Jitteriness and tremors in the newborn period typically precipitate an 
extensive, invasive, and expensive search for the etiology. Vitamin D deficiency 
has not been historically included in the differential of tremors. We report a 
shivering, jittery newborn who was subjected to a battery of testing, with the 
only biochemical abnormality being vitamin D deficiency. A second case had chin 
tremors and vitamin D deficiency. Review of our patients suggests that shudders, 
shivers, jitteriness, or tremors may be the earliest sign of vitamin D 
deficiency in the newborn. Neonates who present with these signs should be 
investigated for vitamin D deficiency.