Jaundice is a yellowish pigmentation of skin and mucous membranes caused by 
hyperbilirubinemia, which itself has various causes. Jaundice related to 
malignant tumors is classified as obstructive jaundice. This disease proceeds 
from biliary tract obstruction and liver failure by progression of intrahepatic 
tumors, including metastases from other malignancies. Biliary tract cancer, 
pancreatic head cancer, or lymph nodes metastases from other sites of cancer are 
mainly responsible for the obstruction of the bile duct. In patients with 
obstructive jaundice, biliary drainage is often required in order to give 
treatments such as chemotherapy. In patients with biliary drainage, various 
complications arise, such as cholangitis due to obstruction ofa biliary stent, 
and bleeding from the ulcer due to a dislodged stent to the duodenum. It is 
crucial to manage those complications as oncologic emergencies. Jaundice of 
liver failure due to hepatic metastases is often observed in patients with 
gastrointestinal malignancies such as gastric cancer or colorectal cancer. 
Although chemotherapy is the usual application for those patients, useful 
anti-cancer agents are limited. It is crucial to diagnose and decide the best 
treatments as soon as possible for patients with very advanced hepatic 
metastases.