Miller Fisher syndrome is an acute inflammatory polyradiculoneuropathy that is 
generally considered a variant of Guillain-Barré syndrome and is characterized 
by the clinical triad of ataxia, areflexia, and ophthalmoplegia. Several reports 
of familial Guillain-Barré syndrome have been reported, indicating a possible 
underlying genetic and/or environmental predisposition to the development of 
Guillain-Barré syndrome. A familial association in Miller Fisher syndrome has 
not previously been described in the literature. We report 2 cases of Miller 
Fisher syndrome presenting simultaneously in siblings, with a review of recent 
relevant literature.