Mutations in the gene SLITRK1 (Slit and Trk-like 1) have been reported in 
patients with Tourette's disorder (TD). We sequenced the entire SLITRK1 gene 
including the coding region the 5' and 3' untranslated region in 92 Austrian 
patients with TD. No nucleotide changes within the protein-coding region were 
identified. One patient was found to carry a variant within the 3' untranslated 
region (3383g>a), which was absent in 192 control individuals and which 
segregated in two additional family members with tic symptoms. In conclusion, 
our results provide no evidence for SLITRK1 playing a major role in TD.