BACKGROUND: Burning mouth syndrome (BMS) is common conditions that affects 
menopause women, patients suffer from sever burning sensation. Up to now there 
is no definitive treatment for this disease. Present study was undertaken to 
evaluate the efficacy of low-level laser (LLL) in improving the symptoms of 
burning mouth syndrome.
MATERIAL AND METHODS: Twenty patients with BMS were enrolled in this study; they 
were divided in two groups randomly. In the laser group, in each patient, 10 
areas on the oral mucosa were selected and underwent LLL irradiation at a 
wavelength of 630 nm, and a power of 30 mW for 10 seconds twice a week for 4 
weeks. In the placebo group, silent/off laser therapy was carried out during the 
same period in the same areas. Burning sensation and quality of life were 
evaluated.
RESULTS: Burning sensation severity and quality of life in the two groups after 
intervention were different significant statistically, (p= 0.004, p= 0.01 
respectively) .Patients in laser group had better results.
CONCLUSIONS: It can be concluded that low level laser might decrease the 
intensity of burning mouth syndrome.
KEY WORDS: Pain, low-level laser, burning mouth syndrome, oral mucosa.