Mal de Debarquement Syndrome (MDS) is a rare, understudied, underdiagnosed, and 
self-limiting condition. Etiology and incidence are unknown. It is characterized 
by abnormal sensation of motion/balance reported after travel by air, land, and 
sea; being reexposed to motion/activity relieves it. Symptoms may last from 
minutes to years. Workup though required reveals no findings; it is a diagnosis 
of exclusion. While no efficacious treatment exists, amitriptyline and 
benzodiazepines as well as supportive therapy have proved to be useful. We have 
described a 40-year-old Caucasian female who presented for the evaluation of 
persistent rocking and swaying sensation after a ship cruise which lasted for 
one week. Patient was treated with benzodiazepines after extensive workup and is 
now stable. A high index of suspicion is required to make a diagnosis.