Wilson's disease (WD), or hepatolenticular degeneration, is an autosomal 
recessive inheritance disorder of copper metabolism caused by ATP7B gene 
mutation. As WD is an inherited disease of the nervous system that is not 
curable; early diagnosis with early and life-long treatment leads to better 
prognoses. Currently, the recommended treatment for WD is integrated Chinese and 
Western medicine. A number of studies indicate that treatment of integrative 
medicine can not only enforce the de-copper effect but also improve liver 
function, intelligence, and other factors. This article reviewed in detail the 
advantages of WD treated with Chinese and Western medicine together.