Autism Spectrum Disorders (ASD) are characterized by: social and communication 
impairments, and by restricted repetitive behaviors. The aim of the present 
paper is to review abnormalities of oxytocin (OXT) and related congenital 
malformations in ASD. A literature search was conducted in the PubMed database 
up to 2016 for articles related to the pathomechanism of ASD, abnormalities of 
OXT and the OXT polymorphism in ASD. The pathomechanism of ASD has yet to be. 
The development of ASD is suggested to be related to abnormalities of the 
oxytocin-arginin-vasopressin system. Previous results suggest that OXT and 
arginine vasopressin (AVP) may play a role in the etiopathogenesis of ASD.