A new study identifies homozygous missense mutations in SGOL1, which encodes a 
component of the cohesin complex, in a newly described disorder termed Chronic 
Atrial and Intestinal Dysrhythmia (CAID) syndrome. These findings implicate 
cohesin in the regulation of intrinsic cardiac and intestinal rhythm and further 
expand the growing group of disorders termed the cohesinopathies.