A best evidence topic in surgery was written according to a structured protocol. 
The question addressed whether LINX™ Reflux management system is an efficacious 
treatment for patients with symptoms of gastro-oesophageal reflux disease (GORD) 
not controlled by proton pump inhibitors (PPI). Forty-eight LINX-related papers 
were identified using the reported search, of which three represented the best 
evidence to answer the clinical question. The authors, journal, date and country 
of publication, patient group, study type, relevant outcomes and results of 
these papers are tabulated. All three studies were prospective case studies. 
They demonstrated that LINX is an efficacious treatment for GORD patients with 
good short and medium term outcomes and an acceptable safety profile. Further 
studies are required to determine its long term outcomes and its relative 
efficacy as compared to other established treatments.