SUMMARY: Rtpca is an R package implementing methods for inferring 
protein-protein interactions (PPIs) based on thermal proteome profiling 
experiments of a single condition or in a differential setting via an approach 
called thermal proximity coaggregation. It offers user-friendly tools to explore 
datasets for their PPI predictive performance and easily integrates with 
available R packages.
AVAILABILITY AND IMPLEMENTATION: Rtpca is available from Bioconductor 
(https://bioconductor.org/packages/Rtpca).
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics 
online.