Melioidosis is caused by the environmental bacterium Burkholderia pseudomallei 
and can present with severe sepsis. Predisposing risk factors are present in 80% 
of cases. Monoclonal antibodies are increasingly prescribed for varied medical 
conditions. This report describes the first known case of melioidosis in a 
patient whose only risk factor for disease is treatment with a monoclonal 
antibody. Prescribers of monoclonal antibodies and other immunosuppressants 
should ensure that their patients are aware of the potential risk of melioidosis 
prior to travel and the precautions that should be taken.