Burning Mouth Syndrome (BMS) is a frequent disease characterized by a burning or 
painful sensation in the tongue and/or other oral sites without clinical mucosal 
abnormalities or lesions. The etiopathology is unknown although local, systemic 
and psychological factors have been connected with BMS. As this syndrome is a 
multifactorial disease, the diagnostic and therapeutic approach should be 
multidisciplinary. In this paper a review of the literature is presented and the 
most recent advancement on clinical, etiologic, diagnostic and therapeutic 
aspects of BMS are discussed.