A wide spectrum of skin toxicities has been described in patients receiving 
epidermal growth factor receptor (EGFR), inhibitors, including papulopustular 
rash, xerosis and fissures, pruritus, mucositis, paronychia, and hair 
changes.Trichomegaly of the eyelashes is a rare adverse effect of EGFR inhibitor 
therapy and is characterized by a paradoxical overgrowth of eyelashes. We 
present 3 cases of trichomegaly occurred during EGFR inhibitor therapy.