Left ventricular non-compaction cardiomyopathy is a rare congenital 
cardiomyopathy that affects both children and adults. Since the clinical 
manifestations are not sufficient to establish diagnosis, echocardiography is 
the diagnostic tool that makes it possible to document ventricular 
non-compaction and establish prognostic factors. We report a 47-year-old woman 
with a history of dilated cardiomyopathy with unknown etiology. Echocardiography 
showed mild left ventricular enlargement with severe systolic dysfunction (EF = 
20-25%). According to cardiac magnetic resonance imaging findings non-compaction 
left ventricle with hypertrophic cardiomyopathy was considered, and right 
ventricular septal biopsy was recommended. Right ventricular endomyocardial 
biopsy showed moderate hypertrophy of cardiac myocytes with foci of myocytolysis 
and moderate interstitial fibrosis. No evidence of infiltrative deposition was 
seen.