Infantile hemangiomas (IH) are common benign tumors in infancy, affecting 5-10% 
of all infants and they can still cause disfigurement and serious complications 
depending on their location and size, which can be associated with ulcerations 
and haemorrhage. Since 2008, propranolol has become the first choice of therapy 
for complicated IH, compared to conventional approach with systemic 
corticosteroid therapy as first-line treatment and then interferon or 
vincristine as second- or third-line therapeutic agents. We report three cases 
of hemangioma, successfully treated with propranolol. Oral propranolol was given 
for a period of 6 months with monthly follow up. All cases showed dramatic 
response without any relapse after stopping the treatment. Propranolol is novel 
and safe medication for treatment of infantile hemangioma.