Behçet syndrome is a chronic disease hallmarked by inflammation of the blood 
vessels that is related to an autoimmune reaction caused by inherited 
susceptibility due to specific genes and environmental factors, probably 
components of infectious microorganisms, which turn on or get going the disease 
in genetically susceptible subjects. The more common clinical expression of the 
disease is represented by a triple-symptom complex of recurrent oral aphthous 
ulcers, genital ulcers, and uveitis, sometimes associated with inflammatory 
arthritis, phlebitis, iritis, as well as inflammation of the digestive tract, 
brain, and spinal cord. The treatment strategies used to manage the 
manifestations of Behçet syndrome have gradually progressed, and a number of new 
therapeutic resources have been implemented in recent years, allowing better 
control of pathogenic mechanisms, reducing symptoms and suffering, and 
ameliorating patient's outcome.