Caged_Fluorescent_Dye_Label
type: Class
subclass of: Photoactivatable Imaging Agent

Photoactivatable Imaging Agent
type: Class with Synonyms and Definitions
subclass of: Imaging Agent

Imaging Agent
type: Class with Synonyms and Definitions

Imaging Subject
type: Class with Synonyms and Definitions
comment: The living organism, or part of a living organism, on which an experimental or clinical research study is performed

Gene Knock-Out Model
type: Class
subclass of: Transgenic Model

Transgenic Model
type: Class with Synonyms and Definitions
subclass of: Model

Model
type: Class with Synonyms and Definitions
subclass of: In vivo subject

In vivo subject
type: Class with Synonyms and Definitions
subclass of: Imaging Subject

Tomography
type: Class
subclass of: Imaging Technique

Imaging Technique
type: Class with Synonyms and Definitions

Electron microscopy
type: Class
subclass of: Imaging Technique

Gadolinium_
type: Class with Synonyms and Definitions
subclass of: Magnetic resonance susceptibility

Magnetic resonance susceptibility
type: Class with Synonyms and Definitions
subclass of: Imaging Agent Source of Emitted Energy

Imaging Agent Source of Emitted Energy
type: Class with Synonyms and Definitions
subclass of: Imaging Agent

Gene Knock-In Model
type: Class
subclass of: Transgenic Model

Biological Target
type: Class with Synonyms and Definitions
comment: similar to process, there is normal vs. diseased/pathological, thus isPathological slot e.g. tumoral protease
definition: The part(s) of the biological subject that is visualized in the image and measured in order to create an imaging biomarker.

Class with Synonyms and Definitions
type: Class
subclass of: Class

Transient Gene Knock-Out Model
type: Class
subclass of: Transgenic Model

Treatment assessment
type: Class
subclass of: Clinical Endpoint

Clinical Endpoint
type: Class with Synonyms and Definitions
subclass of: Clinical Trial Endpoint
subclass of: Biomarker Use

Drug Development
type: Class with Synonyms and Definitions
subclass of: Research Use

Research Use
type: Class with Synonyms and Definitions
subclass of: Biomarker Use

Biomarker Use
type: Class with Synonyms and Definitions

Magnetic resonance angiography
type: Class
subclass of: Magnetic Resonance Imaging

Magnetic Resonance Imaging
type: Class with Synonyms and Definitions
subclass of: Magnetic resonance imaging

Magnetic resonance imaging
type: Class with Synonyms and Definitions
subclass of: qibo resource:arcb8a4b13
subclass of: qibo resource:arcb8a4b14
subclass of: qibo resource:arcb8a4b15
subclass of: qibo resource:arcb8a4b16
subclass of: Imaging Technique
subclass of: qibo resource:arcb8a4b17
subclass of: qibo resource:arcb8a4b18
subclass of: qibo resource:arcb8a4b19

qibo resource:arcb8a4b13
type: Restriction
on property: uses MRI pulse sequence
has value: Spin echo sequence

uses MRI pulse sequence
type: DatatypeProperty
domain: qibo resource:arcb8a4b222
type: FunctionalProperty
range: string

qibo resource:arcb8a4b14
type: Restriction
on property: uses MRI pulse sequence
has value: Echo planar sequence

qibo resource:arcb8a4b15
type: Restriction
has value: Diffusion pulse sequence
on property: uses MRI pulse sequence

qibo resource:arcb8a4b16
type: Restriction
on property: uses MRI pulse sequence
has value: Saturation recovery sequence

qibo resource:arcb8a4b17
type: Restriction
on property: uses MRI pulse sequence
has value: Gradient echo sequence

qibo resource:arcb8a4b18
type: Restriction
on property: uses MRI pulse sequence
has value: Spiral sequence

qibo resource:arcb8a4b19
type: Restriction
has value: Inversion recovery sequence
on property: uses MRI pulse sequence

Adenocarcinoma
type: Class with Synonyms and Definitions
subclass of: Carcinoma

Carcinoma
type: Class with Synonyms and Definitions
subclass of: Oncologic disease pathology

Oncologic disease pathology
type: Class with Synonyms and Definitions
subclass of: Disease

Disease
type: Class with Synonyms and Definitions
subclass of: Indicated Biology
comment: Note: these slots are not of the study of the biology, but of the disease itself, so may not apply here appropriately - use MESH terms

Indicated Biology
type: Class with Synonyms and Definitions

requires parameter
type: ObjectProperty
domain: qibo resource:arcb8a4b27

Post-processing Algorithm
type: Class with Synonyms and Definitions

is from source
type: ObjectProperty
domain: qibo resource:arcb8a4b30
type: FunctionalProperty

In vitro subject
type: Class with Synonyms and Definitions
definition: Living tissue in an artificial environment outside the organism for at least 24 hours or with some alteration of natural conditions
subclass of: Imaging Subject

Acquisition Device
type: Class with Synonyms and Definitions

Quantitative Imaging Biomarker
type: Class with Synonyms and Definitions
subclass of: Thing
subclass of: qibo resource:arcb8a4b33
subclass of: qibo resource:arcb8a4b34
subclass of: qibo resource:arcb8a4b35
comment: difference between parameter and biomarker_use is that parameter is a quantitative measurement, biomarker_use specifies funcitonal application, e.g. bioimarker: change in tumor diameter, applicaiton: disease monitoring (Tiffany);

qibo resource:arcb8a4b33
type: Restriction
on property: has temporality
has value: dynamic

has temporality
type: DatatypeProperty
type: FunctionalProperty
range: string
domain: qibo resource:arcb8a4b79

qibo resource:arcb8a4b34
type: Restriction
has value: single
on property: has temporality

qibo resource:arcb8a4b35
type: Restriction
on property: has temporality
has value: serial

is generated by
type: InverseFunctionalProperty
range: Acquisition Device
domain: qibo resource:arcb8a4b246
type: FunctionalProperty
type: ObjectProperty
inverse of: generates

is targetted by
type: ObjectProperty
comment: A biological target may be targetted by an exogenous material such as an imaging agent, or the target may itself be imageable, thus not requiring the use of an Imaging Agent.
type: FunctionalProperty

is affected by
type: ObjectProperty
comment: Can be null, if the subject was not treated in any way, such as a human subject receiving an MRI with no prior treatments, etc.
type: FunctionalProperty

requires preceding algorithm
type: ObjectProperty
domain: qibo resource:arcb8a4b36

is biomarker of
type: ObjectProperty
type: FunctionalProperty

results in parameter
type: ObjectProperty
domain: qibo resource:arcb8a4b39

models disease
type: ObjectProperty
domain: qibo resource:arcb8a4b42
range: Disease

Mouse
type: Class with Synonyms and Definitions
subclass of: Rodent Model

Rodent Model
type: Class with Synonyms and Definitions
comment: adapted NCI thesaurus
subclass of: Non-human mammalian organism

Non-human mammalian organism
type: Class with Synonyms and Definitions
subclass of: Organism

Organism
type: Class with Synonyms and Definitions
subclass of: In vivo subject

is a change in measurement
type: ObjectProperty
comment: When the measurement is a change in some other parameter, such as an increase in diameter.
type: FunctionalProperty
domain: qibo resource:arcb8a4b45

Measurement of Change
type: Class with Synonyms and Definitions
comment: Not sure if this is the correct term to use. It is meant to be able to identify a change in some other parameter, such as a "+24%" change [i.e. increase] in size, or a "-25%" change [i.e. decrease] in some rate. In some cases it is a change in some other measurement, which explains the slot, "is a change in measurement."
subclass of: Quantitative Imaging Biomarker

is measured relative to
type: ObjectProperty
domain: qibo resource:arcb8a4b48
type: FunctionalProperty

Locational Parameter
type: Class with Synonyms and Definitions
subclass of: Anatomical Measurement

Anatomical Measurement
type: Class with Synonyms and Definitions
subclass of: Quantitative Imaging Biomarker
comment: Still determining name; prior name was Anatomical Measurement

is derived from
type: ObjectProperty
type: FunctionalProperty

is indicated as being
type: ObjectProperty
type: FunctionalProperty

is a biomarker for
type: ObjectProperty
type: FunctionalProperty

is measurement of
type: ObjectProperty
type: FunctionalProperty
range: Indicated Biology
domain: Quantitative Imaging Biomarker
inverse of: is quantified by

is quantified by
type: InverseFunctionalProperty
range: Quantitative Imaging Biomarker
type: ObjectProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b240
inverse of: is measurement of

organ site
type: ObjectProperty
domain: qibo resource:arcb8a4b51
type: FunctionalProperty

targeting
type: ObjectProperty
type: FunctionalProperty

is applied to
type: ObjectProperty

affinity
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b54
range: string

sensitivity
type: DatatypeProperty
domain: qibo resource:arcb8a4b57
type: FunctionalProperty
range: float

specificity
type: DatatypeProperty
range: float
type: FunctionalProperty
domain: qibo resource:arcb8a4b60

MGI strain ID
type: DatatypeProperty
domain: qibo resource:arcb8a4b63
range: string
type: FunctionalProperty

targeted tissue
type: DatatypeProperty
domain: qibo resource:arcb8a4b66
type: FunctionalProperty
range: string

