Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a 
rare immunodeficiency disorder. We report three patients with WHIM syndrome who 
are affected by Tetralogy of Fallot (TOF). This observation suggests a possible 
increased risk of TOF in WHIM syndrome and that birth presentation of TOF and 
neutropenia should lead to suspect WHIM syndrome.