Celiac disease is an autoimmune disorder triggered by ingestion of 
gluten-containing foods. Epidemiologic studies dating from the 1950s established 
its association with gastrointestinal malignancies, particularly small bowel 
lymphoma. Corrao et al. recently demonstrated that patients with celiac disease 
are at increased risk of mortality. Further, this risk is directly related to 
compliance with a gluten-free diet. Continued research is needed regarding the 
development of malignant complications related to celiac disease.