Amniotic band syndrome (ABS) is a rare congenital disease with variable 
manifestations ranging from simple constriction rings at the extremities to 
major defects such as exencephaly. Here we report the case of a female baby born 
full term (39 weeks) from a 35-year-old primiparous mother by cesarean section. 
In addition to the constriction rings at the extremities (fingers), the newborn 
presented facial malformations and a cranial anomaly suggestive of exencephaly. 
Supportive treatment was chosen because of the poor prognosis, and the child 
died 5 months later. Depending on the anomaly associated with ABS and its 
complexity, as in our case, genetic studies should be performed whenever 
possible, and the parents should be informed about the possibility of 
recurrences and incompatibility with life.