Considering the high mortality rates and the unfavorable prognosis of gastric 
cancer (GC) as well as the lack of a clinical predictive marker, which is 
sufficiently sensitive to GC, it is of great significance to investigate new 
sensitive and specific markers for GC diagnosis. MicroRNAs (miRNAs) could be a 
practical form of potential biomarkers in the diagnosis of human disease, and 
they are confirmed to be closely associated with GC. In this review, we discuss 
the recent research results that indicate the feasibility and clinical 
applications of miRNAs in GC. Although several challenges remain to be 
addressed, miRNAs have the potential to be applied in the diagnosis of GC.