Therapeutical action of mexidol as compared to piracetam was evaluated in groups 
of patients with tick borne encephalitis in the acute period of disease. Mexidol 
was administered as add-on to antiviral treatment in 72 patients while 89 
patients received piracetam. The drugs were introduced intravenously during the 
first 10 days and then were given as tablets during 2 months. Based on these 
results, we can recommend the inclusion of mexidol in the pathogenetic treatment 
(fever symptoms) of tick born encephalitis. The use of mexidol as compared to 
piracetam led to more pronounced positive changes, higher percentage of 
favorable outcomes and lower frequency of residual signs.