The University of California Santa Cruz (UCSC) Genome Browser is a popular 
Web-based tool for quickly displaying a requested portion of a genome at any 
scale, accompanied by a series of aligned annotation "tracks." The annotations 
generated by the UCSC Genome Bioinformatics Group and external collaborators 
include gene predictions, mRNA and expressed sequence tag alignments, simple 
nucleotide polymorphisms, expression and regulatory data, phenotype and 
variation data, and pairwise and multiple-species comparative genomics data. All 
information relevant to a region is presented in one window, facilitating 
biological analysis and interpretation. The database tables underlying the 
Genome Browser tracks can be viewed, downloaded, and manipulated using another 
Web-based application, the UCSC Table Browser. Users can upload personal 
datasets in a wide variety of formats as custom annotation tracks in both 
browsers for research or educational purposes. This unit describes how to use 
the Genome Browser and Table Browser for genome analysis, download the 
underlying database tables, and create and display custom annotation tracks.