A double-blind study of terodiline compared with placebo was performed in 58 
children aged 6 to 14 years with urgency or urge incontinence. All had an 
unstable bladder at cystometry. A bladder regimen was emphasised during the 
study. Continence was improved according to micturition charting and a pad test 
in both groups. Terodiline at 25 mg/day, however, gave significantly better 
results than placebo. In patients with a subnormal bladder capacity (less than 
or equal to 150 ml), a significant increase in capacity was recorded on 
cystometry during medication with terodiline but not with placebo. The improved 
continence seen in the placebo group was probably due to the non-specific 
bladder training achieved by the child's increased awareness and adult 
involvement during treatment. The even better results attained in the terodiline 
group shows this drug to be a valuable adjunct to a bladder regimen in children 
with urge incontinence, particularly since no important adverse effects were 
noted during an 8-week period.