We report 7 children who received gabapentin (GBP) as adjunctive medic ation and 
subsequently developed behavioral side effects. These behavioral changes 
consisted of intensification of baseline behaviors as well as new behavioral 
problems. Behaviors that parents considered most troublesome were tantrums, 
aggression directed toward others, hyperactivity, and defiance. All behavioral 
changes were reversible and were managed by dose reduction or discontinuation of 
GBP. All children had baseline attention deficit hyperactivity disorder and 
developmental delays.