In this review report, current possibilities of evaluation of quality of life in 
Parkinson's disease have been critically presented. Health Related Quality of 
Life (-HRQoL) comprises a wide spectrum of consequences of the disease. 
Measurement of quality of life has become increasingly relevant as an outcome 
parameter, especially in long-term trials. Most of the available QoL instruments 
depend on patient self-reports. The data can be collected by written 
questionnaires. There are universal questionnaires of QoL--for many diseases and 
the specific ones--specially created for one disease. Among universal 
questionnaires, the Sickness Impact Profile (SIP) and the Short-Form Health 
Status Survey (SF-36) are the most popular in Parkinson's disease. As for 
specific questionnaires: the Parkinson`s Disease Questionnaire (PDQ-39) and the 
Parkinson's Disease Quality of Life Questionnaire (PDQL) have been described.