The pathogenesis of Coronavirus disease 2019 is still obscure and the need for 
exploration of possible mechanisms to suggest drugs based on knowledge should 
never be delayed. In this manuscript, we present a novel theory to explain the 
pathogenesis of COVID-19; lymphocyte distraction theory upon which the author 
has used, in a preprinted protocol, non-steroidal anti-inflammatory drugs 
(NSAIDs); diclofenac potassium, ibuprofen and ketoprofen, successfully to treat 
COVID-19 patients. Furthermore, we agree with a recommendation that 
glucocorticoids should not be used routinely for COVID-19 patients and suggested 
to be beneficial only for patients with late acute respiratory distress 
syndrome. A clinical proof of ibuprofen safety in COVID-19 has been published by 
other researchers and we suggest that early administration of NSAIDs, including 
ibuprofen, in COVID-19 is not only safe but it might also prevent COVID-19 
complications and this manuscript explains some of the suggested associated 
protective mechanisms.