Conflict of interest statement: Conflicts of interest:EMO: Consultancy: Onyx; 
Bristol Myers Squibb; Array Pharmaceuticals. Research Funding: Celgene; Onyx; 
Pharmamar; Array Pharmaceuticals. PGR. Consultancy: Celgene; Millennium Takeda; 
Johnson & Johnson; Novartis; Bristol Myer Squibb. Research Funding: Celgene and 
Millenium. SVR: No conflicts to disclose. AP: Consultancy & Honoraria: Amgen; 
Bristol Myers Squibb; Celgene; Janssen-Cilag; Millennium; ONYX. MVM: 
Consultancy: Janssen-Cilag; Celgene; Millennium. RO: Consultancy: Abbott 
Laboratories; Centocor Ortho Biotech; Cephalon; Millennium; Novartis; Onyx. 
Research Funding: Celgene; Johnson and Johnson; Millennium; Onyx. SK: 
Consultancy: Millennium; Celgene; Onyx. Research Funding: Celgene; Millennium; 
Novartis; Celphalon; Sanofi; Onyx. SU: Consultancy: Celgene. Honoraria: Celgene; 
Onyx. Research Funding: Celgene; Onyx; Millennium. DR: Honoraria: Amgen. 
Research Funding: Eli Lilly. RN: Consultancy: Onyx; Millennium; Celgene. 
Honoraria: Onyx; Millennium; Celgene. Research Funding: Onyx; Millennium; 
Celgene. HE: Consultancy: Celgene; Janssen. Honoraria: Celgene; Janssen. 
Research Funding: Celgene; Janssen. KCA: Consultancy: Gilead; Sanofi-Aventis; 
Onyx; Celgene. Stock Ownership; Acetylon; Oncoprep. MAD: Consultancy: Celgene; 
Ortho Biotech. Honoraria: Celgene; Ortho Biotech. Research Funding: Celgene. HA: 
Honoraria: Celgene; Janssen; Onyx. UHM: Honoraria: Celgene; Janssen-Cilag. IT: 
No conflicts to disclose. GM: Consultancy: Millennium-Takeda; Neotype. 
Honoraria: Millennium-Takeda; Pfizer. RS: No conflicts to disclose. PM: 
Consultancy: Celgene; Janssen. Honoraria: Celgene; Janssen. PLB: Honoraria: 
Onyx. CSC: No conflicts to disclose. JJL: Honoraria: Celgene. Research Funding: 
Celgene; Janssen-Cilag. JS; Research Funding: Janssen-Cilag; Celgene; Onyx. AR: 
Consultancy: Celgene. Research Funding: Celgene; Bristol Myers Squibb; 
Millennium; Astra Zeneca; Onyx. JM: Research Funding: Celgene; Onyx; Sanofi. SZ: 
Research Funding: Celgene; Janssen-Cilag; Millennium. SL: Consultancy: Celgene; 
Millennium; Novartis; Bristol Myers Squibb; Onyx; Janssen-Cilag. RC: 
Consultancy: Millennium. Research Funding: Millennium; Prothena Biotech. WJC: 
Honoraria: Janssen; Celgene; Novartis. Research Funding: Celgene; Roche. PM: 
Consultancy: Celgene; Janssen; Millennium. Honoraria: Celgene; Janssen. PS: 
Research Funding: Janssen-Cilag; Celgene; Onyx. HL: Honoraria: Celgene; Mundi 
Pharma; Janssen-Cilag. Research Funding: Celgene; Mundi-Pharma; Janssen-Cilag. 
BD: Honoraria: Celgene Corporation; Onyx Pharmaceutical; Millennium 
Pharmaceutical, The Takeda Company. JFSM: Consultancy & Honoraria: 
Janssen-Cilag; Millennium; Celgene; Onyx; Novartis; Bristol Myers Squibb