Morton's neuroma is the fibrous enlargement of the interdigital nerve branches, 
usually in the second and third interspace between the metatarsal heads where 
the lateral and medial plantar nerves often join. Specific symptoms are dull or 
sharp pain, numbness and/or tingling in the third and fourth digits, burning 
sensation, cramping, and a feeling of "walking on a stone" around the metatarsal 
heads. Numerous clinical tests for Morton's neuroma have been described, such as 
thumb index finger squeeze, and Mulder's click and foot squeeze tests. 
Ultrasound and magnetic resonance imaging can be used for confirmation, 
especially for differential diagnosis, exact localization, and number of 
neuromas. Further, performing dynamic imaging during the aforementioned tests is 
paramount and can readily be carried out with ultrasound. The treatment mainly 
comprises footwear modifications, radiofrequency ablation, physical therapy, 
local (corticosteroid and anesthetic) injections into the affected webspace, and 
surgery. Again the use of real-time ultrasound guidance during such 
interventions is noteworthy.