BACKGROUND: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, 
and skin changes (POEMS) syndrome is an uncommon condition related to a 
paraneoplastic syndrome secondary to an underlying plasma cell disorder. Among 
the myriad of manifestations of the disease, ocular signs and symptoms are 
relatively prevalent, affecting about half of all patients with the disease.
OBJECTIVE: To report the ocular manifestations of POEMS syndrome.
CASE: A 47-year-old lady diagnosed to have POEMS syndrome presented with 
painless progressive visual diminution. Her color vision was impaired. There was 
bilateral papilloedema.
CONCLUSION: POEMS syndrome should be considered among the differential diagnoses 
of all patients with a bilateral papilledema in which no other cause can be 
readily elucidated.