Thromboembolism in pregnancy and the puerperium and inherited or acquired 
thrombophilia are associated. Thrombophilia can be revealed by pregnancy. 
Thrombotic risk during pregnancy and the puerperium is higher in asymptomatic 
women with than without thrombophilia. Antithrombin deficiency, combined 
deficiencies and homozygous or double-heterozygotes factor V Leiden and factor 
II G 20210 A mutations are associated with a higher thrombotic risk than 
heterozygote mutations or protein S and C deficiencies, whereas 
hyperhomocysteinemia does not appear as a risk factor for maternal 
thromboembolic disease. Antiphospholipid syndrome with lupus anticoagulant is 
strongly associated with thrombotic risk in pregnancy and the puerperium. 
Further studies are required to assess the thrombotic risk in women with 
preeclampsia as well as early or late recurrent pregnancy loss.