Thyroid hormone has various effects on the cardiovascular system and its effects 
on cardiac contractility, heart rhythm and vascular function has long been 
recognized. However, new evidence is emerged on the importance of thyroid 
hormone in the response of the myocardium to ischaemic stress and cardiac 
remodelling following myocardial infarction. Based on this new information, this 
review highlights the role of thyroid hormone in myocardial ischaemia and 
cardiac remodelling, the possible underlying mechanisms and the potential 
therapeutic implications. Thyroid hormone or analogs may prove new therapeutic 
agents for treating ischaemic heart disease.