Controversy remains regarding the best treatment for primary gastric lymphoma 
(PGL). Recent developments in diagnosis and chemotherapy have changed strategies 
for this disease. Fourteen patients with primary gastric non-Hodgkin's lymphoma 
underwent surgery. Before surgery 9/14 patients underwent Helicobacter pylori 
eradication, and 4/14 were treated with chemotherapy. In two patients 
chemotherapy was not possible because of risk of perforation recurred. Total 
gastrectomy with N2 lymphadenectomy, splenectomy, biopsy of mesenteric lymph 
nodes, and hepatic biopsy were done. Then patients underwent post-operative 
chemotherapy. Involved-field radiation therapy was made in four patients. The 
overall survival was 64.2 percent. Surgery was the treatment of choice in cases 
of gastric lymphoma non-responsive to medical therapy and to control 
complications or when gastroscopy did not supply correct diagnosis.