Author information:
(1)Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
(2)Inflammatory Bowel Disease Research Group, Addenbrooke's Hospital, Cambridge, 
UK.
(3)Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne.
(4)Division of Genetics and Rheumatology, Brigham and Women's Hospital, Harvard 
Medical School, Boston, MA, USA.
(5)Program in Medical and Population Genetics, Broad Institute of Harvard and 
MIT, Cambridge, MA, USA.
(6)Precision Medicine Exeter, University of Exeter, Exeter, UK.
(7)IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK.
(8)Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, 
UK.
(9)Christ Church, University of Oxford, St Aldates, UK.
(10)Gastrointestinal Unit, Wester General Hospital University of Edinburgh, 
Edinburgh, UK.
(11)Department of Gastroenterology, Torbay Hospital, Torbay, Devon, UK.
(12)Department of Child Life and Health, University of Edinburgh, Edinburgh, UK.
(13)Department of Paediatric Gastroenterology and Nutrition, Royal Hospital for 
Sick Children,Edinburgh, UK.
(14)Department of Medicine, Ninewells Hospital and Medical School, Dundee, UK.
(15)Guy's & St Thomas' NHS Foundation Trust, St Thomas' Hospital, Department of 
Gastroenterology, London, UK.
(16)Translational Gastroenterology Unit, John Radcliffe Hospital, University of 
Oxford, Oxford OX3 9DS, UK.
(17)Human Immunology Unit, Weatherall Institute of Molecular Medicine, 
University of Oxford, Oxford OX3 9DS, UK.
(18)Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, 
Edinburgh, UK.
(19)Child Life and Health, University of Edinburgh, Edinburgh, Scotland, UK.
(20)Gastroenterology & General Medicine, Norfolk and Norwich University 
Hospital, Norwich, UK.
(21)Department of Medicine, St Mark's Hospital, Harrow, Middlesex, UK.
(22)Department of Medical and Molecular Genetics, Faculty of Life Science and 
Medicine, King's College London, Guy's Hospital, London, UK.
(23)Sydney Brenner Institute for Molecular Bioscience, Faculty of Health 
Sciences, University of Witwatersrand, South Africa.
(24)Genetic Medicine, Manchester Academic Health Science Centre, Manchester, UK.
(25)The Manchester Centre for Genomic Medicine, University of Manchester, 
Manchester, UK.
(26)Translational Gastroenterology Unit and the Department of Paediatrics, 
University of Oxford, Oxford, United Kingdom.
(27)Nottingham Digestive Diseases Centre, Queens Medical Centre, Nottingham, UK.
(28)Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK.
(#)Contributed equally