Amblyopia is characterised by decrease in vision in one or both eyes as a result 
of processing defect in the visual pathways of the brain. It is considered an 
irreversible process if detected in the adult age group. This study was 
conducted from July 1 to December 31, 2010, at Shifa Foundation Community Health 
Centre, Islamabad, to determine if anisometropic amblyopia detected in adults 
can be reversed. A total of 15 adults, 11 (73.33%) males and 4 (26.66%) females, 
were managed for anisometropic amblyopia. All the patients were prescribed full 
cycloplegic correction in the anisometropic eye simultaneously with part-time 
occlusion therapy. Success was defined as visual acuity of 6/18 or better at the 
end of the therapy. All patients were required to complete a structured 
questionnaire regarding their experiences with the therapy. Reversal of 
amblyopia was observed in 11 (73.33%) patients who felt more confident about 
performing tasks for which they had earlier considered themselves unsuitable. 
Poor compliance was responsible for not producing the desired outcome in 4 
(26.66%) patients. Anisometropic amblyopia in adults is reversible with 
dedicated efforts on behalf of both the ophthalmologist and the patient.