LncRNAs are involved in the occurrence and progressions of multiple cancers. 
Emerging evidence has shown that PCAT6, a newly discovered carcinogenic lncRNA, 
is abnormally elevated in various human malignant tumors. Until now, PCAT6 has 
been found to sponge various miRNAs to activate the signaling pathways, which 
further affects tumor cell proliferation, migration, invasion, cycle, apoptosis, 
radioresistance, and chemoresistance. Moreover, PCAT6 has been shown to exert 
biological functions beyond ceRNAs. In this review, we summarize the biological 
characteristics of PCAT6 in a variety of human malignancies and describe the 
biological mechanisms by which PCAT6 can facilitate tumor progression. Finally, 
we discuss its diagnostic and prognostic values and clinical applications in 
various human malignancies.