Primary intestinal lymphangiectasia (PIL) is a rare protein-losing enteropathy 
with lymphatic leakage into the small intestine. Dilated lymphatics in the small 
intestinal wall and mesentery are observed in this disease. Laboratory tests of 
PIL patients revealed hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia 
and increased stool α-1 antitrypsin clearance. Cell-mediated immunodeficiency is 
also present in PIL patients because of loss of lymphocytes. As a result, the 
patients are vulnerable to chronic viral infection and lymphoma. However, cases 
of PIL with chronic viral infection, such as human papilloma virus-induced 
warts, are rarely reported. We report a rare case of PIL with generalized warts 
in a 36-year-old male patient. PIL was diagnosed by capsule endoscopy and 
colonoscopic biopsy with histological tissue confirmation. Generalized warts 
were observed on the head, chest, abdomen, back, anus, and upper and lower 
extremities, including the hands and feet of the patient.