obo_vocabulary resource [obo_vocabulary:Resource]
format version [obo_vocabulary:format-version]
format version
date [obo_vocabulary:date]
date
saved by [obo_vocabulary:saved-by]
saved by
auto generated by [obo_vocabulary:auto-generated-by]
auto generated by
default namespace [obo_vocabulary:default-namespace]
default namespace
ontology [obo_vocabulary:ontology]
ontology
remark [obo_vocabulary:remark]
remark
Editors: Wen J. Chen & Daniela Raciti, WormBase, Caltech
wbls resource [wbls_vocabulary:Resource]
all stages Ce [wbls:0000002]
all stages Ce
All C. elegans development stages, including embryo, larva and adult stage. [wb:wjc]
embryo Ce [wbls:0000003]
embryo Ce
The whole period of embryogenesis, from the formation of an egg till its hatch. [wb:wjc]
proliferating embryo Ce [wbls:0000004]
proliferating embryo Ce
0-350min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 560 cells. From start of first cleavage till cleavage is over. [wb:wjc]
part_of [obo_vocabulary:part_of]
part_of
blastula embryo Ce [wbls:0000005]
blastula embryo Ce
0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage till the start of gastrulation. [wb:wjc]
1-cell embryo Ce [wbls:0000006]
1-cell embryo Ce
Also called zygote. -50min till 0min of first cleavage at 20 Centigrade. Contains 1 cell. [wb:wjc]
2-cell embryo Ce [wbls:0000007]
2-cell embryo Ce
0-20min after first cleavage at 20 Centigrade. Contains 2 cells. [wb:wjc]
starts_at_end_of [obo_vocabulary:starts_at_end_of]
starts_at_end_of
4-cell embryo Ce [wbls:0000008]
4-cell embryo Ce
20-40min after first cleavage at 20 Centigrade. Contains 4 cells. [wb:wjc]
28-cell embryo Ce [wbls:0000009]
28-cell embryo Ce
100-105 min after first cleaveage at 20 Centigrade. Contains 28 cells. [wb:wjc]
gastrulating embryo Ce [wbls:0000010]
gastrulating embryo Ce
100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation. [wb:wjc]
51-cell embryo Ce [wbls:0000011]
51-cell embryo Ce
120-135 min after first cleavage at 20 Centigrade. Contains 51 cells. [wb:wjc]
preceded_by [obo_vocabulary:preceded_by]
preceded_by
88-cell embryo Ce [wbls:0000012]
88-cell embryo Ce
145-150 min after first cleavage at 20 Centigrade. Contains 88 cells. [wb:wjc]
enclosing embryo Ce [wbls:0000013]
enclosing embryo Ce
290-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage when embryo just finished gastulation and is enclosing. [wb:wjc]
late cleavage stage embryo Ce [wbls:0000014]
late cleavage stage embryo Ce
210-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage before the fast cleavage of cells finishes. [wb:wjc]
elongating embryo Ce [wbls:0000015]
elongating embryo Ce
350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation till elongation is over. [wb:wjc]
bean embryo Ce [wbls:0000016]
bean embryo Ce
350-390min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. Emrbyo elongation started but have not formed comma shape yet. The shape of embryo looks like a lima bean. A stage right before comma embryo. Also called lima embryo or lima bean stage. [wb:wjc]
comma embryo Ce [wbls:0000017]
comma embryo Ce
390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo. [wb:wjc]
1.5-fold embryo Ce [wbls:0000018]
1.5-fold embryo Ce
420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo. [wb:wjc]
2-fold embryo Ce [wbls:0000019]
2-fold embryo Ce
460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo. [wb:wjc]
3-fold embryo Ce [wbls:0000020]
3-fold embryo Ce
520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage. [wb:wjc]
fully-elongated embryo Ce [wbls:0000021]
fully-elongated embryo Ce
