Isolated Left Ventricular Non Compaction Cardiomyopathy (LVNCC) is a rare 
genetic cardiomyopathy characterized by a thickened left ventricle with two 
distinct layers - an inner noncompacted (spongy) layer and an outer compact 
(dense) layer. The spongy layer is composed of deep intertrabecular recesses. 
Familial and sporadic forms are known to exist and there is significant genetic 
heterogeneity among the inherited forms. Symptoms vary and range from 
asymptomatic to severe heart failure and sudden death. The clinical diagnosis of 
LVNCC can be challenging partly because there is currently no consensus for 
diagnostic criteria. As such, many affected individuals are, inopportunely, 
first diagnosed at post-mortem examination.