Blood, from slaughterhouses, is an inevitable part of meat production, causing 
environmental problems due to the large volumes recovered and its low 
valorization. However, the α137-141 peptide, a natural antimicrobial peptide, 
can be obtained after hydrolysis of hemoglobin, the main constituent of blood 
red part. To recover it at a sufficient concentration for antimicrobial 
applications, a new sustainable technology, called electrodialysis with 
ultrafiltration membrane (EDUF), was investigated. The α137-141 concentration 
was increased about 4-fold at a feed peptide concentration of 8% with an 
enrichment factor above 24-fold. This feed peptide concentration also needed the 
lowest relative energy consumption. Moreover, this peptide fraction protected 
meat against microbial growth, as well as rancidity, during 14 days under 
refrigeration. This peptide fraction was validated as a natural preservative and 
substitute for synthetic additives against food spoilage. Finally, producing 
antimicrobial/antioxidant peptide from wastes by EDUF fits perfectly with the 
concept of circular economy.