Reduced function of the thyroid gland causes Hypothyroidism which is further 
attributed to defects in the secretion of thyroid hormones triiodothyronine (T3) 
and tetra-iodothyronine or thyroxine (T4). T3 and T4 hormones are not only known 
to regulate the rate of metabolism but also affect the growth and rate of 
function of many other systems in the body such as neuromuscular, 
gastrointestinal and cardiovascular system. Hypothyroidism patient usually show 
higher levels of total cholesterol, low-density lipoproteins (LDL), 
triglycerides, and other lipid molecules associated with heart disease. The 
question still remained to be addressed though is whether hypothyroidism affects 
heart and result in cardiovascular disease. The current review updates us with 
the recent progress in the hypothyroidism area especially in relation to its 
connecting link with the heart disease. The present study will further enhance 
our understanding of the intricacies involved in the secretion of thyroid 
hormones (T3 & T4) and thyroid stimulating hormone (TSH) subsequently affecting 
serum lipid levels. The study may help to dice-out cardiovascular risk factors 
associated with hypothyroidism so that effective measures could be taken prior 
to occurrence of coronary heart disease.