Methyltranscriptome is an exciting new area that studies the mechanisms and 
functions of methylation in transcripts. The MethylTranscriptome DataBase 
(MeT-DB, http://compgenomics.utsa.edu/methylation/) is the first comprehensive 
resource for N6-methyladenosine (m(6)A) in mammalian transcriptome. It includes 
a database that records publicaly available data sets from methylated RNA 
immunoprecipitation sequencing (MeRIP-Seq), a recently developed technology for 
interrogating m(6)A methyltranscriptome. MeT-DB includes ∼ 300 k m(6)A 
methylation sites in 74 MeRIP-Seq samples from 22 different experimental 
conditions predicted by exomePeak and MACS2 algorithms. To explore this rich 
information, MeT-DB also provides a genome browser to query and visualize 
context-specific m(6)A methylation under different conditions. MeT-DB also 
includes the binding site data of microRNA, splicing factor and RNA binding 
proteins in the browser window for comparison with m(6)A sites and for exploring 
the potential functions of m(6)A. Analysis of differential m(6)A methylation and 
the related differential gene expression under two conditions is also available 
in the browser. A global perspective of the genome-wide distribution of m(6)A 
methylation in all the data is provided in circular ideograms, which also act as 
a navigation portal. The query results and the entire data set can be exported 
to assist publication and additional analysis.