Translocations involving acrocentric chromosomes are frequent in chromosomal 
male infertility. Robertsonian translocations are usually concerned whereas 
reciprocal translocations between acrocentric chromosomes are rarely 
encountered. The first reciprocal translocation involving the long arms of the 
two acrocentric chromosomes 13 and 14 [46,XY,t(13,14)(q33,q22)] is presented in 
this paper. The patient presents a severe oligoasthenospermia; testicular 
histology shows an important impairment of spermatogenesis. The quadrivalent is 
present in all the pachytene nuclei analyzed. A straight contact between the sex 
vesicle and the quadrivalent was found in 40.9% of the nuclei. A frequent 
asynapsis is localized at the breakpoint region (33.8%). The XY-autosome 
association was obtained by the central asynapsis and/or by the terminal 
chromomeres of the acrocentric chromosomes involved in the translocation.