After a young woman had scarlet fever associated with group C beta-hemolytic 
streptococcal pharyngitis, we reviewed all cases of pharyngitis treated at a 
student health clinic during that semester. From 541 cases of pharyngitis, 34 
cultures yielded group C Streptococcus. The patients who harbored group C 
organisms were similar to the patients with group A streptococcal pharyngitis in 
the presence of fever, exudate, and cervical adenopathy. The severity of 
symptoms and the demonstration of scarlet fever developing from infection with 
this organism supports antibiotic treatment of patients with group C 
streptococcal pharyngitis.