OBJECTIVE: We aimed to investigate the profiles and prognostic values of delayed 
cerebral ischemia (DCI) and delayed cerebral infarction.
METHODS: IMASH (Intravenous Magnesium Sulphate for Aneurysmal Subarachnoid 
Hemorrhage) was registered at http://www.strokecenter.org/trials , and 
http://www.ClinicalTrials.gov (NCT00124150). Data of 327 patients were retrieved 
for logistic regression analyses.
RESULTS: Seventy-one (22%) patients developed DCI, and 35 (11%) patients 
developed delayed cerebral infarction. Only 18 (25%) patients with DCI and 7/35 
(20%) patients with delayed cerebral infarction had mean middle cerebral artery 
velocities (transcranial Doppler ultrasound) over 120 cm/s. Regarding the 
prognostic significance of the components of DCI, delayed cerebral infarction 
predicted unfavorable outcome in terms of Extended Glasgow Outcome Scale (OR 
3.1, 95% [CI] 1.3-7.8), poor outcome in terms of modified Rankin Scale (odds 
ratio [OR] 3.0, 95% confidence interval CI 1.2-7.7), and dependent activity of 
daily living in terms of Barthel Index (OR 3.6, 95% CI 1.4-9.2) at 6 months, 
after adjustments for other prognostic factors. On the other hand, clinical 
deterioration predicted inpatient mortality (OR 8.8, 95% CI 1.6-48.8) after 
adjustments for other prognostic factors.
CONCLUSIONS: Delayed cerebral ischemia and delayed cerebral infarction carried 
different prognostic values in aneurysmal subarachnoid hemorrhage.