Tularemia is a zoonosis caused by Francisella tularensis that can be transmitted 
by several ways to human being and cause different clinical manifestations. We 
report three clinical cases of tularemia with ulceroglandular presentation in 
young males acquired during outdoor activities in Southern Belgium. Confirmation 
of the diagnosis was established by serology. Only three cases of tularemia have 
been reported in Belgium between 1950 and 2012 by the National Reference 
Laboratory CODA-CERVA (Ref Lab CODA-CERVA) but re-emergence of tularemia is 
established in several European countries and F. tularensis is also well known 
to be present in animal reservoirs and vectors in Belgium. The diagnosis of 
tularemia has to be considered in case of suggestive clinical presentation 
associated with epidemiological risk factors.