Sarcoidosis is still a mysterious disease since we don't know exactly what is 
the cause. Interestingly some patients get cured without any treatment. There is 
still a controversy about the indications of treatment in sarcoidosis. This 
article is an update on pharmacologic treatment in sarcoidosis. Corticosteroids 
are still the first-line treatment, but alternative therapy with anti-TNF 
agents, like pentoxifylline, thalidomide and anti-TNF monoclonal antibodies 
become more interesting, especially in refractory sarcoidosis.