Although glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common 
enzyme disorder worldwide, it has rarely been reported among Korean. The patient 
was previously healthy 39 yr old male who showed severe hemolytic anemia and 
acute renal failure accompanied by hyperbilirubinemia after hepatitis A 
infection. The additional studies for differential diagnosis of hemolytic anemia 
showed a moderate deficiency of G6PD enzyme. Because hepatitis A infection in 
patient with G6PD deficiency present much more severe clinical symptoms, G6PD 
enzyme should be examined in patients with triggering factors of hemolysis such 
as hepatitis A infection.