Induced gene expression
type: Class with Synonyms and Definitions
subclass of: Genetic engineering

Genetic engineering
type: Class with Synonyms and Definitions
subclass of: Biological Intervention

Biological Intervention
type: Class with Synonyms and Definitions
definition: Manipulation of the subject for biological interrogation, but not for imaging purposes. For imaging purposes are in imaging agent.

sectioning technique
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b69
type: FunctionalProperty

Transmission_Electron_Micrscope
type: Class with Synonyms and Definitions
subclass of: Electron Microscope
subclass of: qibo resource:arcb8a4b72
subclass of: qibo resource:arcb8a4b73
subclass of: qibo resource:arcb8a4b74

Electron Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

Microscope
type: Class with Synonyms and Definitions
subclass of: Acquisition Device

qibo resource:arcb8a4b72
type: Restriction
on property: sectioning technique
has value: freeze-fracturing

qibo resource:arcb8a4b73
type: Restriction
on property: sectioning technique
has value: slicing

qibo resource:arcb8a4b74
type: Restriction
has value: freeze-etching
on property: sectioning technique

has been treated with
type: DatatypeProperty
range: string
type: FunctionalProperty

is_pathological
type: DatatypeProperty
range: boolean
type: FunctionalProperty
domain: qibo resource:arcb8a4b75

Biological process
type: Class with Synonyms and Definitions
subclass of: Indicated Biology
comment: Import Biological Process class from Gene Ontology (highest level class), or from Biological Process class in NCI Thesaurus. We cannot just Gene ontology for biological process, because some processes are not due to genetic, e.g. macrophage infiltration, intraplaque hemorrhage

to_imaging_agent
type: DatatypeProperty
type: FunctionalProperty
range: string
comment: Imaging agent directly binds to the biological target, or the biological target is downstream to what imaging agent binds e.g. MRI with magnetic nanoparticles monitors downstream anti-angiogenic effects of mTOR inhibition

half life
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b82
range: string

Radionuclide
type: Class with Synonyms and Definitions
subclass of: qibo resource:arcb8a4b85
subclass of: qibo resource:arcb8a4b86
subclass of: Imaging Agent Source of Emitted Energy
subclass of: qibo resource:arcb8a4b87
subclass of: qibo resource:arcb8a4b88
comment: An atom with an unstable nucleus that will undergo radioactive decay emitting a gamma ray or a subatomic particle.

qibo resource:arcb8a4b85
type: Restriction
on property: Emitter
has value: Beta

Emitter
type: DatatypeProperty
domain: qibo resource:arcb8a4b159
type: FunctionalProperty
range: string

qibo resource:arcb8a4b86
type: Restriction
on property: Emitter
has value: Multiple radiation emitter

qibo resource:arcb8a4b87
type: Restriction
on property: Emitter
has value: Alpha

qibo resource:arcb8a4b88
type: Restriction
has value: Gamma
on property: Emitter

toxicity
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b89
range: string

name
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b92
range: string

Therapeutic intervention
type: Class with Synonyms and Definitions
comment: NCI thesaurus
subclass of: Biological Intervention

is endogenous
type: DatatypeProperty
range: boolean

specific_targeting
type: DatatypeProperty
range: boolean
type: FunctionalProperty

radioactivity
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b97
range: string

uses PET reconstruction algorithm
type: DatatypeProperty
type: FunctionalProperty
range: string
domain: qibo resource:arcb8a4b100

Positron Emission Tomography
type: Class with Synonyms and Definitions
subclass of: Radionuclide imaging
subclass of: qibo resource:arcb8a4b107
subclass of: qibo resource:arcb8a4b108
subclass of: qibo resource:arcb8a4b109

Radionuclide imaging
type: Class with Synonyms and Definitions
subclass of: Imaging Technique
subclass of: qibo resource:arcb8a4b103
subclass of: qibo resource:arcb8a4b104
subclass of: qibo resource:arcb8a4b105
subclass of: qibo resource:arcb8a4b106

qibo resource:arcb8a4b103
type: Restriction
on property: scintillator
has value: Thallium-activated sodium iodide (NaI(TI))

scintillator
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b177
type: FunctionalProperty

qibo resource:arcb8a4b104
type: Restriction
has value: Lutetium yttrium oxyorthosilicate (LYSO)
on property: scintillator

qibo resource:arcb8a4b105
type: Restriction
on property: scintillator
has value: Lutetium oxyorthosilicate (LSO)

qibo resource:arcb8a4b106
type: Restriction
has value: Bismuth germanate (BGO)
on property: scintillator

qibo resource:arcb8a4b107
type: Restriction
on property: uses PET reconstruction algorithm
has value: Attenuation-weighted OSEM (AWOSEM)

qibo resource:arcb8a4b108
type: Restriction
on property: uses PET reconstruction algorithm
has value: Fourier rebinning (FORE)

qibo resource:arcb8a4b109
type: Restriction
on property: uses PET reconstruction algorithm
has value: Ordered-subset expection maxmization (OSEM)

quantum_yield (QY)
type: DatatypeProperty
type: FunctionalProperty
range: float
domain: qibo resource:arcb8a4b110

Optical
type: Class with Synonyms and Definitions
subclass of: Imaging Agent Source of Emitted Energy
subclass of: qibo resource:arcb8a4b113

qibo resource:arcb8a4b113
type: Restriction
on property: optical_phenomenon
has value: photochromism (blinking)

optical_phenomenon
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b203
range: string

excitation_spectrum
type: DatatypeProperty
range: float
domain: qibo resource:arcb8a4b114
type: FunctionalProperty

binding affinity (Ki)
type: DatatypeProperty
type: FunctionalProperty
range: string

genetic background
type: DatatypeProperty
comment: mainly instances from the Mouse class
range: string
type: FunctionalProperty
domain: qibo resource:arcb8a4b117

Genetically engineered mutant mouse
type: Class with Synonyms and Definitions
subclass of: Mutant strain

Mutant strain
type: Class with Synonyms and Definitions
subclass of: Mouse

is of dimension
type: DatatypeProperty
type: FunctionalProperty
range: string
domain: qibo resource:arcb8a4b120

gene knockin or knockout
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b123
type: FunctionalProperty

emission_wavelength
type: DatatypeProperty
domain: qibo resource:arcb8a4b126
range: float
type: FunctionalProperty

phenotype/symptom
type: DatatypeProperty
range: string
type: FunctionalProperty
domain: qibo resource:arcb8a4b129

immunodeficiency_type
type: DatatypeProperty
domain: qibo resource:arcb8a4b132
type: FunctionalProperty
range: string

Xenograft
type: Class with Synonyms and Definitions
subclass of: Surgical procedure

Surgical procedure
type: Class with Synonyms and Definitions
subclass of: Biological Intervention

size
type: DatatypeProperty
type: FunctionalProperty
range: string
domain: qibo resource:arcb8a4b135

expression_is_observed
type: DatatypeProperty
type: FunctionalProperty
range: boolean
domain: qibo resource:arcb8a4b138

Stomach
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Multicellular/Organ-level Target
type: Class with Synonyms and Definitions
subclass of: Biological Target

signal_amplication_strategy
type: DatatypeProperty
type: FunctionalProperty
range: string

requires input
type: DatatypeProperty
range: string
type: FunctionalProperty

definition
type: DatatypeProperty
domain: qibo resource:arcb8a4b141
range: string
type: FunctionalProperty

biodistribution
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b144
range: string

lipophilic
type: DatatypeProperty
domain: qibo resource:arcb8a4b147
range: boolean
type: FunctionalProperty

intravascular half-life
type: DatatypeProperty
range: string
type: FunctionalProperty

excitation_coefficient (EC)
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b150
range: float

energy
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b153

image_type
type: DatatypeProperty
type: FunctionalProperty
range: string

is_abnormal
type: DatatypeProperty
range: boolean
domain: qibo resource:arcb8a4b156
comment: Target is not expressed in normal cells, e.g. disialoganglioside in micad. These targets may not normally be found in GO.
type: FunctionalProperty

Anatomical component
type: Class with Synonyms and Definitions
subclass of: Non-specific
comment: This class - should be removed Either import from corresponding FMA subclasses OR from NCI Thesaurus "Anatomic Structure, System or Substance" class, which includes microanatomic structures.

