Author information:
(1)Whitehead Institute for Biomedical Research and Massachusetts Institute of 
Technology, Department of Biology, 9 Cambridge Center, Cambridge, MA 02142, USA. 
Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute 
of Technology, Cambridge, MA 02139, USA. Koch Institute for Integrative Cancer 
Research, 77 Massachusetts Avenue, Cambridge, MA 02139, USA. Broad Institute of 
Harvard and Massachusetts Institute of Technology, 7 Cambridge Center, 
Cambridge, MA 02142, USA.
(2)Harvard Medical School, 260 Longwood Avenue, Boston, MA 02115, USA.
(3)Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical 
School, 220 Longwood Avenue, Boston, MA 02115, USA.
(4)Whitehead Institute for Biomedical Research and Massachusetts Institute of 
Technology, Department of Biology, 9 Cambridge Center, Cambridge, MA 02142, USA. 
Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute 
of Technology, Cambridge, MA 02139, USA. Koch Institute for Integrative Cancer 
Research, 77 Massachusetts Avenue, Cambridge, MA 02139, USA. Broad Institute of 
Harvard and Massachusetts Institute of Technology, 7 Cambridge Center, 
Cambridge, MA 02142, USA. sabatini@wi.mit.edu.