Diamond Blackfan Anemia (DBA) is a rare hypoplastic anemia that presents in 
infancy with macrocytic anemia and reticulocytopenia. It is a ribosomopathy with 
autosomal dominant inheritance. In our series of 10 patients with DBA, 
congenital malformations were observed in 50% of the cases. Age at symptom onset 
ranged from 0-12 months. Age at diagnosis ranged from 4 months to 96 months. 
Male: female ratio was 9:1. Response to prednisolone was observed in 4 out of 
the 10 patients (either during initial treatment or during re-challenge). 
Response to cyclosporine was found to be poor. Bone marrow transplantation was 
successful in attaining remission in one patient. Malignancies were not reported 
in any patient possibly due to a short follow up period.