Pseudotumor cerebri or benign intracranial hypertension is a syndrome of raised 
intracranial pressure without obvious explanation. Most patients are obese women 
at childbearing age. Symptoms and signs usually include headache, nausea, 
vomiting, edema of the papilla, visual obscurations and rarely palsy of the 
nervus abducens. The prognosis is generally good, but progressive visual loss 
and eventual blindness are major risks. We report the case of a 21-year-old 
non-obese young woman who developed pseudotumor cerebri while taking minocycline 
for acne therapy. Identical symptoms occurred upon inadvert rechallenge with 
minocycline for the second time.