Patau syndrome is a chromosomal disorder associated with multiple malformations 
caused by inheritance of an extra chromosome (trisomy 13). Some skin defects 
have been reported in patients with Patau syndrome, such as scalp defects, 
glabellar stains, deep palmar creases, rocker-bottom feet, convex soles, 
hyperconvextity of the nails, and multiple hemangiomas. To our knowledge, 
widespread comedonal and cystic acne have not been previously reported in Patau 
syndrome.