Fungicidal effects of histatin-5 against 26 oral isolates belonging to 5 
non-albicans Candida species were examined. Fifty microM of histatin-5 killed 
more than 95% of Candida tropicalis and Candida guilliermondii isolates and more 
than 90% of Candida parapsilosis and Candida krusei. However, Candida glabrata 
was less sensitive to the peptide (mean 62.9%). Our results, taken together, 
demonstrated that histatin-5 possessed the fungicidal activity against Candida 
species other than C. glabrata.