Conflict of interest statement: Declaration of Interests P.S. has served as an 
uncompensated consultant to Roche-Genentech. S.L. receives research funding to 
her institution from Novartis, Bristol Meyers Squibb, Merck, Roche-Genentech, 
Puma Biotechnology, Pfizer, Eli Lilly, and Seattle Genetics. She has acted as 
consultant (not compensated) to Seattle Genetics, Pfizer, Novartis, BMS, Merck, 
AstraZeneca, and Roche-Genentech. She has acted as consultant (paid to her 
institution) to Aduro Biotech, Novartis, and G1 Therapeutics.