Author information:
(1)Abramson Cancer Center, Perelman School of Medicine at the University of 
Pennsylvania, Philadelphia2Center for Clinical Epidemiology and Biostatistics, 
Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
(2)Center for Clinical Epidemiology and Biostatistics, Perelman School of 
Medicine at the University of Pennsylvania, Philadelphia.
(3)Centre de Recherche en Cancérologie de Lyon, UMR Inserm, Centre Léon Bérard, 
Lyon, France.
(4)Department of Genetics and Computational Biology, Queensland Institute of 
Medical Research, Brisbane, Australia.
(5)Centre for Cancer Genetic Epidemiology, Department of Public Health and 
Primary Care, University of Cambridge, Cambridge, United Kingdom.
(6)Abramson Cancer Center, Perelman School of Medicine at the University of 
Pennsylvania, Philadelphia6Department of Medicine, Perelman School of Medicine 
at the University of Pennsylvania, Philadelphia.
(7)Sheba Medical Center, Tel Aviv, Israel.
(8)Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel Hashomer, 
Israel.
(9)Oncology Institute, Sheba Medical Center, Tel Hashomer, Israel.
(10)Oncology Institute, Rivkah Ziv Medical Center Zefat, Israel.
(11)Department of Oncology, Lund University, Lund, Sweden12Department of 
Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
(12)Division of Clinical Genetics, Department of Clinical and Experimental 
Medicine, Linköping University, Linköping, Sweden.
(13)Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden.
(14)Department of Oncology, Lund University, Lund, Sweden.
(15)Department of Clinical Genetics, Karolinska University Hospital, Stockholm, 
Sweden.
(16)Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden.
(17)Center for Clinical Cancer Genetics and Global Health, University of Chicago 
Medical Center, Chicago, Illinois.
(18)UCLA Schools of Medicine and Public Health, Division of Cancer Prevention 
and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, 
California.
(19)Department of Medicine and Genetics, University of California, San 
Francisco.
(20)Cancer Risk Program, Helen Diller Family Cancer Center, University of 
California, San Francisco.
(21)Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, 
New York.
(22)Department of Preventive Medicine, Keck School of Medicine, University of 
Southern California, Los Angeles.
(23)University of Texas MD Anderson Cancer Center, Houston.
(24)Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, 
Victoria, Australia 25Sir Peter MacCallum Department of Oncology, University of 
Melbourne, Melbourne, Australia.
(25)Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, 
Cedars-Sinai Medical Center, Los Angeles, California.
(26)Department of Pathology and Laboratory Medicine, University of Kansas 
Medical Center, Kansas City.
(27)Fox Chase Cancer Center, Philadelphia, Pennsylvania.
(28)Department of Health Research and Policy, Stanford University School of 
Medicine, Stanford, California.
(29)Department of Epidemiology, Cancer Prevention Institute of California, 
Fremont.
(30)Dana-Farber Cancer Institute, Boston, Massachusetts.
(31)Department of Epidemiology, Columbia University, New York, New York.
(32)Departments of Pediatrics and Medicine, Columbia University, New York, New 
York.
(33)Department of Dermatology, University of Utah School of Medicine, Salt Lake 
City.
(34)Department of Oncological Sciences, Huntsman Cancer Institute, University of 
Utah School of Medicine, Salt Lake City.
(35)Vilnius University Hospital Santariskiu Clinics, Hematology, Oncology, and 
Transfusion Medicine Center, Department of Molecular and Regenerative Medicine, 
State Research Institute Innovative Medicine Center, Vilnius, Lithuania.
(36)Latvian Biomedical Research and Study Centre, Riga, Latvia.
(37)Department of Medical Oncology, Beth Israel Deaconess Medical Center, 
Boston, Massachusetts.
(38)Department of Genetics, University of Pretoria, Pretoria, South Africa.
(39)Department of Population Sciences, Beckman Research Institute of City of 
Hope, Duarte, California.
(40)Departments of Oncology or Clinical Genetics, Rigshospitalet, Copenhagen 
University Hospital, Copenhagen, Denmark.
(41)Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, 
Copenhagen, Denmark.
(42)Oncology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
(43)Human Genetics Group, Spanish National Cancer Centre (CNIO), and Biomedical 
Network on Rare Diseases (CIBERER), Madrid, Spain.
(44)Human Genetics Group and Genotyping Unit, Spanish National Cancer Centre 
(CNIO), and Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain.
(45)Hospital clinico Universitario "Lozano Blesa," Instituto de investigación 
sanitaria de Aragón (IIS), Zaragoza, Spain.
