Local immunotherapy with bacillus Calmette-Guerin (BCG) is an effective and 
frequently used treatment for superficial bladder cancer. Serious side effects 
are infrequent but can affect every organ system. We describe a 53 year- old man 
with a disseminated bacillus Calmette-Guerin (BCG) infection after intravescical 
instillation for bladder carcinoma. Recent literature is reviewed for this rare 
complication.