The aim of this study was to evaluate the clinical, laboratory findings and 
therapeutic features of patients with brucellosis. The diagnosis was made by 
clinical findings, automated blood culture, serology (Rose Bengal plate 
agglutination test, standard tube agglutination (Wright) and 
immunofluorerescence). The susceptibility of 13 strains was tested in vitro. The 
base sequence was determined for four strains. Forty-five cases were collected 
(31 acute and 14 sub-acute). Contamination was digestive in 62%. Symptoms of 
patients were fever (93%), sweating (82%), arthralgia (78%) and splenomegaly 
(51%). Elevated erythrocyte sedimentation rate was determined in 80%, leukopenia 
in 49% and anaemia in 37% of cases. Blood cultures were positives in 39% of 
cases. The four sequenced strains were identified as Brucella melitensis biovar 
abortus. Six strains were resistant to sufomethoxazol-trimetoprim (54%). In 93% 
of cases, the treatment was associated rifampicin and doxycyclin. One patient 
died. No relapse was reported.