DeQuervain's disease of the first dorsal compartment of the wrist, is a common 
wrist pathology, pain results from resisted gliding of the abductor pollicis 
longus and the extensor pollicis brevis tendon in the fibroosseous canal. 
Management of resistant cases of DeQuervain's disease with failed conservative 
treatment treated by surgical decompression yield satisfactory outcomes. A large 
number of patients being dissatisfied with the medical treatment, still present 
with persistent pain and positive clinical finding. Surgical decompression is an 
effective method for the treatment of resistant cases of DeQuervain's disease. 
Outcome variables were measured by Scheller, Forget and Macey evaluation 
criteria. Most of our patients were female 28(93.3%), housewife 17(56.7%) with 
mean age of 41.57 years, ranging from 25-60 years. Right sided involvement was 
20(66.7%) and Left sided involvement was 10(33.3%). Restricted movement of thumb 
in 30(100%) were the predominant symptoms. One (3.3%) patient develop chronic 
tenosynovitis, 1(3.3%) patient develop hypertrophic scar. There was no wound 
infection in the follow-up period of 3-18 months. Satisfactory results were 
found in 29(96.7%).