Gardner-Diamond syndrome (GDS) is an uncommon disease clinically characterized 
by a wide spectrum of psycho-emotive symptoms associated with painful 
ecchymoses/purpuric lesions and positivity of auto-erythrocyte sensitization 
skin test. Herein, a perspective clinical and psychological observation of an 
adolescent GDS is firstly reported focusing on her psychological features 
long-term monitored for a 1-year period. The administration of a standardized 
tools battery allowed us to define psychological features of the young patient 
over time and to monitored clinical course and response to treatment.