Nephrotic syndrome represents a constellation of symptoms including 
hyperalbuminuria, hypoalbuminemia, edema formation, hypercholesterolemia, 
hypertension, hypercoagulopathy, and increased infection risk. The hallmark of 
this syndrome is proteinuria greater than 3.5 grams per 24 hours, and the 
clinical features are secondary manifestations of an underlying primary 
glomerular or systemic disease. The objectives of treatment are threefold: 
correcting the primary disease, decreasing the symptoms and secondary effects 
associated with this syndrome, and preventing complications. This article 
presents a case report of a man diagnosed with nephrotic syndrome secondary to 
amyloidosis. The clinical aspects of the disease processes, the diagnostic 
evaluation, the treatment course, and disease management are discussed.