OBJECTIVE: Behcet's disease is a multisystem inflammatory disorder, and its 
etiology has not been defined clearly yet. In this study, we aimed to 
investigate the antistreptolysin O (ASO) levels of patients with Behcet's 
disease.
MATERIALS AND METHODS: Thirty patients with Behcet's disease and 30 healthy 
controls were enrolled in this study. We measured erythrocyte sedimentation rate 
(ESR), serum C-reactive protein (CRP), and ASO levels in both groups.
RESULTS: There was no statistically significant difference between the two 
groups with respect to demographic data (p>0.05). The ASO levels of the patients 
and the controls were 288.4±145.7 and 170.6±142.4 ng/ml, respectively. In the 
patients with Behcet's disease, ASO (p<0.01) and ESR (p<0.05) values were 
significantly higher than in the healthy controls. There was no other 
significant difference in serum CRP levels between the patients and the 
controls. We could not find any correlation among ASO, CRP, and ESR values.
CONCLUSION: Our results suggest that serum ASO levels may increase in patients 
with Behcet's disease. Further studies are needed in order to define the 
relationship between ASO levels and inflammation status in Behcet's disease.