3D Printing promises to produce complex biomedical devices according to computer 
design using patient-specific anatomical data. Since its initial use as 
pre-surgical visualization models and tooling molds, 3D Printing has slowly 
evolved to create one-of-a-kind devices, implants, scaffolds for tissue 
engineering, diagnostic platforms, and drug delivery systems. Fueled by the 
recent explosion in public interest and access to affordable printers, there is 
renewed interest to combine stem cells with custom 3D scaffolds for personalized 
regenerative medicine. Before 3D Printing can be used routinely for the 
regeneration of complex tissues (e.g. bone, cartilage, muscles, vessels, nerves 
in the craniomaxillofacial complex), and complex organs with intricate 3D 
microarchitecture (e.g. liver, lymphoid organs), several technological 
limitations must be addressed. In this review, the major materials and 
technology advances within the last five years for each of the common 3D 
Printing technologies (Three Dimensional Printing, Fused Deposition Modeling, 
Selective Laser Sintering, Stereolithography, and 3D 
Plotting/Direct-Write/Bioprinting) are described. Examples are highlighted to 
illustrate progress of each technology in tissue engineering, and key 
limitations are identified to motivate future research and advance this 
fascinating field of advanced manufacturing.