PURPOSE: To report a case of idiopathic retinal vasculitis, aneurysms and 
neuroretinitis (IRVAN) syndrome associated with positive perinuclear 
antineutrophil cytoplasmic antibody (P-ANCA).
CASE REPORT: A 51-year-old man presented with loss of vision in his right eye 
since many years ago and blurred vision in his left eye over the past year. 
Ophthalmologic examination revealed optic atrophy and old vascular sheathing in 
the right eye and blurred disc margin, macular exudation, flame shaped 
hemorrhages, retinal vascular sheathing and multiple aneurysms at arterial 
bifurcation sites in the left eye, findings compatible with IRVAN syndrome. On 
systemic workup, the only notable finding was P-ANCA positivity.
CONCLUSION: IRVAN syndrome may be a retinal component of P-ANCA associated 
vasculitis.