Carpel tunnel syndrome (CTS) is a condition in which median nerve compression 
results in paresthesias and pain in the wrist and hand. We are going to report a 
rare case of topiramate-induced neuropathy which clinically resembles CTS. 
Discontinuation of topiramate resulted in spontaneous resolution of numbness, 
paresthesia and pain in a few days. High clinical suspicion is advised in 
patients who are on topiramate and present with signs of compressive neuropathy. 
Level of evidence: V.