REPAIRtoire is the first comprehensive database resource for systems biology of 
DNA damage and repair. The database collects and organizes the following types 
of information: (i) DNA damage linked to environmental mutagenic and cytotoxic 
agents, (ii) pathways comprising individual processes and enzymatic reactions 
involved in the removal of damage, (iii) proteins participating in DNA repair 
and (iv) diseases correlated with mutations in genes encoding DNA repair 
proteins. REPAIRtoire provides also links to publications and external 
databases. REPAIRtoire contains information about eight main DNA damage 
checkpoint, repair and tolerance pathways: DNA damage signaling, direct reversal 
repair, base excision repair, nucleotide excision repair, mismatch repair, 
homologous recombination repair, nonhomologous end-joining and translesion 
synthesis. The pathway/protein dataset is currently limited to three model 
organisms: Escherichia coli, Saccharomyces cerevisiae and Homo sapiens. The DNA 
repair and tolerance pathways are represented as graphs and in tabular form with 
descriptions of each repair step and corresponding proteins, and individual 
entries are cross-referenced to supporting literature and primary databases. 
REPAIRtoire can be queried by the name of pathway, protein, enzymatic complex, 
damage and disease. In addition, a tool for drawing custom DNA-protein complexes 
is available online. REPAIRtoire is freely available and can be accessed at 
http://repairtoire.genesilico.pl/.