Influenza is an infectious disease caused by RNA viruses of the family 
Orthomyxoviridae. The new influenza H1N1 viral stain has emerged by the genetic 
combination of genes from human, pig, and bird's H1N1 virus. The influenza virus 
is roughly spherical and is enveloped by a lipid membrane. There are two 
glycoproteins in this lipid membrane; namely, hemagglutinin (HA) which helps in 
attachment of the viral strain on the host cell surface and neuraminidase (NA) 
that is responsible for initiation of viral infection. We have developed 
homology models of both Hemagglutinin and Neuraminidase receptors from H1N1 
strains in eastern India. The docking studies of B-Sialic acid and O-Sialic acid 
in the optimized and energy-minimized homology models show important H-bonding 
interactions with ALA142, ASP230, GLN231, GLU232, and THR141. This information 
can be used for structure-based and pharmacophore-based new drug design. We have 
also calculated ADME properties (Human Oral Absorption (HOA) and % HOA) for 
Oseltamivir which have been subject of debate for long.