The Ehlers-Danlos syndrome (EDS), inherited disorder of connective tissue, 
frequently leads to impairment of various functional areas, including 
employment. In 35 subjects with classic type EDS, 14 hypermobile, 3 vascular was 
administered 7 visual analogical scales (pain, stiffness, activities of daily 
living, instrumental activities of daily living, work, social relations). An 
impairment of particular significance in total score and in individual areas 
emerges is in the hypermobile group, followed by classic, less for the 
vasculature. Overall there is a significant alteration of the quality of life 
that deserves proper evaluation to facilitate the definition of fitness and the 
improvement of job insertion in patients with EDS.