In view of earlier reports in the literature it was tried to use TRH 
(thyrotropin releasing hormone) in cases of amyotrophic lateral sclerosis. TRH 
was given during 3 weeks once daily intravenously in drip infusions in a 0.4 mg 
dose. For objectivization of the results the muscle power was assessed using a 
five-grade scale of Lovette. TRH effect on EMG was analysed also. It was found 
that in only 3 out of 14 patients with moderately progressed disease no 
improvement was achieved, while in 11 cases the improvement was from 10 to 20%. 
However, the improvement was transient, and TRH treatment failed to stop the 
progression of the disease.