We present the case of a preterm 6-month-old African American infant who 
developed craniosynostosis secondary to rickets. This child developed rickets 
and macrocephaly by the age of 6 months. His head continued to enlarge, and a 3D 
CT obtained when the child was 2 years old revealed metopic and bilateral 
coronal craniosynostosis. This CT suggested increased intracranial pressure, and 
therefore, corrective cranial vault reconstruction was performed. 
Craniosynostosis secondary to rickets is rarely reported, but since neither 
rickets nor craniosynostosis is a reportable disease, the exact incidence of 
both diseases is unknown. Craniosynostosis should be suspected in any rachitic 
child with an abnormal head circumference or shape and craniofacial CT 
evaluation should be performed, so that a corrective surgery can be performed at 
an appropriate age.