to the lower dose of ZEA.