620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo. [wb:wjc]
postembryonic Ce [wbls:0000022]
postembryonic Ce
The stage after hatch till death. [wb:wjc]
larva Ce [wbls:0000023]
larva Ce
From the time after hatch till becomes adult. [wb:wjc]
L1 larva Ce [wbls:0000024]
L1 larva Ce
The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. [wb:wjc]
L1-L2 lethargus Ce [wbls:0000025]
L1-L2 lethargus Ce
The stage during L1-L2 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
L1-L2 molt Ce [wbls:0000026]
L1-L2 molt Ce
The stage when an animal shifts from L1 larva to L2 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
L2 larva Ce [wbls:0000027]
L2 larva Ce
The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. [wb:wjc]
L2-L3 lethargus Ce [wbls:0000028]
L2-L3 lethargus Ce
The stage during L2-L3 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
L2-L3 molt Ce [wbls:0000029]
L2-L3 molt Ce
The stage when an animal shifts from L2 larva to L3 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
L2d-dauer lethargus Ce [wbls:0000030]
L2d-dauer lethargus Ce
The stage during L2d-dauer molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
L2d-dauer molt Ce [wbls:0000031]
L2d-dauer molt Ce
The stage when an animal shifts from L2d larva to dauer larva. It includes the synthesis of new cuticle, cease of pharyngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
dauer larva Ce [wbls:0000032]
dauer larva Ce
A third stage larva specialized for dispersal and long term survival. [ISBN:0-87969-433-5]
postdauer-L4 lethargus Ce [wbls:0000033]
postdauer-L4 lethargus Ce
The stage during postdauer-L4 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
postdauer-L4 molt Ce [wbls:0000034]
postdauer-L4 molt Ce
The stage when an animal shifts from post dauer stage to L4 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
L3 larva Ce [wbls:0000035]
L3 larva Ce
The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. [wb:wjc]
L3-L4 lethargus Ce [wbls:0000036]
L3-L4 lethargus Ce
The stage during L3-L4 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
L3-L4 molt Ce [wbls:0000037]
L3-L4 molt Ce
The stage when an animal shifts from L3 larva to L4 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
L4 larva Ce [wbls:0000038]
L4 larva Ce
The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. [wb:wjc]
L4-adult lethargus Ce [wbls:0000039]
L4-adult lethargus Ce
The stage during L4-adult molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
L4-adult molt Ce [wbls:0000040]
L4-adult molt Ce
The stage when an animal shifts from L4 larva to adult. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
adult Ce [wbls:0000041]
adult Ce
The stage after an animal is fully-developed and reaches maturity. [wb:wjc]
L1-L2 ecdysis Ce [wbls:0000042]
L1-L2 ecdysis Ce
The stage during L1-L2 molt, after the brief lethargus period, when an animal sheds off old cuticle. [wb:wjc]
L1-L2d molt Ce [wbls:0000043]
L1-L2d molt Ce
The stage when an animal shifts from L1 larva to L2d larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
L1-L2d lethargus Ce [wbls:0000044]
L1-L2d lethargus Ce
The stage during L1-L2d molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
L1-L2d ecdysis Ce [wbls:0000045]
L1-L2d ecdysis Ce
The stage during L1-L2d molt, after the brief lethargus period, when an animal sheds off old cuticle. [wb:wjc]
L2d larva Ce [wbls:0000046]
L2d larva Ce
A special second stage larva with altered physiology and developmental potential that leads to formation of dauer larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. [ISBN:0-87969-433-5]
