Therapeutic hypothermia is a recognized treatment for term infants with 
hypoxic-ischemic encephalopathy (HIE) in reducing rate of death or 
neurodevelopmental disabilities. Little is known about applications of this 
treatment to preterm newborns. Studies in animal experimental models 
demonstrated the efficacy of hypothermia in preterm fetuses but clinical 
application to newborn infants are limited to restricted cases, as severe 
necrotizing enterocolitis (NEC). We present a case of therapeutic whole body 
cooling in a baby at 34 weeks and 6 days of gestational age with HIE.