We present RADAR--a rigorously annotated database of A-to-I RNA editing 
(available at http://RNAedit.com). The identification of A-to-I RNA editing 
sites has been dramatically accelerated in the past few years by high-throughput 
RNA sequencing studies. RADAR includes a comprehensive collection of A-to-I RNA 
editing sites identified in humans (Homo sapiens), mice (Mus musculus) and flies 
(Drosophila melanogaster), together with extensive manually curated annotations 
for each editing site. RADAR also includes an expandable listing of 
tissue-specific editing levels for each editing site, which will facilitate the 
assignment of biological functions to specific editing sites.