L2-L3 ecdysis Ce [wbls:0000047]
L2-L3 ecdysis Ce
The stage during L2-L3 molt, after the brief lethargus period, when an animal sheds off old cuticle. [wb:wjc]
L2d-dauer ecdysis Ce [wbls:0000048]
L2d-dauer ecdysis Ce
The stage during L2d-dauer molt, after the brief lethargus period, when an animal sheds off old cuticle. [wb:wjc]
L3-L4 ecdysis Ce [wbls:0000049]
L3-L4 ecdysis Ce
The stage during L3-L4 molt, after the brief lethargus period, when an animal sheds off old cuticle. [wb:wjc]
L4-adult ecdysis [wbls:0000050]
L4-adult ecdysis
The stage during L4-adult molt, after the brief lethargus period, when an animal shed off old cuticle. [wb:wjc]
postdauer-L4 ecdysis Ce [wbls:0000051]
postdauer-L4 ecdysis Ce
The stage during postdauer-L4 molt, after the brief lethargus period, when an animal sheds off old cuticle. [wb:wjc]
post dauer stage Ce [wbls:0000052]
post dauer stage Ce
The stage right after an animal recovered from dauer but has not started transformation to L4 larva yet. [wb:wjc]
L2d-L3 molt Ce [wbls:0000053]
L2d-L3 molt Ce
The stage when an animal shifts from L2d larva to L3 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle. [wb:wjc]
L2d-L3 lethargus Ce [wbls:0000054]
L2d-L3 lethargus Ce
The stage during L2d-L3 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old. [wb:wjc]
L2d-L3 ecdysis Ce [wbls:0000055]
L2d-L3 ecdysis Ce
The stage during L2d-L3 molt, after the brief lethargus period, when an animal sheds off old cuticle. [wb:wjc]
adult male Ce [wbls:0000056]
adult male Ce
The stage after an male animal is fully-developed and reaches maturity. [wb:wjc]
adult hermaphrodite Ce [wbls:0000057]
adult hermaphrodite Ce
The stage after an hermaphrodite animal is fully-developed and reaches maturity. [wb:wjc]
pre-reproductive stage adult hermaphrodite Ce [wbls:0000058]
pre-reproductive stage adult hermaphrodite Ce
Very young adult hermaphrodites that do not have eggs in the uterus yet. At 20 Centigrade: 0 - 13 hours after L4-adult molt. 3 days after first cleaveage. [wb:wjc]
reproductive stage adult hermaphrodite Ce [wbls:0000060]
reproductive stage adult hermaphrodite Ce
Adult hermaphrodites continuously laying fertilized eggs. Hermaphrodite in egg laying stages--usually up to 4/5 days after L4-adult molt at Centigrade. From the first fertilized egg is laid, till all sperms are used. At 20 Centigrade: 13 hours after L4-adult molt until about 5.4 days after the L4-adult molt. 3-8.4 days after first cleavage. [wb:wjc]
oocyte-laying stage adult hermaphrodite Ce [wbls:0000061]
oocyte-laying stage adult hermaphrodite Ce
When egg-laying is still going on but intermittent and during which a significant number of oocytes are laid. Included in reproductive stage adult hermaphrodite. [wb:wjc]
post-reproductive stage adult hermaphrodite Ce [wbls:0000062]
post-reproductive stage adult hermaphrodite Ce
Adult hermaphrodites that contain no more sperm, thus stop egg-laying, but still alive. At 20 Centigrade: 5.4 days after L4-adult molt until the death. 8.4 - 13.2 (average wild type life span) days after first cleavage. [wb:wjc]
newly molted young adult hermaphrodite Ce [wbls:0000063]
newly molted young adult hermaphrodite Ce
At 20 Centigrade: 0-24 hours after L4-adult molt. [wb:wjc]
1-day post-L4 adult hermaphrodite Ce [wbls:0000064]
1-day post-L4 adult hermaphrodite Ce
At 20 Centigrade: 24-48 hours after L4-adult molt. 4-5 days after first cleavage. [wb:wjc]
2-days post-L4 adult hermaphrodite Ce [wbls:0000065]
2-days post-L4 adult hermaphrodite Ce
At 20 Centigrade: 48-72 hours after L4-adult molt. 5-6 days after first cleavage. [wb:wjc]
