The coincidence of aortic valve stenosis and cryptogenic gastrointestinal 
bleeding usually from angiodysplasia of the cecum and ascending colon has been 
called Heyde syndrome. The pathophysiologic link between both remains unclear 
and may be due to subtle changes in plasmatic coagulation. There are some 
statistic and numerous casuistic reports, and recently the existence of the 
syndrome has been questioned. We describe two cases of aortic valve stenosis and 
cryogenic gastrointestinal bleeding in which bleeding subsided after replacement 
with a bioprosthesis. We give an overview of the current literature.