PURPOSE: To evaluate the ability of new Swept source (SS) optical coherence 
tomography (OCT) technology to detect changes in retinal and choroidal thickness 
in patients with Parkinson's disease (PD).
DESIGN: Observational case-control cross sectional study, developed from January 
to May 2016.
METHODS: In total, 50 eyes from 50 patients diagnosed with PD and 54 eyes of 54 
healthy controls underwent retinal and choroidal assessment using SS DRI Triton 
OCT (Topcon), using the 3D Wide protocol. Total macular thickness and 
peripapillary data (retinal, ganglion cell layer [GCL+, GCL++] and retinal nerve 
fiber layer [RNFL] thickness) were analyzed. Macular and peripapillary choroidal 
thickness was evaluated (Figure 1).
RESULTS: Significant peripapillary retinal thinning was observed in PD patients 
in total average (p = 0.017), in the nasal (p = 0.038) and temporal (p = 0.004) 
quadrants and in superotemporal (p = 0.004), nasal (p = 0.039), inferotemporal 
(p = 0.019), and temporal (p = 0.003) sectors. RNFL and GCL ++ thickness showed 
a significant reduction in the inferotemporal sector (p = 0.026 and 0.009, 
respectively). No differences were observed in macular retinal thickness between 
controls and patients. Choroidal thickness was found to have increased in all 
sectors in PD patients compared with controls, both in the macular (inner nasal, 
p = 0.015; inner inferior, p = 0.030; outer nasal, p = 0.012; outer inferior, 
p = 0.049) and the peripapillary area (total thickness, p = 0.011; nasal, 
p = 0.025; inferior, p = 0.007; temporal, p = 0.003; inferotemporal, p = 0.003; 
inferonasal, p = 0.016) Conclusion: New SS technology for OCT devices detects 
retinal thinning in PD patients, providing increased depth analysis of the 
choroid in these patients. The choroid in PD may present increased thickness 
compared to healthy individuals; however, more studies and histological analysis 
are needed to corroborate our findings.