(46)Molecular Genetics Laboratory (Department of Genetics), Cruces University 
Hospital Barakaldo, Bizkaia, Spain.
(47)Institute of Biology and Molecular Genetics. Universidad de Valladolid 
(IBGM-UVA), Valladolid, Spain.
(48)Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community 
Research Network, Duarte, California.
(49)Unit of Genetic Counselling, Medical Oncology Department, Istituto Nazionale 
Tumori Regina Elena, Rome, Italy.
(50)Department of Medical Science, University of Turin, and AO Città della 
Salute e della Scienza, Turin, Italy.
(51)Unit of Medical Genetics, Department of Preventive and Predictive Medicine, 
Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
(52)Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, 
Milan, Italy.
(53)AO Città della Salute e della Scienza, Turin, Italy.
(54)Department of Molecular Medicine, University La Sapienza, Rome, Italy.
(55)Department of Experimental Oncology, Istituto Europeo di Oncologia, Milan, 
Italy57Cogentech Cancer Genetic Test Laboratory, Milan, Italy.
(56)Institute of Medical Genetics, Catholic University, "A. Gemelli" Hospital, 
Rome, Italy.
(57)Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of 
Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori 
(INT), Milan, Italy60IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, 
Milan, Italy.
(58)Cancer Bioimmunotherapy Unit, Centro di Riferimento Oncologico, IRCCSCRO 
Aviano National Cancer Institute, Aviano (PN), Italy.
(59)Cogentech Cancer Genetic Test Laboratory, Milan, Italy60IFOM, Fondazione 
Istituto FIRC di Oncologia Molecolare, Milan, Italy.
(60)Unit of Hereditary Cancer, IRCCS AOU San Martino-IST Istituto Nazionale per 
la Ricerca sul Cancro, Genoa, Italy.
(61)Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific 
Research "Demokritos" Aghia Paraskevi Attikis, Athens, Greece.
(62)Instituto de Genética Humana, Pontificia Universidad Javeriana, Bogotá, 
Colombia65Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum 
(DKFZ), Heidelberg, Germany.
(63)Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum 
(DKFZ), Heidelberg, Germany 66Department of Basic Sciences, Shaukat Khanum 
Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan.
(64)Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum 
(DKFZ), Heidelberg, Germany.
(65)Genetic Medicine, Manchester Academic Health Sciences Centre, Central 
Manchester University Hospitals, NHS Foundation Trust, Manchester, United 
Kingdom.
(66)Oncogenetics Team, Institute of Cancer Research and Royal Marsden, NHS 
Foundation Trust, London, United Kingdom.
(67)Ferguson-Smith Centre for Clinical Genetics, Yorkhill Hospitals, Glasgow, 
United Kingdom.
(68)Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, 
United Kingdom.
(69)West Midlands Regional Genetics Service, Birmingham Women's Hospital 
Healthcare NHS Trust, Edgbaston, Birmingham, United Kingdom.
(70)Sheffield Clinical Genetics Service, Sheffield Children's Hospital, 
Sheffield, United Kingdom.
(71)Department of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter, 
United Kingdom.
(72)Clinical Genetics Department, St Georges Hospital, University of London, 
United Kingdom.
(73)Northern Ireland Regional Genetics Centre, Belfast City Hospital, Belfast, 
United Kingdom.
(74)Oxford Regional Genetics Service, Churchill Hospital, Oxford, United 
Kingdom.
(75)South East of Scotland Regional Genetics Service, Western General Hospital, 
Edinburgh, United Kingdom.
(76)Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin and 
St James's Hospital, Dublin, Eire.
(77)South East Thames Regional Genetics Service, Guy's Hospital London, United 
Kingdom.
(78)Yorkshire Regional Genetics Service, Leeds, United Kingdom.
(79)South West Regional Genetics Service, Bristol, United Kingdom.
(80)Department of Hematology and Oncology, University of Kansas Medical Center, 
Kansas City.
(81)Center for Hereditary Breast and Ovarian Cancer, Center for Integrated 
Oncology (CIO), and Center for Molecular Medicine Cologne (CMMC), Medical 
Faculty, University of Cologne and University Hospital Cologne, Cologne, 
Germany.
(82)Institute for Medical Informatics, Statistics and Epidemiology, University 
of Leipzig, Leipzig, Germany.
(83)Department of Gynaecology and Obstetrics, Division of Tumor Genetics, 
Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
(84)Department of Gynecology and Obstetrics, University Medical Center 
Schleswig-Holstein, Campus Kiel, Germany.
