Anterograde amnesia, possibly accompanied by acute brain syndrome, is a 
potential side-effect of certain benzodiazepines, particularly triazolam. 
Flumazenil is a benzodiazepine antagonist that is highly effective in reversing 
the central nervous system effects of benzodiazepine overdose. We report a case 
of triazolam overdose resulting in anterograde amnesia after flumazenil 
administration had restored clear consciousness. The defect in memory may have 
been due to too little flumazenil being given or failure of memory consolidation 
affected by the character of triazolam during the induced lucent period. We feel 
that physicians should be aware of the potential occurrence of acute brain 
syndrome in patients with benzodiazepine overdose despite treatment with 
flumazenil.