Non-specific
type: Class with Synonyms and Definitions
subclass of: Biological Target

physical_phenomenon
type: DatatypeProperty
type: FunctionalProperty
range: string
domain: qibo resource:arcb8a4b162

optical_property
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b165
type: FunctionalProperty

probe activity
type: DatatypeProperty
type: FunctionalProperty
range: string

deposition method
type: DatatypeProperty
range: string
type: FunctionalProperty

is genetic
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b168
range: boolean

has unit
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b171
range: string

tracer half life
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b174
range: float

Radioisotope
type: Class with Synonyms and Definitions
comment: these are radioactive atoms ... mainly used for SPECT/PET
subclass of: Imaging Agent

strain name
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b180
range: string

super resolution technique
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b183
type: FunctionalProperty

Super Resolution Microscope
type: Class with Synonyms and Definitions
subclass of: qibo resource:arcb8a4b186
subclass of: qibo resource:arcb8a4b187
subclass of: qibo resource:arcb8a4b188
subclass of: qibo resource:arcb8a4b189
subclass of: qibo resource:arcb8a4b190
subclass of: qibo resource:arcb8a4b191
subclass of: qibo resource:arcb8a4b192
subclass of: qibo resource:arcb8a4b193
subclass of: Optical Microscope
subclass of: qibo resource:arcb8a4b194
subclass of: qibo resource:arcb8a4b195
subclass of: qibo resource:arcb8a4b196

qibo resource:arcb8a4b186
type: Restriction
has value: 4Pi
on property: super resolution technique

qibo resource:arcb8a4b187
type: Restriction
on property: super resolution technique
has value: 2CLM

qibo resource:arcb8a4b188
type: Restriction
on property: super resolution technique
has value: PALM

qibo resource:arcb8a4b189
type: Restriction
has value: SSIM
on property: super resolution technique

qibo resource:arcb8a4b190
type: Restriction
has value: SIM
on property: super resolution technique

qibo resource:arcb8a4b191
type: Restriction
has value: GSD
on property: super resolution technique

qibo resource:arcb8a4b192
type: Restriction
has value: SPEM
on property: super resolution technique

qibo resource:arcb8a4b193
type: Restriction
on property: super resolution technique
has value: STED

Optical Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

qibo resource:arcb8a4b194
type: Restriction
on property: super resolution technique
has value: Vertico-SMI

qibo resource:arcb8a4b195
type: Restriction
on property: super resolution technique
has value: STORM

qibo resource:arcb8a4b196
type: Restriction
on property: super resolution technique
has value: RESOLOFT

KB_396445_Class6
type: DatatypeProperty
range: string
type: FunctionalProperty

excretion
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b197
type: FunctionalProperty

uses antibody
type: DatatypeProperty
range: string
type: FunctionalProperty

Genetic background
type: DatatypeProperty
comment: which mouse strain this mutant mouse derived from. genetic background may be instances of Mouse
type: FunctionalProperty
range: string

mutant gene
type: DatatypeProperty
domain: qibo resource:arcb8a4b200
range: string
type: FunctionalProperty

tissue specific promoter
type: DatatypeProperty
type: FunctionalProperty
range: string
domain: qibo resource:arcb8a4b206

T1_shortening
type: DatatypeProperty
range: boolean
domain: qibo resource:arcb8a4b209
type: FunctionalProperty

Manganese
type: Class with Synonyms and Definitions
subclass of: Magnetic resonance susceptibility

isAutomated
type: DatatypeProperty
range: boolean
domain: qibo resource:arcb8a4b213
type: FunctionalProperty

Image segmentation algorithm
type: Class with Synonyms and Definitions
subclass of: Image Processing Technique

Image Processing Technique
type: Class with Synonyms and Definitions
subclass of: Post-processing Algorithm

is of species
type: DatatypeProperty
type: FunctionalProperty
range: string

T2*-weighted
type: DatatypeProperty
type: FunctionalProperty
range: string
domain: qibo resource:arcb8a4b216

Iron
type: Class with Synonyms and Definitions
subclass of: Magnetic resonance susceptibility

stokes_shfit
type: DatatypeProperty
range: string
domain: qibo resource:arcb8a4b219
type: FunctionalProperty

is set of objects
type: DatatypeProperty
type: FunctionalProperty
range: boolean

location
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b225
range: string

dose
type: DatatypeProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b228
range: string

route of elimination
type: DatatypeProperty
range: string
type: FunctionalProperty

molecular weight
type: DatatypeProperty
range: float
type: FunctionalProperty

light_source
type: DatatypeProperty
range: string
type: FunctionalProperty

treatment
type: DatatypeProperty
domain: qibo resource:arcb8a4b231
type: FunctionalProperty
range: string

strain type
type: DatatypeProperty
domain: qibo resource:arcb8a4b234
type: FunctionalProperty
range: string

emission_spectrum
type: DatatypeProperty
domain: qibo resource:arcb8a4b237
range: float
type: FunctionalProperty

is measured by
type: InverseFunctionalProperty
inverse of: measures
type: ObjectProperty
type: FunctionalProperty
range: Quantitative Imaging Biomarker
domain: Biological Target

disease_treated
type: InverseFunctionalProperty
domain: Biological Intervention
type: ObjectProperty
type: FunctionalProperty
inverse of: can be treated
range: Disease

participates in
type: InverseFunctionalProperty
domain: qibo resource:arcb8a4b243
type: ObjectProperty
type: FunctionalProperty
range: Indicated Biology
inverse of: involves

has undergone
type: InverseFunctionalProperty
range: Biological Intervention
domain: Imaging Subject
type: ObjectProperty
type: FunctionalProperty
inverse of: is performed on

is used for
type: InverseFunctionalProperty
domain: Quantitative Imaging Biomarker
range: Biomarker Use
inverse of: uses
type: FunctionalProperty
type: ObjectProperty

is imaged with
type: InverseFunctionalProperty
inverse of: images
range: Acquisition Device
comment: Only the biological subject is imaged. We do not consider the Target or the Agent to be imaged, since they are within the subject, which is being imaged.
type: ObjectProperty
type: FunctionalProperty
domain: qibo resource:arcb8a4b249

Carbon Nanotube
type: Class with Synonyms and Definitions
subclass of: Nanoprobe
comment: as a carrier

Nanoprobe
type: Class with Synonyms and Definitions
subclass of: Imaging Agent

Selectin
type: Class with Synonyms and Definitions
subclass of: Cell adhesion protein

Cell adhesion protein
type: Class with Synonyms and Definitions
subclass of: Membrane receptor
comment: vascular cell adhesion molecule 1

Membrane receptor
type: Class with Synonyms and Definitions
subclass of: Cell membrane protein

Cell membrane protein
type: Class with Synonyms and Definitions
subclass of: Cell surface Protein

Cell surface Protein
type: Class with Synonyms and Definitions
subclass of: Protein__

Protein__
type: Class with Synonyms and Definitions
subclass of: Molecular Target

Molecular Target
type: Class with Synonyms and Definitions
subclass of: Biological Target

Fab
type: Class with Synonyms and Definitions
subclass of: Antibody Fragment

Antibody Fragment
type: Class with Synonyms and Definitions
subclass of: Antibody__

Antibody__
type: Class with Synonyms and Definitions
subclass of: Proteins and Polypeptide

Proteins and Polypeptide
type: Class with Synonyms and Definitions
subclass of: Biological macromolecule

Biological macromolecule
type: Class with Synonyms and Definitions
subclass of: Imaging Agent
definition: is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. -- Ontology for Drug Discovery Investigations

Feeding difficulty
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Gastrointestinal disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Systemic disease pathology
type: Class with Synonyms and Definitions
subclass of: Disease

Left Neck
type: Class with Synonyms and Definitions
subclass of: Neck

Neck
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Fatty liver
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Coagulation
type: Class with Synonyms and Definitions
subclass of: Multicellular process

Multicellular process
type: Class with Synonyms and Definitions
subclass of: Biological process

SECARS
type: Class with Synonyms and Definitions
subclass of: Raman Scattering Spectroscopy

Raman Scattering Spectroscopy
type: Class with Synonyms and Definitions
subclass of: Optical imaging

Optical imaging
type: Class with Synonyms and Definitions
subclass of: Imaging Technique

Time of flight (TOF)
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Mouse Model of Disease
type: Class with Synonyms and Definitions
subclass of: Mouse

Time activity curve (TAC)
type: Class with Synonyms and Definitions
subclass of: Kinetic biomarker

Kinetic biomarker
type: Class with Synonyms and Definitions
subclass of: Functional Measurement

Functional Measurement
type: Class with Synonyms and Definitions
subclass of: Quantitative Imaging Biomarker

KB 827440 Class16
type: Cls(:PAL-CONSTRAINT)

Thyroid disease
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

Endocrine disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Simulated Emission Depletion Microscope
type: Class with Synonyms and Definitions
subclass of: Super Resolution Microscope

Kidney
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

F6F
type: Class with Synonyms and Definitions
subclass of: Growth factor

Growth factor
type: Class with Synonyms and Definitions
subclass of: Extracellular signaling molecule

Extracellular signaling molecule
type: Class with Synonyms and Definitions
subclass of: Protein__

KB 579095 Class10
type: Wild strain
strain name: B6.129

Lipid__
type: Class with Synonyms and Definitions
subclass of: Microbubble shell

Microbubble shell
type: Class with Synonyms and Definitions
subclass of: Microbubble

Microbubble
type: Class with Synonyms and Definitions
subclass of: Ultrasonic

Ultrasonic
type: Class with Synonyms and Definitions
subclass of: Imaging Agent Source of Emitted Energy

Planar Nuclear Medicine Imaging
type: Class with Synonyms and Definitions
subclass of: Single Photon Imaging

Single Photon Imaging
type: Class with Synonyms and Definitions
comment: RadLex
subclass of: Radionuclide imaging

Contour identification
type: Class with Synonyms and Definitions
subclass of: Image segmentation algorithm

