The drugs used to treat diabetes mellitus are diverse and include several 
classes. One class is sulfonylureas which primarily cause serum glucose 
reduction by stimulating the release of preformed insulin from the pancreatic 
islets. Gliclazide, a second generation sulfonylurea, is used to control 
glycemic levels in non-insulin-dependent diabetes mellitus. We report a 14 
year-old non-diabetic girl who developed hepatitis, hemiplegia and dysphasia 
after ingestion of an overdose of gliclazide (20 mg/kg/day) in a suicide 
attempt. Our purpose is to draw attention to the severity of gliclazide-induced 
neurological signs. To the best of our knowledge, gliclazide-induced hemiplegia 
and dysphasia have not been previously reported in the literature.