The blood serum TSH and PRL levels were studied in 12 ALS patients after TRH 
stimulation. The TSH test was repeated after 4-weeks TRH treatment. The results 
were compared with the data obtained in the control group. It was shown that 
after TRH stimulation the TSH responses did not reveal greater abnormalities, 
but PRL responses were significantly diminished. The results could confirm our 
previous observations concerning the dysregulation of dopamine metabolism in ALS 
patients.