INTRODUCTION. It has been shown that inflammation affects thyroid function. In 
patients with end-stage renal disease, low plasma triiodothyronine (T3) may be 
an unsuspected expression of the inflammatory state of these patients. This 
study evaluated the correlation between T3 and high-sensitivity C-reactive 
protein (HSCRP) levels in patients on peritoneal dialysis (PD) and hemodialysis. 
MATERIALS AND METHODS. This is a cross-sectional study aiming at the correlation 
between T3 and HSCRP levels among 30 patients on PD, 30 patients on 
hemodialysis, and 20 healthy individuals. Serum levels of HSCRP, T3, thyroxine 
(T4), thyroid stimulating hormone, T3 resin uptake, and free T3 index (FT3I) and 
free T4 index (FT4I) were compared between the three groups. RESULTS. There were 
no significant differences between hemodialysis and PD patients in respect to 
T3, T4, FT3I, and FT4I. In PD and hemodialysis patients, T3 and FT3I were lower 
than in controls (P < .001), but there was no significant difference between PD 
and hemodialysis patients. T3 resin uptake and thyroid stimulating hormone 
differed significantly between PD and hemodialysis patients. There was a 
significant inverse correlation between HSCRP and T3 and FT3I among hemodialysis 
patients (P = .04); however, there was no such correlations in PD patients. 
CONCLUSIONS. The relationship between T3 and HSCRP suggests that inflammation 
might be involved in the low T3 syndrome in hemodialysis patients, but we did 
not find a significant correlation between T3 and HSCRP levels in patients on 
peritoneal dialysis.