AIM: Charcot neuroarthropathy is a very rare form of diabetic foot syndrome 
occurring among others in patients with diabetes mellitus. Charcot 
neuroarthropathy leads to bone tissue destruction and may result in foot 
amputation. The aim of the study was to identify risk factors of Charcot 
neuroarthropathy occurrence in patients with diabetic foot and type 2 diabetes.
MATERIALS: The study included 144 patients with type 2 diabetes; 33 with Charcot 
neuroarthropathy and 111 with diabetic foot of neuropathic origin without 
neuroarthropathy. The study was perform in Gastroenterology and Metabolic 
Diseases Department, Medical University of Warsaw, Poland.
RESULTS: The regression analysis showed that Charcot neuroarthropathy occurrence 
risk factors were: male gender (OR=4.94, 95% CI:1.63-15.03, p=0.003), age 
(OR=0.92, 95% CI:0.87-0.96, p=0.0001), diabetic foot duration (OR=1.19, 
95% CI:1.08-1.32, p=0.00002) and height (OR=1.078, 95% CI:1.019-1.140, p=0.007). 
A positive effect on Charcot neuroarthropathy presence was exerted by body 
weight (OR=1.027, 95% CI:1.003-1.051, p=0.03) and hips circumference (OR=1.034, 
95% CI:0.997-1.072, p=0.04).
CONCLUSIONS: The existence of the specific factors influencing Charcot 
neuroarthropathy development may result in earlier identification of patients at 
risk of its development. There is a necessity to take special care for patients 
prone to develop Charcot neuroarthropathy in order to prevent its occurrence and 
severe complications.