The LINCS L1000 data repository contains almost two million gene expression 
profiles for thousands of small molecules and drugs. However, due to the 
complexity and the size of the data repository and a lack of an interoperable 
interface, the creation of pharmacologically meaningful workflows utilizing 
these data is severely hampered. In order to overcome this limitation, we 
developed the L1000 Viewer, a search engine and graphical web interface for the 
LINCS data repository. The web interface serves as an interactive platform 
allowing the user to select different forms of perturbation profiles, e.g., for 
specific cell lines, drugs, dosages, time points and combinations thereof. At 
its core, our method has a database we created from inferring and utilizing the 
intricate dependency graph structure among the data files. The L1000 Viewer is 
accessible via http://L1000viewer.bio-complexity.com/.