Some patients developed Guillain-Barré syndrome after the administration of 
bovine brain ganglioside. Patients with Guillain-Barré syndrome subsequent to 
Campylobacter jejuni enteritis frequently have IgG antibody to GM1 ganglioside. 
Miller Fisher syndrome, a variant of Guillain-Barré syndrome, is associated with 
IgG antibody to GQ1b ganglioside. My colleagues and I showed the existence of 
molecular mimicry between GM1 and lipopolysaccharide of C. jejuni isolated from 
a patient with Guillain-Barré syndrome, and that between GQ1b and C. jejuni 
lipopolysaccharides from patients with Miller Fisher syndrome. The glycotope 
mimicry between infectious agents and gangliosides may function in the 
production of antiganglioside antibodies and the development of Guillain-Barré 
syndrome and Miller Fisher syndrome.