Colorectal cancer (CRC) is the 3rd most common type of cancer worldwide. Late 
detection plays role in one-third of annual mortality due to CRC. Therefore, it 
is essential to find a precise and optimal diagnostic and prognostic biomarker 
for the identification and treatment of colorectal tumorigenesis. Covalently 
closed, circular RNAs (circRNAs) are a class of non-coding RNAs, which can have 
the same function as microRNA (miRNA) sponges, as regulators of splicing and 
transcription, and as interactors with RNA-binding proteins (RBPs). Therefore, 
circRNAs have been investigated as specific targets for diagnostic and 
prognostic detection of CRC. These non-coding RNAs are also linked to 
metastasis, proliferation, differentiation, migration, angiogenesis, apoptosis, 
and drug resistance, illustrating the importance of understanding their 
involvement in the molecular mechanisms of development and progression of CRC. 
In this review, we present a detailed summary of recent findings relating to the 
dysregulation of circRNAs and their potential role in CRC.