Large numbers of long RNAs with little or no protein-coding potential [long 
noncoding RNAs (lncRNAs)] are being identified in eukaryotes. In parallel, 
increasing data describing the expression profiles, molecular features and 
functions of individual lncRNAs in a variety of systems are accumulating. To 
enable the systematic compilation and updating of this information, we have 
developed a database (lncRNAdb) containing a comprehensive list of lncRNAs that 
have been shown to have, or to be associated with, biological functions in 
eukaryotes, as well as messenger RNAs that have regulatory roles. Each entry 
contains referenced information about the RNA, including sequences, structural 
information, genomic context, expression, subcellular localization, 
conservation, functional evidence and other relevant information. lncRNAdb can 
be searched by querying published RNA names and aliases, sequences, species and 
associated protein-coding genes, as well as terms contained in the annotations, 
such as the tissues in which the transcripts are expressed and associated 
diseases. In addition, lncRNAdb is linked to the UCSC Genome Browser for 
visualization and Noncoding RNA Expression Database (NRED) for expression 
information from a variety of sources. lncRNAdb provides a platform for the 
ongoing collation of the literature pertaining to lncRNAs and their association 
with other genomic elements. lncRNAdb can be accessed at: 
http://www.lncrnadb.org/.