Zebrafish
type: Class with Synonyms and Definitions
subclass of: Non-mammalian organism

Non-mammalian organism
type: Class with Synonyms and Definitions
subclass of: Organism

Radiolabeled analog
type: Class with Synonyms and Definitions
subclass of: Radionuclide

Diabody
type: Class with Synonyms and Definitions
subclass of: Antibody Fragment

Hypotension
type: Class with Synonyms and Definitions
subclass of: Vascular disease

Vascular disease
type: Class with Synonyms and Definitions
subclass of: Cardiovascular disease

Cardiovascular disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Light sheet-based fluorescence microscopy
type: Class with Synonyms and Definitions
comment: Is this used for whole animal imaging????
subclass of: Fluorescence imaging

Fluorescence imaging
type: Class with Synonyms and Definitions
subclass of: Optical imaging

Viral infectious disease
type: Class with Synonyms and Definitions
subclass of: Infectious disease pathology

Infectious disease pathology
type: Class with Synonyms and Definitions
subclass of: Disease

Diarrhea
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Delivery
type: Class with Synonyms and Definitions
subclass of: Preclinical

Membrane transport protein
type: Class with Synonyms and Definitions
subclass of: Membrane receptor

Elastin
type: Class with Synonyms and Definitions
subclass of: Fibrous protein

Fibrous protein
type: Class with Synonyms and Definitions
subclass of: Extracellular matrix Protein

Extracellular matrix Protein
type: Class with Synonyms and Definitions
subclass of: Protein__

Surface_Area
type: Class with Synonyms and Definitions
subclass of: Size_Parameter

Size_Parameter
type: Class with Synonyms and Definitions
subclass of: Morphological Parameter

Morphological Parameter
type: Class with Synonyms and Definitions
comment: e.g. columnar
subclass of: Anatomical Measurement

Micro_Computed_Tomography
type: Class with Synonyms and Definitions
subclass of: Tomography

Neurotransmitter
type: Class with Synonyms and Definitions
subclass of: Extracellular signaling molecule

Perfusion MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Iodine binding receptor
type: Class with Synonyms and Definitions
subclass of: Membrane receptor

Intestine
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Ultrasmall Superparamagnetic Iron Oxide Nanoparticle
type: Class with Synonyms and Definitions
comment: USPIO is composed of iron particles of ~4–6 nm diameters and the hydrodynamic diameter is ~20–40 nm.
subclass of: Superparamagnetic Iron Oxide Nanoparticle

Superparamagnetic Iron Oxide Nanoparticle
type: Class with Synonyms and Definitions
subclass of: Nanoprobe

Wide field fluorescent microscope
type: Class with Synonyms and Definitions
subclass of: Optical Microscope

Deconvolution algorithm
type: Class with Synonyms and Definitions
subclass of: Image Processing Technique

Macrophage infiltration
type: Class with Synonyms and Definitions
subclass of: Infiltration

Infiltration
type: Class with Synonyms and Definitions
subclass of: Multicellular process

Raman-tagged
type: Class with Synonyms and Definitions
subclass of: Optical

Human subject
type: Class with Synonyms and Definitions
subclass of: Organism

Affine registration algorithm
type: Class with Synonyms and Definitions
subclass of: Image registration algorithm

Image registration algorithm
type: Class with Synonyms and Definitions
subclass of: Image Processing Technique
comment: An algorithm that geometrically aligns two images so that corresponding voxels/pixels can be superimposed on each other

Image thresholding algorithm
type: Class with Synonyms and Definitions
subclass of: Image Processing Technique

Chemically induced mutant mouse
type: Class with Synonyms and Definitions
subclass of: Mutant strain

Chicken
type: Class with Synonyms and Definitions
subclass of: Non-mammalian organism

KB 452273 Class0
type: Transgenic model
strain name: LAP-tTA/tet-off-MYC mouse

Computed Radiography
type: Class with Synonyms and Definitions
subclass of: X-ray

X-ray
type: Class with Synonyms and Definitions
subclass of: X-ray imaging

X-ray imaging
type: Class with Synonyms and Definitions
subclass of: Imaging Technique

Hypothalamus
type: Class with Synonyms and Definitions
subclass of: Brain

Brain
type: Class with Synonyms and Definitions
comment: Can be used to study biodistribution
subclass of: Multicellular/Organ-level Target

Gamma Camera
type: Class with Synonyms and Definitions
subclass of: Acquisition Device

Multiple tracer PET
type: Class with Synonyms and Definitions
subclass of: Positron Emission Tomography

Cytokine
type: Class with Synonyms and Definitions
subclass of: Extracellular signaling molecule

Genetically Manipulated Fusion Protein123
type: Class with Synonyms and Definitions
subclass of: Immunofluorescent Label

Immunofluorescent Label
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging agent

Fluorescence imaging agent
type: Class with Synonyms and Definitions
subclass of: Optical

Cross-linked Iron Oxide Nanoparticle
type: Class with Synonyms and Definitions
subclass of: Superparamagnetic Iron Oxide Nanoparticle

Apoptosis
type: Class with Synonyms and Definitions
subclass of: Multicellular process

Germ cell tumor
type: Class with Synonyms and Definitions
subclass of: Oncologic disease pathology

Microvascular permeability
type: Class with Synonyms and Definitions
subclass of: Permeability biomarker

Permeability biomarker
type: Class with Synonyms and Definitions
subclass of: Kinetic biomarker

Syrian Hamster
type: Class with Synonyms and Definitions
subclass of: Hamster

Hamster
type: Class with Synonyms and Definitions
subclass of: Non-human mammalian organism

Fluorescence reflectance imaging
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging

Image Reconstruction Algorithm
type: Class with Synonyms and Definitions
subclass of: Image Visualization Algorithm

Image Visualization Algorithm
type: Class with Synonyms and Definitions
subclass of: Post-processing Algorithm

Cytosine deaminase
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Intracellular protein
type: Class with Synonyms and Definitions
subclass of: Protein__

CARS
type: Class with Synonyms and Definitions
subclass of: Raman Scattering Spectroscopy

A mode
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

Ultrasound imaging
type: Class with Synonyms and Definitions
subclass of: Imaging Technique

Tube current modulated CT
type: Class with Synonyms and Definitions
subclass of: Computed Tomography

Computed Tomography
type: Class with Synonyms and Definitions
subclass of: X-ray imaging

Photoacoustic imaging
type: Class with Synonyms and Definitions
subclass of: Imaging Technique

KB 452273 Class2
type: Wild strain
strain name: BALB/c strain

Cell trafficking
type: Class with Synonyms and Definitions
subclass of: Cellular process

Cellular process
type: Class with Synonyms and Definitions
subclass of: Biological process

Cellular Localization
type: Class with Synonyms and Definitions
subclass of: Biology Investigation

Biology Investigation
type: Class with Synonyms and Definitions
subclass of: Research Use

Arrhthmia
type: Class with Synonyms and Definitions
subclass of: Cardiovascular disease

Apoptotic cell
type: Class with Synonyms and Definitions
subclass of: Cell under some process

Cell under some process
type: Class with Synonyms and Definitions
subclass of: Cellular Target

Cellular Target
type: Class with Synonyms and Definitions
subclass of: Biological Target

Pharmacokinetic parameter
type: Class with Synonyms and Definitions
subclass of: Kinetic biomarker

Diameter
type: Class with Synonyms and Definitions
subclass of: Size_Parameter

KB 452273 Class3
type: Wild strain
strain name: BALB/cByJ
models disease: Immunologic disease

Immunologic disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Congenic strain
type: Class with Synonyms and Definitions
subclass of: Mouse

Transplant rejection
type: Class with Synonyms and Definitions
subclass of: Disease

Displacement
type: Class with Synonyms and Definitions
subclass of: Deformation Parameter

Deformation Parameter
type: Class with Synonyms and Definitions
subclass of: Morphological Parameter

Glycosaminoglycan
type: Class with Synonyms and Definitions
subclass of: Polysaccharide

Polysaccharide
type: Class with Synonyms and Definitions
subclass of: Carbohydrate_

Carbohydrate_
type: Class with Synonyms and Definitions
subclass of: Biological macromolecule

Retinal disease
type: Class with Synonyms and Definitions
subclass of: Ophthalmologic disease

Ophthalmologic disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Sarcoma
type: Class with Synonyms and Definitions
subclass of: Oncologic disease pathology

Lipid Microbubble
type: Class with Synonyms and Definitions
subclass of: Lipid

Lipid
type: Class with Synonyms and Definitions
subclass of: Biological macromolecule

Cerebellum
type: Class with Synonyms and Definitions
subclass of: Brain

Minibody
type: Class with Synonyms and Definitions
subclass of: Antibody__

Creatinine kinase
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Scatter correction algorithm
type: Class with Synonyms and Definitions
subclass of: Noise correction algorithm

Noise correction algorithm
type: Class with Synonyms and Definitions
subclass of: Image Processing Technique

Iodine
type: Class with Synonyms and Definitions
subclass of: X-ray attenuator

X-ray attenuator
type: Class with Synonyms and Definitions
subclass of: Imaging Agent Source of Emitted Energy