3-days post-L4 adult hermaphrodite Ce [wbls:0000066]
3-days post-L4 adult hermaphrodite Ce
At 20 Centigrade: 72-96 hours after L4-adult molt. 6-7 days after first cleavage. [wb:wjc]
4-days post-L4 adult hermaphrodite Ce [wbls:0000067]
4-days post-L4 adult hermaphrodite Ce
At 20 Centigrade: 96-120 hours after L4-adult molt. 7-8 days after first cleavage. [wb:wjc]
5-days post-L4 adult hermaphrodite Ce [wbls:0000068]
5-days post-L4 adult hermaphrodite Ce
At 20 Centigrade: 5-6 days after L4-adult molt. 8-9 days after first cleavage. [wb:wjc]
4-7 days post-L4 adult hermaphrodite Ce [wbls:0000069]
4-7 days post-L4 adult hermaphrodite Ce
At 20 Centigrade: 4-7 days after L4-adult molt. 7-10 days after first cleavage. [wb:wjc]
7-10 days post-L4 adult hermaphrodite Ce [wbls:0000070]
7-10 days post-L4 adult hermaphrodite Ce
At 20 Centigrade: 7-10 days after L4-adult molt. 10-13 days after first cleavage. [wb:wjc]
8-cell embryo Ce [wbls:0000071]
8-cell embryo Ce
~50 min after first cleavage at 20 Centigrade. Contains 8 cells. [wb:wjc]
12-cell embryo Ce [wbls:0000072]
12-cell embryo Ce
~55 min after first cleavage at 20 Centigrade. Contains 12 cells. [wb:wjc]
L4 larva male Ce [wbls:0000073]
L4 larva male Ce
The fourth stage larva male. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. [wb:wjc]
11-15 days post-L4 adult hermaphrodite [wbls:0000074]
11-15 days post-L4 adult hermaphrodite
At 20 Centigrade: 11-15 days after L4-adult molt. 14-18 days after first cleavage. [wb:dr]
created_by [obo_vocabulary:created_by]
created_by
creation_date [obo_vocabulary:creation_date]
creation_date
Nematoda Life Stage [wbls:0000075]
Nematoda Life Stage
sheathed microfilaria Bma [wbls:0000077]
sheathed microfilaria Bma
Microfilaria is the stage which develops from the egg and precedes the L1 stage. The larvae are surrounded by a membrane thought to be derived from the vitelline membrane. [wb:dr&mb]
exact_synonym [obo_vocabulary:exact_synonym]
exact_synonym
unsheathed microfilariae Bma [wbls:0000078]
unsheathed microfilariae Bma
In the mosquito, the microfilariae shed sheaths, penetrate the midgut, and migrate to the thoracic muscles were the microfilariae increase in size, molt, and develop into infective larvae (L1 and L3) over a span of 7-21 days. [WB:dr&mb]
L1 larva Bma [wbls:0000079]
L1 larva Bma
L2 larva Bma [wbls:0000080]
L2 larva Bma
The second stage larva. Derived from flight muscles of vector host; some development in vitro, with L1 to L2 moulting, has been demonstrated but rarely; these are often staged by hours or days post blood meal. [wb:dr&mb]
L3 larva Bma [wbls:0000081]
L3 larva Bma
L4 larva Bma [wbls:0000082]
L4 larva Bma
The fourth stage larva. Should be conditioned by days post infection; as moulting is not synchronous, some samples are defined as L3/L4, indicating a mix of individuals as late L3, moulting, and early L4. [wb:dr&mb]
adult Bma [wbls:0000083]
adult Bma
Adults (or at least adult females) can live for 10 years in a human host, and can outlive their rodent laboratory hosts; it is usual to state the chronological age of the nematodes in days or months post-infection, and occasionally post-patency (the production of first microfilariae). [WB:dr&mb]
14-cell embryo Ce [wbls:0000084]
14-cell embryo Ce
E-cell has divided into Ea and Ep. Contains 14 cells. [wb:dr]
comment [obo_vocabulary:comment]
comment
Levin M, Hashimshony T, Wagner F, Yanai I. Developmental milestones punctuate gene expression in the Caenorhabditis embryo. Dev Cell. 2012 May 15;22(5):1101-8. Epub 2012 May 3. PubMed PMID: 22560298. Supplementary table 1.
