During the past years, the advances in high-throughput technologies have 
produced an unprecedented growth in the number and size of repositories and 
databases storing relevant biological data. Today, there is more biological 
information than ever but, unfortunately, the current status of many of these 
repositories is far from being optimal. Some of the most common problems are 
that the information is spread out in many small databases; frequently there are 
different standards among repositories and some databases are no longer 
supported or they contain too specific and unconnected information. In addition, 
data size is increasingly becoming an obstacle when accessing or storing 
biological data. All these issues make very difficult to extract and integrate 
information from different sources, to analyze experiments or to access and 
query this information in a programmatic way. CellBase provides a solution to 
the growing necessity of integration by easing the access to biological data. 
CellBase implements a set of RESTful web services that query a centralized 
database containing the most relevant biological data sources. The database is 
hosted in our servers and is regularly updated. CellBase documentation can be 
found at http://docs.bioinfo.cipf.es/projects/cellbase.