Lemierre's syndrome is a rare clinical condition that generally develops 
secondary to oropharyngeal infection caused by Fusobacterium necrophorum, which 
is an anaerobic bacteria. A 62-year-old patient with diabetes mellitus presented 
with internal jugular vein and sigmoid sinus-transverse sinus thrombophlebitis, 
accompanying otitis media and mastoiditis that developed after an upper airway 
infection. Interestingly, there were air bubbles in both the internal jugular 
vein and transverse sinus. Vancomycin and meropenem were started and a right 
radical mastoidectomy was performed. The patient's clinical picture completely 
resolved in 14 days. High mortality and morbidity may be prevented with a prompt 
diagnosis of Lemierre's syndrome.