INTRODUCTION: Haemophilic pseudotumour (HP) is an encapsulated haematoma in 
patients with haemophilia (PWH) which has a tendency to progress and produce 
clinical symptoms related to its anatomical location.
AIM: To show the experience of one surgeon who has been using mini-invasive 
technique to treat pseudotumours of limbs in PWH with and without inhibitors at 
one centre for 28 years.
MATERIALS AND METHODS: Thirty-three patients with 39 HP were treated. All 
patients had haemophilia A. Twenty-four patients had no inhibitors (72.8%), and 
9 had inhibitors (27.2%). The mean follow-up was 16 years (1-25). All patients 
had x-rays and MRIs. All of them received Buenos Aires protocol as conservative 
treatment for 6 weeks. MRIs were repeated after 6 weeks' treatment to assess 
response to treatment. Surgery was performed in patients who did not respond to 
conservative treatment.
RESULTS: After Buenos Aires protocol, four pseudotumours did not shrink 
(10.24%), 33 (84.61%) shrank, and two (5.12%) healed. Thirty-seven pseudotumours 
had surgery, 35 pseudotumours (94.59%) healed with minimally invasive treatment, 
and two did not heal (5.41%). No infection was observed with this treatment. The 
mortality rate for the series was 0%.
CONCLUSION: The minimally invasive treatment of pseudotumours was effective in 
95% of the cases and resulted in no mortality in this series after 28 years.