Author information:
(1)Drug Metabolism and Pharmacokinetics, Research and Early Development, 
Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, 
Gothenburg, Sweden.
(2)Fraunhofer-Chalmers Centre, Chalmers Science Park, Gothenburg, Sweden.
(3)Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology 
and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
(4)Department of Biomedical Engineering, University of Virginia, 
Charlottesville, Virginia, USA.
(5)Bioscience Cardiovascular, Research and Early Development, Cardiovascular, 
Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
(6)Integrative Systems Biology, Department of Biomedical Engineering, Linköping 
University, Linköping, Sweden.
(7)Research and Early Development, Cardiovascular, Renal and Metabolism, 
BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
(8)Integrated Cardiometabolic Center, Karolinska Institute, Huddinge, Sweden.
(9)Department of Cell and Molecular Biology and Medicine, Karolinska Institute, 
Stockholm, Sweden.