Anxiety is common among adolescents with autism spectrum disorders (ASD) and may 
amplify the core social disability, thus necessitating combined treatment 
approaches. This pilot, randomized controlled trial evaluated the feasibility 
and preliminary outcomes of the Multimodal Anxiety and Social Skills 
Intervention (MASSI) program in a sample of 30 adolescents with ASD and anxiety 
symptoms of moderate or greater severity. The treatment was acceptable to 
families, subject adherence was high, and therapist fidelity was high. A 16 % 
improvement in ASD social impairment (within-group effect size = 1.18) was 
observed on a parent-reported scale. Although anxiety symptoms declined by 26 %, 
the change was not statistically significant. These findings suggest MASSI is a 
feasible treatment program and further evaluation is warranted.