In the last years, a considerable number of studies have been performed on the 
relationship between infection from Helicobacter Pylori and atherosclerotic 
diseases, like stroke and ischemic heart disease. In particular, some infections 
could have a role on the genesis and development of damage to the vascular wall 
and of atheromatous plaque. It has been suggested that HP could influence the 
development of IHD through different pathways, such as endothelial cells 
colonization, changes in the lipid profiles, increased coagulation and platelet 
aggregation levels, induction of molecular mimicry mechanisms and the promotion 
of a low-grade systemic inflammation. Based on this hypothesis, it has been 
performed a considerable number of studies in order to investigate the role of 
HP in the development and pathogenesis of CAD. Most of this trials gave 
conflicting results, some denying the presence of a possible relationship 
between HP infection and increased risk of CAD. Despite of that, results from 
these studies have raised new interesting perspectives on coronary heart 
disease, especially regarding the possibility of modifying the clinical history 
of the disease through eradication of these microorganisms. The results are 
contradictory and require further investigation.