The literature in most European languages was consulted for guidelines regarding 
the drug treatment of psychiatrically disturbed pregnant or lactating women. The 
available information allows only a few conclusions. Lithium exposure during the 
first trimester seems to increase the risk of congenital heart disease, 
especially Ebstein's anomaly. As there is still insufficient evidence to prove 
the safeness of other psychoactive drugs for the fetus, caution seems warranted 
here too. A causal link between pharmacotherapy of the mother-to-be and 
malformation of the baby is difficult to prove. But toxic and withdrawal 
symptoms in infants born to women treated regularly until shortly before 
confinement are well documented for most psychoactive drugs.