Author information:
(1)Clinical Pharmacology, William Harvey Research Institute, School of Medicine 
and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.
(2)European Molecular Biology Laboratory, European Bioinformatics Institute 
(EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
(3)The Jackson Laboratory, Bar Harbor, ME, 4609, USA.
(4)Departments of Molecular Physiology and Biophysics, Baylor College of 
Medicine, Houston, TX, 77030, USA.
(5)Departments of Molecular and Human Genetics, Baylor College of Medicine, 
Houston, TX, 77030, USA.
(6)Department of Genetics, Perelman School of Medicine, University of 
Pennsylvania, Philadelphia, PA, 19104, USA.
(7)The Centre for Phenogenomics, The Hospital for Sick Children, Toronto, ON, 
M5T 3H7, Canada.
(8)The Centre for Phenogenomics, Lunenfeld-Tanenbaum Research Institute, Mount 
Sinai Hospital, Toronto, ON, M5T 3H7, Canada.
(9)Medical Research Council Harwell Institute (Mammalian Genetics Unit and Mary 
Lyon Centre), Harwell, Oxfordshire, OX11 0RD, UK.
(10)German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum 
München, German Research Center for Environmental Health, 85764, Neuherberg, 
Germany.
(11)Université de Strasbourg, CNRS, INSERM, Institut Clinique de la Souris, 
PHENOMIN-ICS, 67404, Illkirch, France.
(12)Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech 
Academy of Sciences, Vestec, 252 50, Prague, Czech Republic.
(13)Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
(14)Institute of Developmental Genetics, Helmholtz Zentrum München, German 
Research Center for Environmental Health GmbH, 85764, Neuherberg, Germany.
(15)Department of Developmental Genetics, Center of Life and Food Sciences 
Weihenstephan, Technische Universität München, 85764, Neuherberg, Germany.
(16)Deutsches Institut für Neurodegenerative Erkrankungen (DZNE) Site Munich, 
Munich Cluster for Systems Neurology (SyNergy), Adolf-Butenandt-Institut, 
Ludwig-Maximilians-Universität München, 80336, Munich, Germany.
(17)Monterotondo Mouse Clinic, Italian National Research Council (CNR), 
Institute of Cell Biology and Neurobiology, 00015, Monterotondo Scalo, Italy.
(18)Translational Medicine, The Hospital for Sick Children, Toronto, ON, M5T 
3H7, Canada.
(19)Université de Strasbourg, CNRS, INSERM, Institut de Génétique, Biologie 
Moléculaire et Cellulaire, Institut Clinique de la Souris, IGBMC, PHENOMIN-ICS, 
67404, Illkirch, France.
(20)Department of Experimental Genetics, Center of Life and Food Sciences 
Weihenstephan, Technische Universität München, 85354, Freising-Weihenstephan, 
Germany.
(21)German Center for Diabetes Research (DZD), 85764, Neuherberg, Germany.
(22)Mouse Biology Program, University of California, Davis, CA, 95618, USA.
(23)Clinical Pharmacology, William Harvey Research Institute, School of Medicine 
and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK. 
d.smedley@qmul.ac.uk.
(#)Contributed equally