The outstanding regenerative capacity of skeletal muscle is attributed to the 
resident muscle stem cell termed satellite cell. Satellite cells are essential 
for skeletal muscle regeneration as they ultimately provide the myogenic 
precursors that rebuild damaged muscle tissue. Satellite cells 
characteristically are a heterogeneous population of stem cells and committed 
progenitor cells. Delineation of cellular hierarchy and understanding how 
lineage fate choices are determined within the satellite cell population will be 
invaluable for the advancement of muscle regenerative therapies.