KB 788804 Class29
type: Anticancer therapy
name: Bortezomib

Respiratory motion correction algorithm
type: Class with Synonyms and Definitions
subclass of: Motion correction algorithm

Motion correction algorithm
type: Class with Synonyms and Definitions
subclass of: Noise correction algorithm

Interferon induced gene expression
type: Class with Synonyms and Definitions
subclass of: Induced gene expression

KB 452273 Class6
type: Xenograft
immunodeficiency_type: athymic nude mouse

Monoclonal antibody
type: Class with Synonyms and Definitions
subclass of: Anticancer therapy

Anticancer therapy
type: Class with Synonyms and Definitions
subclass of: Therapeutic intervention
comment: NCI thesaurus

Hydrolase
type: Class with Synonyms and Definitions
subclass of: Enzyme

Enzyme
type: Class with Synonyms and Definitions
subclass of: Molecular Target

Cataract
type: Class with Synonyms and Definitions
subclass of: Ophthalmologic disease

Metastasis
type: Class with Synonyms and Definitions
subclass of: Multicellular process

KB 788804 Class28
type: Xenograft
immunodeficiency_type: SCID mouse

Tetramer
type: Class with Synonyms and Definitions
subclass of: Nanoprobe

Digital Radiography/Direct Radiography
type: Class with Synonyms and Definitions
subclass of: X-ray

Cortex
type: Class with Synonyms and Definitions
subclass of: Brain

KB 452273 Class16
type: Wild strain
strain name: FVB/NJ

Hyperhidrosis
type: Class with Synonyms and Definitions
subclass of: Dermatologic disease

Dermatologic disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Fluorine-18
type: Class with Synonyms and Definitions
subclass of: Radioisotope

Lyase
type: Class with Synonyms and Definitions
subclass of: Enzyme

Hormone
type: Class with Synonyms and Definitions
subclass of: Extracellular signaling molecule

Ultrasonic_Force Microscope
type: Class with Synonyms and Definitions
subclass of: Acoustic Microscope

Acoustic Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

Metabolic disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

KB 129148 Class13
type: Targeted Mutant Mouse
strain name: B6.129-Kras
mutant gene: Kras
genetic background: B6.129
gene knockin or knockout: Gene Knockout

Photoactivatable fluorescent protein
type: Class with Synonyms and Definitions
subclass of: Optical highlighter

Optical highlighter
type: Class with Synonyms and Definitions
subclass of: Fluorescent protein

Fluorescent protein
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging agent

ANSOM
type: Class with Synonyms and Definitions
subclass of: Near-field Probe Microscope

Near-field Probe Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

Second messenger
type: Class with Synonyms and Definitions
subclass of: Intracellular signaling molecule

Intracellular signaling molecule
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Amount
type: Class with Synonyms and Definitions
subclass of: Quantitative Imaging Biomarker
comment: most likely molecular e.g. macrophage content, integrin expression

Electron Beam CT (EBCT)
type: Class with Synonyms and Definitions
subclass of: Computed Tomography

KB 788804 Class27
type: Rat subject
name: Sprague Dawley rat

Ataxia
type: Class with Synonyms and Definitions
subclass of: Neurologic disease

Neurologic disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Xenograft Model
type: Class with Synonyms and Definitions
subclass of: Model
comment: NCI thesaurus

scFv
type: Class with Synonyms and Definitions
subclass of: Antibody Fragment

Transcription factor
type: Class with Synonyms and Definitions
subclass of: Intracellular signaling molecule

Pancreas
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Pharmacokinetic profile
type: Class with Synonyms and Definitions
subclass of: Preclinical

Predicting response to therapy
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

Positive Change
type: Class with Synonyms and Definitions
subclass of: Measurement of Change

Intracranial hemorrhage
type: Class with Synonyms and Definitions
subclass of: Neurologic disease

Stereoscopic
type: Class with Synonyms and Definitions
subclass of: Light Microscope

Light Microscope
type: Class with Synonyms and Definitions
subclass of: Optical Microscope

Scanning Tunneling Microscope123
type: Class with Synonyms and Definitions
subclass of: Electron Microscope

Adrenal gland disease
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

KB 788804 Class25
type: Non-human mammalian organism
name: New Zealand white rabbit

KB 788804 Class22
type: Cell line
name: KB-G2 human epidermoid carcinoma cell

Photoswitchable fluorescent protein
type: Class with Synonyms and Definitions
subclass of: Photoactivatable Imaging Agent

Budding Yeast
type: Class with Synonyms and Definitions
subclass of: Yeast

Yeast
type: Class with Synonyms and Definitions
subclass of: Non-mammalian organism

KB 788804 Class23
type: Xenograft
immunodeficiency_type: athymic nude mouse

Collagen
type: Class with Synonyms and Definitions
subclass of: Fibrous protein

Perfluorocarbon emulsion
type: Class with Synonyms and Definitions
subclass of: Ultrasonic

Dynamic PET
type: Class with Synonyms and Definitions
subclass of: Positron Emission Tomography

Tumor
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Bioluminescence
type: Class with Synonyms and Definitions
subclass of: Optical

Ultra-small superparamagnetic iron oxide particle (USPIO)
type: Class with Synonyms and Definitions
subclass of: Iron nanoparticle

Iron nanoparticle
type: Class with Synonyms and Definitions
subclass of: Iron

Carbon-11
type: Class with Synonyms and Definitions
subclass of: Radioisotope

Thymidine kinase
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

KB 788804 Class20
type: Cell line
name: A431 human epidermoid carcinoma cells

Reflection_Interference_Contrast_(RICM)
type: Class with Synonyms and Definitions
subclass of: Light Microscope

X-ray_Microscope
type: Class with Synonyms and Definitions
subclass of: X-ray imaging

Metallothionein promoter induced gene expression
type: Class with Synonyms and Definitions
subclass of: Induced gene expression

Functional MRI (fMRI)
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

C. elegans
type: Class with Synonyms and Definitions
subclass of: Non-mammalian organism

Mammography
type: Class with Synonyms and Definitions
subclass of: X-ray

KB 788804 Class21
type: Cell line
name: U87MG human glioma cell line

Activation
type: Class with Synonyms and Definitions
subclass of: Functional Measurement

Photoconvertible fluorescent protein
type: Class with Synonyms and Definitions
subclass of: Optical highlighter

Bright-field
type: Class with Synonyms and Definitions
subclass of: Light Microscope

Albumin_
type: Class with Synonyms and Definitions
subclass of: Microbubble shell

Stimulated_Raman_Scattering
type: Class with Synonyms and Definitions
subclass of: Raman Scattering Spectroscopy

RNA interference
type: Class with Synonyms and Definitions
subclass of: Temporo-spatially modified gene expression

Temporo-spatially modified gene expression
type: Class with Synonyms and Definitions
subclass of: Induced gene expression

Stem Cell
type: Class with Synonyms and Definitions
subclass of: Cell

Cell
type: Class with Synonyms and Definitions
subclass of: Imaging Agent

Immunoglobulin superfamily protein
type: Class with Synonyms and Definitions
subclass of: Cell adhesion protein

Radiolabeled antibody
type: Class with Synonyms and Definitions
subclass of: Radionuclide

Barium_
type: Class with Synonyms and Definitions
subclass of: Atom

Atom
type: Class with Synonyms and Definitions
comment: mainly used in MRI
subclass of: Imaging Agent

Pancreatitis
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Pathway-Level Target
type: Class with Synonyms and Definitions
subclass of: Biological Target

Antibody mimetic
type: Class with Synonyms and Definitions
subclass of: Chemically Synthetic Molecule
definition: organic compounds that, like antibodies, can specifically bind antigens, but that are not structurally related to antibodies. They are usually artificial peptides or proteins with a molar mass of about 3 to 20 kDa. --Wikipedia

Chemically Synthetic Molecule
type: Class with Synonyms and Definitions
comment: molecules that may not endogenously produced
subclass of: Small Molecule

Small Molecule
type: Class with Synonyms and Definitions
definition: A molecule that is a monomer or short oligomer that is not determined by a genome sequence. - adapted from NCI thesaurus
subclass of: Imaging Agent

Disease staging
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

DNA
type: Class with Synonyms and Definitions
subclass of: Molecular Target

Standard Superparamagnetic Iron Oxide Nanoparticle
type: Class with Synonyms and Definitions
subclass of: Superparamagnetic Iron Oxide Nanoparticle

Total Internal Reflection Fluorescence (TIRF)
type: Class with Synonyms and Definitions
subclass of: Laser_based_Optical_Microscope

Laser_based_Optical_Microscope
type: Class with Synonyms and Definitions
subclass of: Optical Microscope

Receptor, Cannabinoid
type: Class with Synonyms and Definitions
subclass of: Membrane receptor

Skin
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Carrier protein
type: Class with Synonyms and Definitions
subclass of: Cell membrane protein

Atherosclerosis
type: Class with Synonyms and Definitions
subclass of: Cardiovascular disease

Urogenital disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Oxidoreductase
type: Class with Synonyms and Definitions
subclass of: Enzyme

Inbred strain
type: Class with Synonyms and Definitions
subclass of: Mouse

Attenuation correction algorithm
type: Class with Synonyms and Definitions
subclass of: Noise correction algorithm

Color vision defect
type: Class with Synonyms and Definitions
subclass of: Ophthalmologic disease

Blepharoptosis
type: Class with Synonyms and Definitions
subclass of: Ophthalmologic disease

KB 589289 Class0
type: Cls(:PAL-CONSTRAINT)

Renal disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Cadherin
type: Class with Synonyms and Definitions
subclass of: Cell adhesion protein

Atomic de Broglie
type: Class with Synonyms and Definitions
subclass of: Atom Optic Microscope

Atom Optic Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

Pathological target
type: Class with Synonyms and Definitions
subclass of: Protein__

Roundness
type: Class with Synonyms and Definitions
subclass of: Shape_Parameter

Shape_Parameter
type: Class with Synonyms and Definitions
subclass of: Morphological Parameter

Widefield fluorescence microscopy
type: Class with Synonyms and Definitions
comment: Is this used for whole animal imaging????
subclass of: Fluorescence imaging

Pituitary disease
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

T1-weighted MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Escherichia coli
type: Class with Synonyms and Definitions
subclass of: Bacterium cell

Bacterium cell
type: Class with Synonyms and Definitions
subclass of: Cell
comment: I put bacterium under cell because it's single cell organism. Since the identity of the cell is not important, but debatable...

