CASES: We present four cases of ocular melanosis. Choroidal melanoma was 
detected in all of them. Three eyes had decreased visual acuity and were 
enucleated because of their large, active tumours. In the fourth case the 
melanoma was detected in a routine examination and we were able to apply a 
preserving treatment with I125 brachytherapy.
DISCUSSION: Melanosis oculi is often underestimated as a risk factor for uveal 
melanoma and glaucoma. Ophthalmic surveillance, every 6 or 12 months is 
important, in patients with ocular melanocytosis for early detection of high 
risk diseases.