Secondary dystonia encompasses a heterogeneous group with different etiologies. 
Cerebral palsy is the most common cause. Pharmacological treatment is often 
unsatisfactory. There are only limited data on the therapeutic outcomes of deep 
brain stimulation in dyskinetic cerebral palsy. The published literature 
regarding deep brain stimulation and secondary dystonia was reviewed in a 
meta-analysis to reevaluate the effect on cerebral palsy. The Burke-Fahn-Marsden 
Dystonia Rating Scale movement score was chosen as the primary outcome measure. 
Outcome over time was evaluated and summarized by mixed-model repeated-measures 
analysis, paired Student t test, and Pearson's correlation coefficient. Twenty 
articles comprising 68 patients with cerebral palsy undergoing deep brain 
stimulation assessed by the Burke-Fahn-Marsden Dystonia Rating Scale were 
identified. Most articles were case reports reflecting great variability in the 
score and duration of follow-up. The mean Burke-Fahn-Marsden Dystonia Rating 
Scale movement score was 64.94 ± 25.40 preoperatively and dropped to 50.5 ± 
26.77 postoperatively, with a mean improvement of 23.6% (P < .001) at a median 
follow-up of 12 months. The mean Burke-Fahn-Marsden Dystonia Rating Scale 
disability score was 18.54 ± 6.15 preoperatively and 16.83 ± 6.42 
postoperatively, with a mean improvement of 9.2% (P < .001). There was a 
significant negative correlation between severity of dystonia and clinical 
outcome (P < .05). Deep brain stimulation can be an effective treatment option 
for dyskinetic cerebral palsy. In view of the heterogeneous data, a prospective 
study with a large cohort of patients in a standardized setting with a 
multidisciplinary approach would be helpful in further evaluating the role of 
deep brain stimulation in cerebral palsy. © 2013 Movement Disorder Society.