MMTV-LTR promoter induced gene expression
type: Class with Synonyms and Definitions
subclass of: Induced gene expression

Rotation
type: Class with Synonyms and Definitions
subclass of: Deformation Parameter

Synthetic fluorescent dye
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging agent

Cathepsin
type: Class with Synonyms and Definitions
subclass of: Protease

Protease
type: Class with Synonyms and Definitions
subclass of: Enzyme

20-OH ecdysone induced gene expression
type: Class with Synonyms and Definitions
subclass of: Induced gene expression

Bone
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Immunodeficient xenograft rat subject
type: Class with Synonyms and Definitions
subclass of: Rat subject

Rat subject
type: Class with Synonyms and Definitions
subclass of: Rodent Model

Chemical
type: Class with Synonyms and Definitions
subclass of: Small Molecule

Volume
type: Class with Synonyms and Definitions
subclass of: Size_Parameter

Cerebral blood flow
type: Class with Synonyms and Definitions
subclass of: Perfusion biomarker

Perfusion biomarker
type: Class with Synonyms and Definitions
subclass of: Kinetic biomarker

Disease diagnostic
type: Class with Synonyms and Definitions
subclass of: Disease Characterization

Disease Characterization
type: Class with Synonyms and Definitions
subclass of: Biomarker Use

Dorsal Skinfold Window Chamber Model
type: Class with Synonyms and Definitions
subclass of: Model
comment: NCI thesaurus

Mouse Xenograft Model
type: Class with Synonyms and Definitions
subclass of: Mouse

Quantitation Algorithm
type: Class with Synonyms and Definitions
subclass of: Image Analysis Technique

Image Analysis Technique
type: Class with Synonyms and Definitions
subclass of: Post-processing Algorithm

Non-rigid registration algorithm
type: Class with Synonyms and Definitions
subclass of: Image registration algorithm

KB 129148 Class15
type: Targeted Mutant Mouse
gene knockin or knockout: Gene Knockout
genetic background: B6.129S6
strain name: B6.129S6-Nf1
mutant gene: Nf1 (Neurofibromatosis 1)

Coordinate_Location
type: Class with Synonyms and Definitions
subclass of: Locational Parameter
comment: e.g. apical, ventral

Film Radiography
type: Class with Synonyms and Definitions
subclass of: X-ray

Smoothness
type: Class with Synonyms and Definitions
subclass of: Texture_Parameter

Texture_Parameter
type: Class with Synonyms and Definitions
subclass of: Morphological Parameter

Pathologic nystagmus
type: Class with Synonyms and Definitions
subclass of: Ophthalmologic disease

KB 579095 Class9
type: Wild strain
strain name: C57BL/6

Raman
type: Class with Synonyms and Definitions
subclass of: Atom

Bioluminescence imaging
type: Class with Synonyms and Definitions
subclass of: Optical imaging

Image Intensifier Fluoroscopy
type: Class with Synonyms and Definitions
subclass of: Fluoroscopy

Fluoroscopy
type: Class with Synonyms and Definitions
subclass of: X-ray imaging

Myocardial infarction
type: Class with Synonyms and Definitions
subclass of: Cardiovascular disease

Translation
type: Class with Synonyms and Definitions
subclass of: Subcellular process

Subcellular process
type: Class with Synonyms and Definitions
subclass of: Biological process

Curvature
type: Class with Synonyms and Definitions
subclass of: Shape_Parameter

Endoscope
type: Class with Synonyms and Definitions
subclass of: Optical imaging

Dual Source CT
type: Class with Synonyms and Definitions
subclass of: Computed Tomography

Optical coherence tomography
type: Class with Synonyms and Definitions
subclass of: Whole Animal Optical Imaging

Whole Animal Optical Imaging
type: Class with Synonyms and Definitions
subclass of: Optical imaging

Single Photon Emission Computed Tomography
type: Class with Synonyms and Definitions
subclass of: Single Photon Imaging

Gastroenteritis
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Length
type: Class with Synonyms and Definitions
subclass of: Size_Parameter

Lymphocyte homing receptor
type: Class with Synonyms and Definitions
subclass of: Cell adhesion protein

Image Statistical analysis
type: Class with Synonyms and Definitions
subclass of: Parameter Extraction Algorithm

Parameter Extraction Algorithm
type: Class with Synonyms and Definitions
comment: e.g. extract MRI cerebral blood volume
subclass of: Image Analysis Technique

KB 788804 Class18
type: Cell line
name: U87 cell line

Connected_Location
type: Class with Synonyms and Definitions
comment: e.g. connected to or adhered to another object
subclass of: Locational Parameter

Adjacency
type: Class with Synonyms and Definitions
subclass of: Locational Parameter

KB 788804 Class19
type: Transduced cell
name: EGFR transduced U87 cells

Architectural Parameter
type: Class with Synonyms and Definitions
comment: e.g. triangular, spiral
subclass of: Anatomical Measurement

Fusion protein
type: Class with Synonyms and Definitions
subclass of: Cell surface Protein

Near-infrared fluorescence (NIRF)
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging

Intravascular ultrasound
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

Deglutition disorder
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Diffusion weighted MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Differential_Interference_Contrast_(DIC)
type: Class with Synonyms and Definitions
subclass of: Light Microscope

Optic nerve disease
type: Class with Synonyms and Definitions
subclass of: Ophthalmologic disease

Vascular Space
type: Class with Synonyms and Definitions
subclass of: Anatomical space

Anatomical space
type: Class with Synonyms and Definitions
subclass of: Anatomical component
comment: Immaterial component of the animal body. Import Anatomical Space class from FMA

Lymphoma
type: Class with Synonyms and Definitions
subclass of: Oncologic disease pathology

Lung
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Scanning optical microscope
type: Class with Synonyms and Definitions
subclass of: Optical Microscope

Individualized treatment
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

Dark-field
type: Class with Synonyms and Definitions
subclass of: Light Microscope

M mode
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

Cryoelectron_Micrscope
type: Class with Synonyms and Definitions
subclass of: Electron Microscope

NSOM
type: Class with Synonyms and Definitions
subclass of: Near-field Probe Microscope

Autoimmune disease
type: Class with Synonyms and Definitions
subclass of: Immunologic disease

Gastrointestinal hemorrhage
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Physiological temperature biomarker
type: Class with Synonyms and Definitions
subclass of: Functional Measurement

B mode
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

Thickness
type: Class with Synonyms and Definitions
subclass of: Size_Parameter

KB 112484 Class1
type: Wild strain
strain name: DBA/2

Pulsed wave
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

Disease Status Update
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

Pig
type: Class with Synonyms and Definitions
subclass of: Non-human mammalian organism

Cone Beam CT
type: Class with Synonyms and Definitions
subclass of: Multi-slice CT (Multi-row detector CT)

Multi-slice CT (Multi-row detector CT)
type: Class with Synonyms and Definitions
subclass of: Computed Tomography

Coisogenic strain
type: Class with Synonyms and Definitions
subclass of: Mouse

Drug Efficacy
type: Class with Synonyms and Definitions
subclass of: Preclinical

Vitamin
type: Class with Synonyms and Definitions
subclass of: Chemically Synthetic Molecule

Quantum dot
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging agent

Roughness
type: Class with Synonyms and Definitions
subclass of: Texture_Parameter

Fludeoxyglucose F 18
type: Class with Synonyms and Definitions
comment: NCI thesaurus
subclass of: Glucose Analog

Glucose Analog
type: Class with Synonyms and Definitions
subclass of: Monosaccharide

Monosaccharide
type: Class with Synonyms and Definitions
subclass of: Small Molecule

Quantum Dot_
type: Class with Synonyms and Definitions
subclass of: Nanoprobe

Scanning_Tunneling_Microscope
type: Class with Synonyms and Definitions
subclass of: Scanning Probe Microscope

Scanning Probe Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

Rabbit
type: Class with Synonyms and Definitions
subclass of: Non-human mammalian organism

