alpha-Galactosidase and beta-galactosidase activities have been determined in 
leukocyte preparations from 100 randomly selected Chinese adults. For 
alpha-galactosidase, two groups with low activities were identified: group I 
consisted of 3 females having activities below 40% of normal, and group II 
consisted of 5 males and 1 female with activities about 60% of normal. Family 
studies suggested that these low alpha-galactosidase activities are genetically 
determined. Only 1 individual was found to have about 50% of normal 
beta-galactosidase activity; presumably he is a carrier for beta-galactosidase 
deficiency (GM1 gangliosidosis).