Sudden unexpected death in epilepsy (SUDEP) remains a leading cause of 
epilepsy-related death, and yet, its pathogenic mechanisms remain ill-defined. 
Although epidemiological studies of SUDEP in heterogenous populations have 
established a number of clinical associations, evaluation and stratification of 
individual risk remains difficult. Thus, potential markers as predictors of risk 
of SUDEP are important not only clinically but also for research on SUDEP 
prevention. Recordings from rare monitored cases of SUDEP demonstrate postictal 
generalized EEG suppression after terminal seizures, raising expectations that 
postictal generalized EEG suppression may identify individuals at higher risk. 
In this review, we consider the literature on postictal generalized EEG 
suppression and evaluate its relevance and utility as a possible marker of 
SUDEP.