Right Neck
type: Class with Synonyms and Definitions
subclass of: Neck

T2* weighted MRI
type: Class with Synonyms and Definitions
subclass of: T2-weighted MRI

T2-weighted MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

TOF PET
type: Class with Synonyms and Definitions
subclass of: Positron Emission Tomography

Linear registration algorithm
type: Class with Synonyms and Definitions
subclass of: Image registration algorithm

Transgenic engineering
type: Class with Synonyms and Definitions
subclass of: Genetic engineering

Integrin
type: Class with Synonyms and Definitions
subclass of: Cell adhesion protein

Thymus
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Hypertension
type: Class with Synonyms and Definitions
subclass of: Vascular disease

Power doppler
type: Class with Synonyms and Definitions
subclass of: Doppler

Doppler
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

Cytoskeletal protein
type: Class with Synonyms and Definitions
subclass of: Protein__

Binding Affinity Biomarker
type: Class with Synonyms and Definitions
subclass of: Functional Measurement

Hippocampus
type: Class with Synonyms and Definitions
subclass of: Brain

Nuclear receptor
type: Class with Synonyms and Definitions
subclass of: Intracellular receptor

Intracellular receptor
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Amino Acid
type: Class with Synonyms and Definitions
subclass of: Small Molecule

Beagle
type: Class with Synonyms and Definitions
subclass of: Dog

Dog
type: Class with Synonyms and Definitions
subclass of: Non-human mammalian organism

Gold Nanoparticle
type: Class with Synonyms and Definitions
subclass of: Nanoprobe

Abdominal pain
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Polymers
type: Class with Synonyms and Definitions
subclass of: Microbubble shell

Syndrome
type: Class with Synonyms and Definitions
subclass of: Disease

Perimeter
type: Class with Synonyms and Definitions
subclass of: Size_Parameter

Green fluorescent protein
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Fluorescence protein tomography (FPT)
type: Class with Synonyms and Definitions
subclass of: Fluorescence mediated tomography (FMT)

Fluorescence mediated tomography (FMT)
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging

Helical CT
type: Class with Synonyms and Definitions
subclass of: Computed Tomography

Metabolic rate biomarker
type: Class with Synonyms and Definitions
subclass of: Functional Measurement

KB 129148 Class8
type: Transgenic model
genetic background: C57BL/6
strain name: C57BL/6-Tg(CD2-Tgfbr2)Grs
name: C57BL/6 DNTGFRII
gene knockin or knockout: Gene Knockin
mutant gene: Tgfbr2 (transforming growth factor, beta receptor II)

KB 701549 Class1
type: Imaging Subject
name: Zebra

PET/CT
type: Class with Synonyms and Definitions
subclass of: Multi-modality

Multi-modality
type: Class with Synonyms and Definitions
subclass of: Acquisition Device

Parasitic infectious disease
type: Class with Synonyms and Definitions
subclass of: Infectious disease pathology

Uterus
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Somatostatin receptor
type: Class with Synonyms and Definitions
subclass of: Membrane receptor

Phase Contrast
type: Class with Synonyms and Definitions
subclass of: Light Microscope

Cholestasis
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Cat
type: Class with Synonyms and Definitions
subclass of: Non-human mammalian organism

Biodistribution
type: Class with Synonyms and Definitions
subclass of: Preclinical

NSCLC
type: Class with Synonyms and Definitions
subclass of: Carcinoma

Continous wave
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

Aneurysm
type: Class with Synonyms and Definitions
subclass of: Vascular disease

Cardiac Gated CT
type: Class with Synonyms and Definitions
subclass of: Computed Tomography

KB 579095 Class7
type: Adenocarcinoma
name: Prostate Cancer

Paleness
type: Class with Synonyms and Definitions
subclass of: Dermatologic disease

Thrombosis
type: Class with Synonyms and Definitions
subclass of: Multicellular process

Dual energy
type: Class with Synonyms and Definitions
subclass of: Computed Tomography

Cardiorespiratory arrest
type: Class with Synonyms and Definitions
subclass of: Cardiovascular disease

Magnetic Resonance Spectroscopy
type: Class with Synonyms and Definitions
subclass of: Magnetic resonance imaging

Ex vivo tissue biopsy
type: Class with Synonyms and Definitions
subclass of: Ex vivo subject

Ex vivo subject
type: Class with Synonyms and Definitions
definition: Living tissue in an artificial environment outside the organism for no more than 24 hours, with minimum alteration of natural conditions
subclass of: Imaging Subject

Tyrosinase
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Endoplasmic reticulum receptor
type: Class with Synonyms and Definitions
subclass of: Intracellular receptor

Liver
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Consomic strain
type: Class with Synonyms and Definitions
subclass of: Mouse

Central Nervous System
type: Class with Synonyms and Definitions
subclass of: Systemic Target

Systemic Target
type: Class with Synonyms and Definitions
subclass of: Biological Target

Caged Fluorescent Dye Label123
type: Class with Synonyms and Definitions
subclass of: Immunofluorescent Label

Superparamagnetic iron oxide particle (SPIO)
type: Class with Synonyms and Definitions
subclass of: Iron nanoparticle

Tetracycline induced gene expression
type: Class with Synonyms and Definitions
subclass of: Induced gene expression

VEGF
type: Class with Synonyms and Definitions
subclass of: Growth factor

Blastoma
type: Class with Synonyms and Definitions
subclass of: Oncologic disease pathology

Nucleotide
type: Class with Synonyms and Definitions
subclass of: Small Molecule

Seizure
type: Class with Synonyms and Definitions
subclass of: Neurologic disease

Cerebrum
type: Class with Synonyms and Definitions
subclass of: Brain

Tetracycline induced gene silencing
type: Class with Synonyms and Definitions
subclass of: Induced gene expression

Diffuse optical tomography
type: Class with Synonyms and Definitions
subclass of: Whole Animal Optical Imaging

liver disease
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

KB 129148 Class3
type: Wild strain
strain name: FVB.129

Tumor cell
type: Class with Synonyms and Definitions
subclass of: Cellular Target

Hair-disease
type: Class with Synonyms and Definitions
subclass of: Dermatologic disease

Nitrogen-13
type: Class with Synonyms and Definitions
subclass of: Radioisotope

Respiratory disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Monoclonal Antibody
type: Class with Synonyms and Definitions
subclass of: Antibody__

KB 129148 Class4
type: Targeted Mutant Mouse
genetic background: FVB.129
mutant gene: Trp53
strain name: FVB.129-Trp53
gene knockin or knockout: Gene Knockout

Scanning_Electron_Microscope
type: Class with Synonyms and Definitions
subclass of: Electron Microscope

Dilation
type: Class with Synonyms and Definitions
subclass of: Deformation Parameter

Near field scanning optical microscope
type: Class with Synonyms and Definitions
subclass of: Scanning confocal microscope

Scanning confocal microscope
type: Class with Synonyms and Definitions
subclass of: Confocal Microscope

Confocal Microscope
type: Class with Synonyms and Definitions
subclass of: Optical Microscope

Dermatitis
type: Class with Synonyms and Definitions
subclass of: Dermatologic disease

Spleen
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Dopamine-2 receptor
type: Class with Synonyms and Definitions
subclass of: Membrane receptor

Blood
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Fission yeast
type: Class with Synonyms and Definitions
subclass of: Yeast

Digital Fluoroscopy
type: Class with Synonyms and Definitions
subclass of: Fluoroscopy

Alzheimer dementia
type: Class with Synonyms and Definitions
subclass of: Neurologic disease

Macrophage
type: Class with Synonyms and Definitions
subclass of: Cellular Target

Kinase Inhibitor therapy
type: Class with Synonyms and Definitions
comment: Biological Intervention is sort of similar to biomarker use/application
subclass of: Anticancer therapy

Atomic_Force_Microscope
type: Class with Synonyms and Definitions
subclass of: Scanning Probe Microscope

Small molecule anitcancer drug
type: Class with Synonyms and Definitions
subclass of: Anticancer therapy

Cancer Model
type: Class with Synonyms and Definitions
subclass of: Model of Disease

Model of Disease
type: Class with Synonyms and Definitions
subclass of: Model
comment: NCI thesaurus

Ligase
type: Class with Synonyms and Definitions
subclass of: Enzyme

Large Superparamagnetic Iron Oxide Nanoparticle
type: Class with Synonyms and Definitions
subclass of: Superparamagnetic Iron Oxide Nanoparticle

Gastrin releasing peptide receptor
type: Class with Synonyms and Definitions
subclass of: Membrane receptor

Photonic_Force_Microscope
type: Class with Synonyms and Definitions
subclass of: Scanning Probe Microscope

Multispectral imaging
type: Class with Synonyms and Definitions
subclass of: Whole Animal Optical Imaging

Albumin
type: Class with Synonyms and Definitions
subclass of: Proteins and Polypeptide

Hepatocyte
type: Class with Synonyms and Definitions
subclass of: Cellular Target

Urinary Bladder
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Pigmentation-disorder
type: Class with Synonyms and Definitions
subclass of: Dermatologic disease

