Parkinson's disease is a disabling and progressive neurological condition 
characterized by multiple motor and non motor symptoms that contribute to 
deterioration in quality of life. The diversity of symptoms associated with the 
disease and its management affect the patients on their physical, social and 
mental quality of life. The aim of this study was to identify key dimensions of 
health related quality of life (HRQOL) in a population affected with Parkinson's 
disease with a degree of mild-moderate impairment. Thirty six patients with 
Parkinson were recruited. The Hoehn and Yarh scale, the Unified Parkinson's 
Disease Rate Scale, the scale of activities of daily life and Schwab & England 
Get Up & Go Test were applied. HRQOL was assessed with the EuroQol-5D and the 
specific questionnaire Parkinson's Disease Questionnaire-39 items. The 
dimensions of the PDQ-39, except the PDQ-39 Pain domain and the EuroQol-5D 
correlated significantly with the severity of the disease. HRQOL was correlated 
with the functional status of patients. Only the PDQ-39 pain domain correlated 
with the risk of falls. Our results suggest that the HRQOL of patients with PD, 
in a state of mild-moderate impairment, is strongly influenced by disease 
severity and functional status.