We present LaTcOm, a new web tool, which offers several alternative methods for 
'rare codon cluster' (RCC) identification from a single and simple graphical 
user interface. In the current version, three RCC detection schemes are 
implemented: the recently described %MinMax algorithm and a simplified sliding 
window approach, along with a novel modification of a linear-time algorithm for 
the detection of maximally scoring subsequences tailored to the RCC detection 
problem. Among a number of user tunable parameters, several codon-based scales 
relevant for RCC detection are available, including tRNA abundance values from 
Escherichia coli and several codon usage tables from a selection of genomes. 
Furthermore, useful scale transformations may be performed upon user request 
(e.g. linear, sigmoid). Users may choose to visualize RCC positions within the 
submitted sequences either with graphical representations or in textual form for 
further processing.
AVAILABILITY: LaTcOm is freely available online at the URL 
http://troodos.biol.ucy.ac.cy/latcom.html.