With an increasing number of therapeutic drugs, the list of drugs that is 
responsible for severe pulmonary disease also grows. Many drugs have been 
associated with pulmonary complications of various types, including interstitial 
inflammation and fibrosis, bronchospasm, pulmonary edema, and pleural effusions. 
Drug-induced interstitial lung disease (DILD) can be caused by chemotherapeutic 
agents, antibiotics, antiarrhythmic drugs, and immunosuppressive agents. There 
are no distinct physiologic, radiographic or pathologic patterns of DILD, and 
the diagnosis is usually made when a patient with interstitial lung disease 
(ILD) is exposed to a medication known to result in lung disease. Other causes 
of ILD must be excluded. Treatment is avoidance of further exposure and systemic 
corticosteroids in patients with progressive or disabling disease.