Neonatal lupus erythematosus (NLE) is an uncommon condition usually associated 
with maternal anti-Ro autoantibodies. The cutaneous lesions of NLE are usually 
transient, disappearing about six months after birth, but telangiectasia is a 
rare complication of NLE which persists. Telangiectasias are small focal red 
macules and papules created by abnormally prominent capillaries, venules, and 
arterioles and are a characteristic marker of connective tissue diseases. We 
report the case of an infant diagnosed with NLE presenting typical annular 
lesions, positive ANA and positive anti-Ro antibodies. By five months of age, 
both ANA and anti-Ro antibodies were negative and the annular cutaneous lesions 
had gradually faded, but small scattered focal red macules appeared on the face, 
especially in the peri-orbital area and scalp. The cutaneous lupus disappeared 
but the telangiectasia persisted. We would like to suggest that the diagnosis of 
NLE should be considered when cutaneous telangiectasias are observed in infants.