(85)Institute of Human Genetics, University Medical Center Schleswig-Holstein, 
Campus Kiel, Germany.
(86)Department of Gynaecology and Obstetrics, University Hospital Düsseldorf, 
Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
(87)Institute of Human Genetics, Department of Human Genetics, University 
Hospital Heidelberg, Heidelberg, Germany.
(88)Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, 
Germany.
(89)Institute of Cell and Molecular Pathology, Hannover Medical School, 
Hannover, Germany.
(90)Department of Gynaecology and Obstetrics, University Hospital Carl Gustav 
Carus, Technical University Dresden, Dresden, Germany.
(91)Institute of Human Genetics, Technical University Dresden, Dresden, Germany.
(92)Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin, 
Berlin, Germany.
(93)Centre of Familial Breast and Ovarian Cancer, Department of Medical 
Genetics, Institute of Human Genetics, University of Würzburg, Würzburg, 
Germany.
(94)Institute of Human Genetics, University of Regensburg, Regensburg, Germany.
(95)Institut Curie, Department of Tumour Biology, Paris, France98Institut Curie, 
INSERM U830, Paris, France99Université Paris Descartes, Sorbonne Paris Cité, 
France.
(96)Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices 
Civils de Lyon-Centre Léon Bérard, Lyon, France101INSERM U1052, CNRS UMR5286, 
Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
(97)INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en 
Cancérologie de Lyon, Lyon, France.
(98)Institut Curie, Department of Tumour Biology, Paris, France99Université 
Paris Descartes, Sorbonne Paris Cité, France.
(99)Institut Curie, Department of Tumour Biology, Paris, France.
(100)Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices 
Civils de Lyon-Centre Léon Bérard, Lyon, France.
(101)Université Lyon 1, CNRS UMR5558, Lyon, France103Unité de Prévention et 
d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France.
(102)Département Oncologie Génétique, Prévention et Dépistage, INSERM CIC-P9502, 
Institut Paoli-Calmettes/Université d'Aix-Marseille II, Marseille, France.
(103)Laboratoire d'Oncologie Moléculaire Humaine, Centre Oscar Lambret, Lille, 
France.
(104)Unité d'Oncogénétique, CLCC Paul Strauss, Strasbourg, France.
(105)Service de Génétique Biologique-Histologie-Biologie du Développement et de 
la Reproduction, Centre Hospitalier Universitaire de Besançon, Besançon, France.
(106)Service de Génétique, Centre Hospitalier Universitaire Bretonneau, Tours, 
France.
(107)Oncogénétique Clinique, Hôpital René Huguenin/Institut Curie, Saint-Cloud, 
France.
(108)Laboratoire d'Oncogénétique, Hôpital René Huguenin/Institut Curie, 
Saint-Cloud, France.
(109)Lombardi Comprehensive Cancer Center, Georgetown University, Washington, 
DC.
(110)Center for Medical Genetics, Ghent University, Ghent, Belgium.
(111)GOG Statistical and Data Center, Buffalo, New York.
(112)Evanston Hospital, Evanston, Illinois.
(113)Tufts University, Medford, Massachusetts.
(114)University of North Carolina, Chapel Hill.
(115)New York University, New York, New York.
(116)Ohio State, Good Samaritan Hospital, Cincinnati.
(117)Yale University School of Medicine, New Haven, Connecticut.
(118)Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, 
Spain.
(119)Department of Obstetrics and Gynecology, University of Helsinki and 
Helsinki University Central Hospital, Helsinki, Finland.
(120)Department of Clinical Genetics, Helsinki University Central Hospital, 
Helsinki, Finland.
(121)Department of Genetics, University Medical Center, Groningen University, 
Groningen, The Netherlands.
(122)Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The 
Netherlands.
(123)Department of Clinical Genetics, Family Cancer Clinic, Erasmus University 
Medical Center, Rotterdam, The Netherlands.
(124)Department of Medical Oncology, Family Cancer Clinic, Erasmus University 
Medical Center, Rotterdam, The Netherlands.
(125)Department of Clinical Genetics, VU University Medical Centre, Amsterdam, 
The Netherlands.
(126)Department of Human Genetics and Department of Clinical Genetics, Leiden 
University Medical Center, Leiden, The Netherlands.
(127)Department of Clinical Genetics and GROW, School for Oncology and 
Developmental Biology, MUMC, Maastricht, The Netherlands.
(128)Department of Human Genetics, Radboud University Nijmegen Medical Centre, 
Nijmegen, The Netherlands.
