BACKGROUND AND AIM: Duodenal ulcer bleeding has a higher risk of mortality than 
bleeding from other portions of the gastrointestinal tract. AIMS65 is an 
effective risk-scoring system to predict prognosis of upper gastrointestinal 
bleeding and can be easily calculated without endoscopic findings. In this 
study, we investigate the usefulness of AIMS65 to predict prognosis of patients 
with duodenal ulcer bleeding.
METHODS: Two hundred and fifty-five patients with endoscopically diagnosed 
duodenal ulcer bleeding at Kurashiki Central hospital from July 2007 to June 
2017 were studied. We compared AIMS65, Glasgow Blatchford score (GBS), admission 
Rockall, and full Rockall scoring systems for predicting in-hospital mortality 
by calculating area under the receiver operating characteristic curve (AUROC).
RESULTS: In-hospital mortality due to duodenal ulcer bleeding occurred in 17 
(6.7%). Scores of all scoring systems were significantly higher in patients with 
in-hospital mortality than in patients without it. AUROC values for predicting 
in-hospital mortality was 0.83 in AIMS65, 0.74 in GBS, 0.76 in admission Rockall 
score, and 0.82 in full Rockall score, a statistically insignificant difference 
among the systems. In AIMS65, score more than or equal to 2 was an optimal value 
to predict in-hospital mortality, with sensitivities of 88.2% and specificities 
of 59.7%, respectively.
CONCLUSIONS: AIMS65 predicted in-hospital mortality of patients with duodenal 
ulcer bleeding as accurately as did other scoring systems. Given its simplicity 
of calculation, AIMS65 may be a more clinically practical system in the 
management of bleeding duodenal ulcer patients.