BACKGROUND/AIMS: To validate the AIMS65 score for predicting mortality of 
patients with nonvariceal upper gastrointestinal bleeding and to evaluate the 
effectiveness of urgent (<8 hours) endoscopic procedures in patients with high 
AIMS65 scores.
METHODS: This was a 5-year single-center, retrospective study. Nonvariceal, 
upper gastrointestinal bleeding was assessed by using the AIM65 and Rockall 
scores. Scores for mortality were assessed by calculating the area under the 
receiver-operating characteristic curve (AUROC). Patients with high AIMS65 
scores (≥2) were allocated to either the urgent or non-urgent endoscopic 
procedure group. In-hospital mortality, success of endoscopic procedure, 
recurrence of bleeding, admission period, and dose of transfusion were compared 
between groups.
RESULTS: A total of 634 patients were analyzed. The AIMS65 score successfully 
predicted mortality (AUROC=0.943; 95% confidence interval [CI], 0.876 to 0.99) 
and was superior to the Rockall score (AUROC=0.856; 95% CI, 0.743 to 0.969) in 
predicting mortality. The group with high AIMS65 score included 200 patients. 
The urgent endoscopic procedure group had reduced hospitalization periods 
(p<0.05).
CONCLUSIONS: AIMS65 score may be useful in predicting mortality in patients with 
nonvariceal upper gastrointestinal bleeding. Urgent endoscopic procedures in 
patients with high scores may be related to reduced hospitalization periods.