We report a 72-year-old woman with overlapping Miller Fisher syndrome (MFS), 
Guillain-Barré syndrome (GBS) and Bickerstaff's brainstem encephalitis (BBE). 
She developed diplopia and unsteady gait a week after an upper respiratory 
infection on day 1. She had weakness of both upper limbs on day 3 and became 
drowsy, and her respiratory status worsened on day 5. Neurologic examination 
revealed ophthalmoplegia, ataxia, symmetrical weakness, areflexia, and 
consciousness disturbance. We diagnosed her with MFS on day 1, GBS on day 3 and 
overlapping BBE on day 5. She underwent immunoadsorption therapy and two courses 
of intravenous immunoglobulin therapy. Ten months after onset, her symptoms had 
fully recovered. Anti-GM1 IgG, GD1a IgG, GQ1b IgG, and GT1a IgG antibodies were 
positive. Our case supports the notion that MFS, GBS, and BBE are all part of a 
continuous clinical spectrum, which is an antibody-mediated process.