Pediatric experience with gabapentin (GBP), a new antiepileptic drug (AED), is 
limited. We described 3 learning disabled children, 1 aged 7 and 2 aged 10 
years, with intractable partial seizures who developed severe behavioral 
problems while receiving modest doses of GBP. The children became hyperactive 
and had explosive outburst consisting of aggressive and oppositional behavior. 
The behavioral problems were sufficiently severe to require discontinuation of 
GBP despite moderately improved seizure control.