The neoplastic proliferation of single clones of plasma cells causes synthesis 
of very large amount of monoclonal immunoglobulins consisting of only one type 
of heavy either the gamma, alpha, mu, delta or epsilon chain or only kappa or 
lambda light chains. Each monoclonal immunolobulin differs idiotypically from 
each other. These monoclonal immunoglobulins are also called paraproteins and 
are frequently associated with a broad heterogeneous group of plasma cell 
dyscrasias. Occasionally their presence is observed in a few benign conditions 
and in old age. In the present review a detailed account of different types of 
monoclonal gammapathies are described.