Ultraviolet Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

Prognosis
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

mRNA
type: Class with Synonyms and Definitions
subclass of: RNA

RNA
type: Class with Synonyms and Definitions
subclass of: Molecular Target

Diagnosis
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

Baboon
type: Class with Synonyms and Definitions
subclass of: Non-human mammalian organism

Correlation
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

Screening
type: Class with Synonyms and Definitions
subclass of: Clinical Endpoint

Multi-Photon Microscope
type: Class with Synonyms and Definitions
subclass of: Optical Microscope

Scintigraphy
type: Class with Synonyms and Definitions
subclass of: Radionuclide imaging

Matrix metalloproteinase
type: Class with Synonyms and Definitions
subclass of: Protease

Laminin
type: Class with Synonyms and Definitions
subclass of: Proteoglycan

Proteoglycan
type: Class with Synonyms and Definitions
subclass of: Extracellular matrix Protein

Gamma camera/Anger camera
type: Class with Synonyms and Definitions
subclass of: Autoradiography

Autoradiography
type: Class with Synonyms and Definitions
subclass of: Radionuclide imaging

Isomerase
type: Class with Synonyms and Definitions
subclass of: Enzyme

T cell proliferation
type: Class with Synonyms and Definitions
subclass of: Cell proliferation

Cell proliferation
type: Class with Synonyms and Definitions
subclass of: Cellular process

Parathyroid disease
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

Ex vivo cells
type: Class with Synonyms and Definitions
subclass of: Ex vivo subject

Negative Change
type: Class with Synonyms and Definitions
subclass of: Measurement of Change

Transcription
type: Class with Synonyms and Definitions
subclass of: Subcellular process

Arterial spin labeling MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Concentration biomarker
type: Class with Synonyms and Definitions
subclass of: Kinetic biomarker

Affibody
type: Class with Synonyms and Definitions
subclass of: Antibody Fragment

Fluid attenuation inversion recovery (FLAIR)
type: Class with Synonyms and Definitions
subclass of: Acquisition Device

Fungal infectious disease
type: Class with Synonyms and Definitions
subclass of: Infectious disease pathology

Heart
type: Class with Synonyms and Definitions
subclass of: Multicellular/Organ-level Target

Lymph node
type: Class with Synonyms and Definitions
subclass of: Anatomical structure

Anatomical structure
type: Class with Synonyms and Definitions
subclass of: Anatomical component
comment: Import Anatomical Structure class from FMA

Density
type: Class with Synonyms and Definitions
subclass of: Morphological Parameter

Amount_of_Shared_Space
type: Class with Synonyms and Definitions
subclass of: Locational Parameter

Proximity
type: Class with Synonyms and Definitions
subclass of: Locational Parameter

Metastatsis
type: Class with Synonyms and Definitions
subclass of: Cellular process

Transferase
type: Class with Synonyms and Definitions
subclass of: Enzyme

Luciferase
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Xenograft rat subject
type: Class with Synonyms and Definitions
subclass of: Rat subject

Intestinal obstruction
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Optical frequency domain imaging (OFDI)
type: Class with Synonyms and Definitions
subclass of: Whole Animal Optical Imaging

Adhesion efficiency of US microbubble
type: Class with Synonyms and Definitions
subclass of: Quantitative Imaging Biomarker

Myocardial ischemia
type: Class with Synonyms and Definitions
subclass of: Ischemia

Ischemia
type: Class with Synonyms and Definitions
subclass of: Vascular disease

Inflammation
type: Class with Synonyms and Definitions
subclass of: Multicellular process

Galactose
type: Class with Synonyms and Definitions
subclass of: Microbubble shell

Vomiting
type: Class with Synonyms and Definitions
subclass of: Gastrointestinal disease

Raman imaging
type: Class with Synonyms and Definitions
subclass of: Whole Animal Optical Imaging

Super-resolution fluorescence microscopy
type: Class with Synonyms and Definitions
subclass of: Fluorescence imaging
comment: Is this used for whole animal imaging????

Musculoskeletal disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Arthritis
type: Class with Synonyms and Definitions
subclass of: Rheumatologic disease

Rheumatologic disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Fibronectin
type: Class with Synonyms and Definitions
subclass of: Extracellular matrix glycoprotein

Extracellular matrix glycoprotein
type: Class with Synonyms and Definitions
subclass of: Extracellular matrix Protein

In vitro primary cell
type: Class with Synonyms and Definitions
subclass of: Cell line

Cell line
type: Class with Synonyms and Definitions
subclass of: In vitro cell

In vitro cell
type: Class with Synonyms and Definitions
subclass of: In vitro subject

Striatum
type: Class with Synonyms and Definitions
subclass of: Brain

Oligonucleotide
type: Class with Synonyms and Definitions
subclass of: Nucleic Acid

Nucleic Acid
type: Class with Synonyms and Definitions
subclass of: Biological macromolecule

Phantom experimental subject
type: Class with Synonyms and Definitions
subclass of: Imaging Subject

SPECT/CT
type: Class with Synonyms and Definitions
subclass of: Multi-modality

Gadolinium
type: Class with Synonyms and Definitions
subclass of: Atom

Fibrillin
type: Class with Synonyms and Definitions
subclass of: Extracellular matrix glycoprotein

Fluorescence Resonance Energy Transfer (FRET)
type: Class with Synonyms and Definitions
subclass of: Laser_based_Optical_Microscope

Enlargement
type: Class with Synonyms and Definitions
subclass of: Deformation Parameter

Arginine kinase
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Adrenal insufficiency
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

Headache disorder
type: Class with Synonyms and Definitions
subclass of: Neurologic disease

PET/MRI
type: Class with Synonyms and Definitions
subclass of: Multi-modality

DNA__
type: Class with Synonyms and Definitions
subclass of: Nucleic Acid

Sex differentiation disorder
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

Low density lipoprotein
type: Class with Synonyms and Definitions
subclass of: Molecular Target
comment: oxidized

Pathogen
type: Class with Synonyms and Definitions
comment: external?
subclass of: Organismal Target

Organismal Target
type: Class with Synonyms and Definitions
subclass of: Biological Target

High field MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Hematologic disease
type: Class with Synonyms and Definitions
subclass of: Systemic disease pathology

Bacterial infectious disease
type: Class with Synonyms and Definitions
subclass of: Infectious disease pathology

Dextran
type: Class with Synonyms and Definitions
subclass of: Polysaccharide

Color doppler
type: Class with Synonyms and Definitions
subclass of: Doppler

Proton density weighted MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Diffusion biomarker
type: Class with Synonyms and Definitions
subclass of: Kinetic biomarker

Barium
type: Class with Synonyms and Definitions
subclass of: X-ray attenuator

Protein kinase
type: Class with Synonyms and Definitions
subclass of: Enzyme

Cardiomyopathy
type: Class with Synonyms and Definitions
subclass of: Cardiovascular disease

Frog
type: Class with Synonyms and Definitions
subclass of: Non-mammalian organism

Oxygen-15
type: Class with Synonyms and Definitions
subclass of: Radioisotope

In vitro tissue biopsy
type: Class with Synonyms and Definitions
subclass of: In vitro subject

Angiogenesis
type: Class with Synonyms and Definitions
subclass of: Multicellular process

Side Effect
type: Class with Synonyms and Definitions
subclass of: Preclinical
synonym: Toxicity

Area
type: Class with Synonyms and Definitions
subclass of: Size_Parameter

beta-Galactosidase
type: Class with Synonyms and Definitions
subclass of: Intracellular protein

Adrenocortical hyperfunction
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

Non-proteoglycan polysaccharide
type: Class with Synonyms and Definitions
subclass of: Extracellular matrix Protein

Proteolysis
type: Class with Synonyms and Definitions
subclass of: Multicellular process

Gonadal disorder
type: Class with Synonyms and Definitions
subclass of: Endocrine disease

Ex vivo bodily substance
type: Class with Synonyms and Definitions
comment: Import Portion of Body Substance class from FMA
subclass of: Ex vivo subject

Infrared Microscope
type: Class with Synonyms and Definitions
subclass of: Microscope

Ophthalmoplegia
type: Class with Synonyms and Definitions
subclass of: Ophthalmologic disease

Hyperpolarized
type: Class with Synonyms and Definitions
subclass of: Magnetic resonance susceptibility

Harmonic imaging
type: Class with Synonyms and Definitions
subclass of: Ultrasound imaging

DCE-MRI
type: Class with Synonyms and Definitions
subclass of: Magnetic Resonance Imaging

Rhesus Monkey
type: Class with Synonyms and Definitions
subclass of: Monkey

Monkey
type: Class with Synonyms and Definitions
subclass of: Non-human mammalian organism

Wild strain
type: Class with Synonyms and Definitions
subclass of: Mouse

Targeted Mutant Mouse
type: Class with Synonyms and Definitions
definition: homologous recombination
subclass of: Genetically engineered mutant mouse

Transgenic model
type: Class with Synonyms and Definitions
comment: although transgenic might be targeted as well, but both NCI mouse model database and Jackson lab have two categories: targeted mutant and transgenic mouse
subclass of: Targeted Mutant Mouse
definition: mouse altered by gene transfer

Transduced cell
type: Class with Synonyms and Definitions
subclass of: In vitro cell