(129)Department of Medical Genetics, University Medical Center Utrecht, Utrecht, 
The Netherlands.
(130)Department of Clinical Genetics, Academic Medical Center, Amsterdam, The 
Netherlands.
(131)Department of Human Genetics and Department of Pathology, Leiden University 
Medical Center, Leiden, The Netherlands.
(132)Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong135Cancer 
Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong136Department of 
Surgery, University of Hong Kong, Hong Kong.
(133)Department of Molecular Genetics, National Institute of Oncology, Budapest, 
Hungary.
(134)Oncogenetics Laboratory, Vall d'Hebron Institute of Oncology (VHIO), 
Universitat Autonoma de Barcelona, Barcelona, Spain139University Hospital of 
Vall d'Hebron, Barcelona, Spain.
(135)Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan 
Institute of Oncology, Barcelona, Spain.
(136)Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI-Catalan 
Institute of Oncology, Girona, Spain.
(137)Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan 
Institute of Oncology, Barcelona, Spain.
(138)Department of Genetics and Pathology, Pomeranian Medical University, 
Szczecin, Poland.
(139)Department of Genetics and Pathology, Pomeranian Medical University, 
Szczecin, Poland144Postgraduate School of Molecular Medicine, Warsaw Medical 
University, Warsaw, Poland.
(140)Department of Surgical Gynecology and Gynecological Oncology of Adults and 
Adolescents, Pomeranian Medical University, Szczecin, Poland.
(141)Department of Pathology, Landspitali University Hospital, Reykjavík, 
Iceland147BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
(142)Canada Research Chair in Oncogenetics, Cancer Genomics Laboratory, Centre 
Hospitalier Universitaire de Québec Research Center, Quebec City, Quebec, 
Canada149Laval University, Quebec City, Quebec, Canada.
(143)Medical Genetics Division, Centre Hospitalier Universitaire de Québec, 
Quebec City, Quebec, Canada151Immunology and Molecular Oncology Unit, Veneto 
Institute of Oncology, IOV-IRCCS, Padua, Italy.
(144)Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, 
IOV-IRCCS, Padua, Italy.
(145)Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.
(146)Department of Genetics, Portuguese Oncology Institute, Porto, 
Portugal153Biomedical Sciences Institute (ICBAS), University of Porto, Portugal.
(147)Department of Surgery, Soonchunhyang University and Hospital, Seoul, Korea.
(148)Department of Preventive Medicine, Seoul National University College of 
Medicine and Cancer Research Institute, Seoul National University, Seoul, Korea.
(149)Department of Surgery, Daerim St Mary's Hospital, Seoul, Korea.
(150)Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, 
Minnesota159Department of Health Sciences Research, Mayo Clinic, Rochester, 
Minnesota.
(151)Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
(152)Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, 
Minnesota.
(153)Program in Cancer Genetics, Departments of Human Genetics and Oncology, 
McGill University, Montreal, Quebec, Canada161Department of Medical Genetics, 
University of Cambridge, Cambridge, United Kingdom.
(154)Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer 
Institute and MF MU, Brno, Czech Republic.
(155)Clinical Genetics Service, Cancer Biology and Genetics Program, Memorial 
Sloan-Kettering Cancer Center, New York, New York.
(156)Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New 
York, New York.
(157)Department of OB/GYN and Comprehensive Cancer Center, Medical University of 
Vienna, Vienna, Austria.
(158)Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, 
National Cancer Institute, National Institutes of Health, Rockville, Maryland.
(159)N. N. Petrov Institute of Oncology, St Petersburg, Russia.
(160)Divison of Human Cancer Genetics, Departments of Internal Medicine and 
Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer 
Center, Ohio State University, Columbus.
(161)Divison of Human Genetics, Department of Internal Medicine, Comprehensive 
Cancer Center, Ohio State University, Columbus.
(162)Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.
(163)Section of Molecular Diagnostics, Department of Clinical Biochemistry, 
Aalborg University Hospital, Aalborg, Denmark.
(164)Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, 
Denmark.
(165)Department of Clinical Genetics, Odense University Hospital, Odense C, 
Denmark.
(166)Section of Genetic Oncology, Department of Oncology, University of Pisa and 
University Hospital of Pisa, Pisa, Italy.
(167)Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang 
Jaya, Malaysia176Department of Surgery, Faculty of Medicine, University Malaya 
Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia.
(168)NorthShore University HealthSystem, Department of Medicine, Evanston, 
Illinois.
(169)Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and University 
of Toronto, Toronto, Ontario, Canada.