Promoters have diverse regulatory architectures and thus activate genes 
differently. For example, some have a TATA-box, many others do not. Even the 
ones with it can differ in its position relative to the transcription start site 
(TSS). No Promoter Left Behind (NPLB) is an efficient, organism-independent 
method for characterizing such diverse architectures directly from 
experimentally identified genome-wide TSSs, without relying on known promoter 
elements. As a test case, we show its application in identifying novel 
architectures in the fly genome.
AVAILABILITY AND IMPLEMENTATION: Web-server at http://nplb.ncl.res.in Standalone 
also at https://github.com/computationalBiology/NPLB/ (Mac OSX/Linux).
CONTACT: l.narlikar@ncl.res.in
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics 
online.