24-cell embryo Ce [wbls:0000085]
24-cell embryo Ce
Fourth cleavage of the AB lineage. Contains 24 cells. [wb:dr]
44-cell embryo Ce [wbls:0000086]
44-cell embryo Ce
Fifth cleavage of the AB lineage. Contains 44 cells. [wb:dr]
68-cell embryo Ce [wbls:0000087]
68-cell embryo Ce
Sixth cleavage of the AB lineage. Contains 68 cells. [wb:dr]
86-cell embryo Ce [wbls:0000088]
86-cell embryo Ce
Seventh cleavage of the AB lineage. Contains 86 cells. [wb:dr]
190-cells embryo Ce [wbls:0000089]
190-cells embryo Ce
P4 and M cells have finished migrating. Contains 190 cells. [wb:dr]
96-cell embryo Ce [wbls:0000090]
96-cell embryo Ce
155-165 min after first cleavage at 20 Centigrade. Contains 96 cells. [wb:dr]
all stages Bma [wbls:0000091]
all stages Bma
All B. malayi developmental stages, including embryo, larva and adult stage. [wb:dr&mb]
embryo Bma [wbls:0000092]
embryo Bma
The whole period of embryogenesis, from the formation of an egg till its hatch. [WB:dr]
postembryonic Bma [wbls:0000093]
postembryonic Bma
The stage after hatch till death. [WB:dr]
early embryo Bma [wbls:0000094]
early embryo Bma
Proliferates from 1 to 100 cells. As the Brugia female reproductive tract is long (>10 cm), it is possible to dissect it and select early embryos just by isolating early parts of the post-spermatheca uterus. [WB:dr&mb]
middle embryo Bma [wbls:0000095]
middle embryo Bma
Proliferates from 100 cells to Lima bean stage. [WB:dr&mb]
late embryo Bma [wbls:0000096]
late embryo Bma
larva Bma [wbls:0000097]
larva Bma
From the time after hatch till becomes adult. [WB:dr]
vector-derived L3 Bma [wbls:0000098]
vector-derived L3 Bma
Also known as infective L3, or iL3; i.e. isolated from the vector salivary glands; these samples may-should be conditioned by age, which is usually counted in days from the blood meal. [wb:dr&mb]
related_synonym [obo_vocabulary:related_synonym]
related_synonym
post-infection L3 Bma [wbls:0000099]
post-infection L3 Bma
Derived from the host after reintroduction by vector feeding or manual inoculation; these piL3 samples are often-should be conditioned by age (hours or days post-infection). [wb:dr&mb]
young adult Bma [wbls:0000100]
young adult Bma
The animals have a significant prepatent period in the host, where they have moulted to adults but not yet started producing eggs or sperm; this stage is usually-should be conditioned by days post infection, with day 26 to approximately day 60 being the young adult in most systems - but note that the speed of development is different in different host genotypes. [wb:dr&mb]
all stages nematode [wbls:0000101]
all stages nematode
All developmental stages, including embryo, larva and adult stage. [wb:dr]
embryo nematode [wbls:0000102]
embryo nematode
postembryonic nematode [wbls:0000103]
postembryonic nematode
adult nematode [wbls:0000104]
adult nematode
The stage after an animal is fully-developed and reaches maturity. [wb:dr]
larva nematode [wbls:0000105]
larva nematode
L1 larva nematode [wbls:0000106]
L1 larva nematode
L2 larva nematode [wbls:0000107]
L2 larva nematode
L3 larva nematode [wbls:0000108]
L3 larva nematode
L4 larva nematode [wbls:0000109]
L4 larva nematode
sheathed microfilaria nematode [wbls:0000110]
sheathed microfilaria nematode
Microfilaria is the stage which develops from the egg and precedes the L1 stage. The larvae are surrounded by a membrane thought to be derived from the vitelline membrane. [wb:dr]
16-18 days post-L4 adult hermaphrodite Ce [wbls:0000111]
16-18 days post-L4 adult hermaphrodite Ce
At 20 Centigrade: 16-18 days after L4-adult molt. 18-21 days after first cleavage. [wb:dr]
part_of [obo:part_of]
xref [obo_vocabulary:xref]
xref
is_transitive [obo_vocabulary:is_transitive]
is_transitive
preceded_by [obo:preceded_by]
starts_at_end_of [obo:starts_at_end_of]