Infection of the central nervous system due to Listeria monocytogenes is 
uncommon. The treatment of choice is ampicillin. We describe in this report a 
case of rhombencephalitis caused by Listeria monocytogenes successfully treated 
with linezolid. To the best of our knowledge, this is the first case in which 
linezolid was used to treat infection of the central nervous system caused by 
this organism.