The segregation of brown (type IV) oculocutaneous albinism was analyzed in 18 
Nigerian families. Analysis using the POINTER program showed that this type of 
oculocutaneous albinism was inherited in an autosomal recessive pattern, with an 
estimated gene frequency of 0.025 +/- 0.007 in this population. The enzyme 
defect responsible for brown oculocutaneous albinism is unknown.